Results 91 to 100 of about 148,463 (294)
The Purine Salvage Pathway and the Restoration of Cerebral ATP: Implications for Brain Slice Physiology and Brain Injury [PDF]
, 2017 Bruno G. Frenguelli
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Food Bioengineering, EarlyView.Screening and modification of probiotics that can efficiently reduce uric acid provide a new strategy for food‐grade hyperuricemia intervention. ABSTRACT Hyperuricemia has become one of the most prevalent global epidemics, significantly impacting both the economy and the health of individuals.
Le Wang +7 more
wiley +1 more source
New Strategy That Delays Progression of Amyotrophic Lateral Sclerosis in G1H-G93A Transgenic Mice: Oral Administration of Xanthine Oxidoreductase Inhibitors That Are Not Substrates for the Purine Salvage Pathway [PDF]
, 2016 Shinsuke Kato +3 more
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Food Frontiers, EarlyView.Auricularia auricula polysaccharides (AAP; 100, 200, and 400 mg/kg) protect against acute lung injury (ALI) by dose‐dependently remodeling the gut microbiota and modulating associated metabolic pathways via the gut‐lung axis, thereby enhancing pulmonary anti‐inflammatory and antioxidant capacity to ultimately prevent tissue damage.
Haili Niu +8 more
wiley +1 more source
POPULATION DYNAMICS OF PURINE AND PYRIMIDINE ANALOG SENSITIVE AND RESISTANT MAMMALIAN CELLS GROWN IN CULTURE1 2 [PDF]
, 1972 John Morrow
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Food Frontiers, EarlyView.This large cohort study of 45,664 participants from the UK Biobank provides strong epidemiological evidence that fish oil use was associated with 12% and 7% lower risks of obesity and high body fat percentage, respectively. Mechanistically, marine n‐3 polyunsaturated fatty acids mitigate obesity traits through PRDM16‐driven gene–nutrient interactions ...
Xiaohui Liu +12 more
wiley +1 more source
Heterocyclic Nitrogen Compounds as Potential PDE4B Inhibitors in Activated Macrophages
Applied SciencesCyclic-nucleotide phosphodiesterases (PDEs) represent a superfamily of enzymes playing a pivotal role in cell signaling by controlling cAMP and cGMP levels in response to receptor activation.
Simona Todisco +8 more
doaj +1 more source
iNew Medicine, EarlyView.Metabolomic & lipidomic analysis reveals metabolic overlap between CAD & T2DM, highlighting 7 key metabolites as potential biomarkers. A predictive model based on these achieves high accuracy, potentially advancing precision medicine & metabolic insights.
Zhihua Wang +9 more
wiley +1 more source
Journal of Clinical Laboratory Analysis, EarlyView.We evaluated a colorimetric assay using clinical reagents for determining Ca, IP, and Zn in human milk. Significant correlations were observed between Ca, IP, and Zn levels determined by colorimetric assay and Ca, total P, and Zn levels determined by ICP‐AES.
Miori Tanaka +3 more
wiley +1 more source