Results 161 to 170 of about 157,697 (307)

Die Purine der Lunge

open access: yes, 1909
DIE PURINE DER LUNGE Details: Zeitschrift für physiologische Chemie: 1.1877-20.1895 Hoppe-Seyler's Zeitschrift für physiologische Chemie: 21.1895- 112.1921 (-) Hoppe-Seyler's Zeitschrift für Physiologische Chemie (62) (a0001) Die ...
Sieber, N. W. Dzierzgowski
core  

Small‐Molecule Kinase Inhibitors Modulating Circadian Rhythms

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT The circadian clock mechanism generates 24‐h rhythms crucial for regulating various physiological processes, and its dysregulation has been implicated in numerous diseases. In cells, the circadian clock operates through a transcriptional‐translational feedback loop, where phosphorylation plays a pivotal role in maintaining accurate circadian ...
Irene Castellino   +3 more
wiley   +1 more source

Repurposing Purine Analog Antivirals to Modulate Serum Uric Acid: Evidence From Real-World Data. [PDF]

open access: yesClin Transl Sci
Magagnoli J   +5 more
europepmc   +1 more source

A Synthetic Route to 2,6-Bis-triazolyl Purine Deoxynucleosides via Click Chemistry

open access: yes
3',5'-O-Protected 2,6-diazidopurine deoxynucleosides have been obtained in multistep synthesis either from deoxyguanosine or by direct glycosylation of diazidopurine sodium salt.
Cīrule, Dace   +4 more
core  

Longitudinal Single‐Cell Transcriptomic Profiling Reveals Dynamic Immune Cell Alterations During Burosumab Therapy in X‐Linked Hypophosphatemia

open access: yesPediatric Discovery, EarlyView.
This longitudinal single‐cell study reveals dynamic immune remodeling during burosumab therapy in pediatric X‐linked hypophosphatemia (XLH), highlighting coordinated changes in T cell subtypes (Th2, Th17, and Treg) and natural killer cell subtypes (NK2 and NK3) and immune pathways linked to osteoclast differentiation and treatment response.
Yue Xie   +6 more
wiley   +1 more source

The enzymatic and chemical synthesis of nucleoside analogues using N-deoxyribosyltransferase from Lactobacillus leichmannii [PDF]

open access: yes
N-deoxyribosyltransferase catalyses the transfer of 2-deoxy-I 2.3, -dideoxyand 2,5-dideoxyribose sugars between purine and pyrimidine bases. In this work, a crude extract of N-deoxyribosyltransferase from Lactobacillus leichmannii was used in the ...
Hicks, Nicola
core  

SPROUTS_DB: An Implemented Database of Contaminants for Extracellular Vesicle Proteomics Studies

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Current proteomics techniques allow rapid identification and quantification of proteins within any given biological source. However, LC–MS/MS proteomics is vulnerable to laboratory and sample‐associated contaminants. Therefore, accurate identification and annotation of such contaminants is crucial for development of reliable databases ...
Maria Gaetana Giovanna Pittalà   +10 more
wiley   +1 more source

purine

open access: yes
Citation: 'purine' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.09717 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

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