Results 111 to 120 of about 157,697 (307)
MoleculesChagas disease and leishmaniasis are two neglected tropical diseases that affect millions of people in low- and middle-income tropical countries. These diseases caused by protozoan parasites pose significant global health challenges, which have been ...
Emmanuel Awucha Nwoke +4 more
doaj +1 more source
Adaptive Genomic Divergence Across Altitudes in Capsella bursa‐pastoris
Biological Diversity, EarlyView.Genomic divergence was observed between high‐altitude and low‐altitude populations of Capsella bursa‐pastoris in China, consistent with an important role of ecological factors. Candidate adaptive loci associated with enhanced energy metabolism, photoprotection, and growth plasticity under altitudinal stress were identified.
Lu Liu +4 more
wiley +1 more source
Food Science and Human WellnessGlobally, hyperuricemia is a growing health, social, and economic problem which could cause gout, chronic kidney diseases and other diseases. There are increasing evidences that a sensible diet makes sense to reduce the risk of hyperuricemia. This review
Kaina Qiao +5 more
doaj +1 more source
Novel 2,6-bis-(1,2,3-triazol-1-yl)purine, N6-substituted-2-(1,2,3-triazol-1-yl)adenine and 6-alkyl/arylthio-2-(1,2,3-triazol-1-yl)purine and 2-alkylthio-6-(1,2,3-triazol-1-yl)purine nucleosides were synthesized.
Bizdēna, Ērika +2 more
core
RNA‐centric world of retroviruses: unravelling the molecular strategies of genomic RNA packaging
Biological Reviews, EarlyView.ABSTRACT Retroviruses constitute a unique group of RNA viruses that have profoundly influenced both evolutionary trajectories and biomedical research. Their ability to reverse transcribe and integrate into host genomes has shaped genomic architecture across species and contributed to our understanding of oncogenes, gene regulation, and RNA biology ...
Mohammad Abdullah Jehad +5 more
wiley +1 more source
Chemistry – A European Journal, EarlyView.5‐Substituted 2‐(naphthalen‐2‐yl)‐4H‐chromen‐4‐ones are reported as a novel class of highly potent and selective triplex DNA ligands. These ligands induce triplex formation at submicromolar concentrations and inhibit enzymatic activity via ligand‐mediated triplex formation.
Nghia Tran +4 more
wiley +1 more source
New Approach to the Synthesis of Triazolyl Purine Nucleosides
A straightforward way to synthesis of 2,6-bis-(1,2,3-triazol-1-yl)-purine nucleosides has been developed from 2,6-diazidopurine nucleosides and various terminal alkynes.
Bārzdaine, Madara +4 more
core
Chemistry – A European Journal, EarlyView.The introduction outlines the review scope. Microbial cell factories as living drugs cover host–gut microbiota, bacteria, yeast, and other microbial systems, with comparative host advantages. Engineering strategies include synthetic circuits, quorum sensing, and memory.
Cemile Elif Özçelik +3 more
wiley +1 more source
2,6-Bistriazolyl Purine Deoxynucleosides and Their Reactions with Amines
The chemistry of triazolyl-substituted purine nucleosides is attractive since some of them exhibit fluorescent, antiviral and anticancer characteristics. In 2013 our group reported the synthesis of 2,6-bistriazolyl purine nucleosides in ribo- and arabino-
Cīrule, Dace +3 more
core
Chemistry – A European Journal, EarlyView.Monosubstituted N‐arylhydroxylamines represent a unique subclass of hydroxylamines that act as pivotal intermediates in redox transformations and as versatile platforms for further synthetic transformations. They serve as key building blocks in the synthesis of architecturally complex heterocycles and other valuable organic compounds.
Michael G. Kallitsakis +2 more
wiley +1 more source