Results 91 to 100 of about 2,131,700 (307)

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Development and Validation of a Risk Prediction Model for Interdialytic Hyperkalemia in Patients Undergoing Maintenance Hemodialysis

open access: yesRisk Management and Healthcare Policy
Pan Wang,1,* Jun-Nan Xiao,1,* Yan-Yu Liu,2 Long Xiao,1 Jie-Li Chen,1 Yu Wang,1 Li-Hua Yang,3 Xiu-Li Feng4 1Blood Purification Centre, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, 510000, People’s Republic of ...
Wang P   +7 more
doaj  

Density matrix purification due to continuous quantum measurement

open access: yes, 1999
We consider the continuous quantum measurement of a two-level system, for example, a single-Cooper-pair box measured by a single-electron transistor or a double-quantum dot measured by a quantum point contact.
Alexander N Korotkov   +5 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The Neutrophil Percentage-to-Albumin Ratio as a New Predictor of All-Cause Mortality in Maintenance Hemodialysis Patients

open access: yesInternational Journal of General Medicine
Changjing Shi,1,* Juan Wang,2,* Weichen Liu,2 Yiyi Mo,2 Yuan Huang,2 Xiaoxiao Wei,2 Dongmei Huo,2,* Aifang Huang2,* 1Information Technology Center, The First Affiliated Hospital of Guangxi Medical University, Nanning ...
Shi C   +7 more
doaj  

PURIFICATION OF THROMBIN [PDF]

open access: yesJournal of General Physiology, 1942
1. Under certain conditions crude prothrombin changes to thrombin without the addition of extraneous activators and in the absence of ionic calcium. 2. Thrombin is soluble in 0.45 saturated ammonium sulfate, whereas crude prothrombin is not. 3.
openaire   +2 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

The effect of the erythropoietin resistance index on brain hemorrhage and infarction risk in maintenance hemodialysis patients: a retrospective cohort study [PDF]

open access: yesPeerJ
Background Maintenance hemodialysis (MHD) is the main renal replacement therapy for patients with end-stage renal disease, and erythropoietin (EPO) is the main therapy for renal anemia in patients receiving maintenance hemodialysis. However, the risks of
Mingyu Liu   +6 more
doaj   +2 more sources

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