Results 161 to 170 of about 134,014 (261)

Nanoelectronic Detection of Opioids: Machine Learning‐Powered Screening With Carbon Nanotube Field‐Effect Transistor Sensor Array

Small, EarlyView.
A carbon nanotube field‐effect transistor (NTFET) sensor array is constructed to screen different opioids with machine learning models. Codeine, fentanyl, hydrocodone, and morphine are tested using the NTFET sensor array and classified with both conventional supervised learning models and deep learning models.
Zhengru Liu, Mehdy Dousty, Wenting Shao, Jieyu Wang, Samia Afrin, Wuqi Li, Ervin Sejdić, Alexander Star   +7 more
wiley   +1 more source

USP5 regulates purine metabolism and represents a therapeutic target in esophageal cancer. [PDF]

Cell Death Dis
Zhao K, Zhang L, Yan M, Fang S, Wang Z, Song Y, Liu M, Zhang C, Shao Y, Jia X, Guo Q, Guo M, Yin J, Jin G, Dong Z.   +14 more
europepmc   +1 more source

Active pH Modulation by Proton Channel‐Peptide Nucleic Acid Complex for Effective siRNA Endosomal Escape

Small, EarlyView.
A bioinspired siRNA nanocarrier is engineered by integrating an influenza A M2 proton channel with siRNA through a peptide nucleic acid linker on liposome surfaces. Active proton transport amplifies osmotic stress within endosomes, triggering membrane rupture and cytosolic release.
Seongmin Ga, Nam Hyeong Kim, Si Yeon Ryu, Kyeonghyun Kim, Eun Sung Kang, Hayeon Bae, Seungmin Ryu, Suhyeon Kim, Yeontae Jang, Bok‐Soo Lee, Jiyoung Nam, Minah Suh, Jaecheol Lee, Seung‐gu Kang, Jaekyung Hyun, Huong T. Kratochvil, Yong Ho Kim   +16 more
wiley   +1 more source

Screening of purine nucleoside analogues against intracellular Toxoplasma gondii. [PDF]

Int J Parasitol Drugs Drug Resist
Elati HAA, Van Calenbergh S, Sheiner L, de Koning HP.   +3 more
europepmc   +1 more source

Filtration‐Based SERS With In Situ Gold Growth in Bacterial Microenvironment for Rapid Detection of Low‐Level Bacteria

Small Methods, EarlyView.
A filtration‐assisted SERS platform integrating in situ gold growth within the bacterial microenvironment enables rapid and highly sensitive detection of low‐level bacteria in complex biological matrices. By overcoming hotspot–bacteria mismatch, the platform simultaneously achieves selective bacterial identification and rapid antimicrobial ...
Eun‐Bi Jang, Ji Young Lee, Hoeil Chung, Min‐Young Lee   +3 more
wiley   +1 more source

Microcephaly-associated protein WDR62 supports purine metabolism by interacting with co-chaperone BAG2. [PDF]

EMBO J
Morris MJ, Yeap YY, Edwards JR, Chen C, Paolino A, Furness SGB, Millard SS, Pagan JK, Fenlon LR, Ng DCH.   +9 more
europepmc   +1 more source

Dimethyl‐, Diethyl‐, and Propylene Carbonates: An Emerging Class of Green Solvents for Organic Synthesis

The Chemical Record, EarlyView.
This review highlights recent advances in the use of organic carbonates, dimethyl carbonate (DMC), diethyl carbonate (DEC), and propylene carbonate (PC), as solvents in organic synthesis. Based on over seventy studies from the past 6 years, it shows their application in different organic reaction types, emphasizing their role in safer and more ...
Gabriela T. Quadros, Livia C. L. Valente, Thiago Barcellos, Daniela Hartwig, Laura Abenante, Eder J. Lenardão   +5 more
wiley   +1 more source

Chemical Modification of 2,6,9-Trisubstituted Purine CDK Inhibitors: <i>tert</i>-Butylation at <i>N</i>7/<i>N</i>9 and Access to 2,6,7-Trisubstituted Analogs. [PDF]

ACS Omega
Valenta M, Stýskala J.
europepmc   +1 more source

RESEARCHES ON PURINES

Journal of Biological Chemistry, 1911
openaire   +1 more source

Analysis of purine in purine-rich cauliflower

Analysis of purine in purine-rich cauliflower
Purine is a general term for purine nucleotides, nucleosides, bases, and nucleic acid. The amount of purine nucleotides, nucleosides, and bases in purine-rich cauliflower was determined with the use of LC-MS and HPLC, and the ratio of these molecules were compared with in raw and in heated condition.
openaire