Results 141 to 150 of about 245,344 (350)

Purine Phosphoribosyltransferases [PDF]

Journal of Biological Chemistry, 2000
S P, Craig, A E, Eakin
openaire   +2 more sources

Design, synthesis and antiviral evaluation of purine-β-lactam and purine-aminopropanol hybrids

, 2012
Purine-beta-lactam chimera were prepared as a novel class of hybrid systems through N-alkylation of 6-benzylamino- or 6-benzyloxypurine with (omega-haloalkyl)-beta-lactams, followed by reductive ring opening of the beta-lactam ring by LiEt3BH to provide ...
De Vreese, Rob, De Kimpe, Norbert, Dams, Géry, Mollet, Karen, D'hooghe, Matthias, Jonckers, Tim   +5 more
core   +1 more source

2,6-Diazidopurine Nucleosides as Useful Intermediates for the Synthesis of Novel Triazolyl Purine Analogs

Purine nucleosides, 2,6-diazidopurine nucleosides, 2,6-bis-triazolyl purine derivatives, 1,3-dipolar cycloaddition, nucleophilic aromatic ...
Bizdēna, Ērika, Novosjolova, Irina, Turks, Māris   +2 more
core  

Design, Synthesis, and Antiviral Evaluation of Purine-β-lactam and Purine-aminopropanol Hybrids

, 2016
Purine-β-lactam chimera were prepared as a novel class of hybrid systems through N-alkylation of 6-benzylamino- or 6-benzyloxypurine with (ω-haloalkyl)-β-lactams, followed by reductive ring opening of the β-lactam ring by LiEt3BH to provide an entry into
Géry Dams (2074063), Matthias D’hooghe (1789012), Karen Mollet (2074060), Rob De Vreese (2074057), Tim H. M. Jonckers (2074066), Norbert De Kimpe (42373)   +5 more
core   +1 more source

2,6-Bis-Triazolyl Purine Deoxyribo-Nucleosides and Their Reactions with N-Nucleophiles

New 2,6-bis-triazolyl derivatives of purine deoxyribo-nucleosides have been synthesized and their reactions with piperidine and pyrrolidine have been ...
Cīrule, Dace, Bizdēna, Ērika, Novosjolova, Irina, Ozols, Kristers   +3 more
core  

Purine metabolism scheme.

, 2014
ADA, adenosine deaminase; AICAR, 5-aminoimidazole-4-carboxamide ribonucleotide; AMP, adenosine monophosphate; GMP, guanosine monophosphate; GSK, inosine kinase; IMP, inosine monophosphate; IMPDH, inosine 5′-monophosphate dehydrogenase; PNase, purine 5 ...
Vladimir Tolstikov (133808), Sucai Dong (671473), Alexander Nikolayev (671472), Genshi Zhao (671474), Ming-Shang Kuo (671475)   +4 more
core   +1 more source

New Approach to the Synthesis of Triazolyl Purine Nucleosides

A straightforward way to synthesis of 2,6-bis-(1,2,3-triazol-1-yl)-purine nucleosides has been developed from 2,6-diazidopurine nucleosides and various terminal alkynes.
Bārzdaine, Madara, Beļakovs, Sergejs, Bizdēna, Ērika, Novosjolova, Irina, Turks, Māris   +4 more
core  

[1,2,4]Triazolo[1,5-c]pyrimidine Nucleus as Adenosine Receptor Antagonists: Shift in Selectivity from A2A to A3 Adenosine Receptors.

, 2012
[1,2,4]Triazolo[1,5-c]pyrimidine derivatives are reported in literature as A2A adenosine receptor (AR) antagonists useful for the treatment of Parkinson’s disease (PD), senile dementia and depression (1).[1] Several classes of heterocyclic derivatives ...
Ciancetta, Antonella, MORO, STEFANO, SPALLUTO, GIAMPIERO, Paoletta, Silvia, Klotz, Karl Norbert, FEDERICO, STEPHANIE, Cacciari, Barbara   +6 more
core  

Effect of purine starvation on intracellular proline levels.

, 2014
The free intracellular L-proline concentration was determined for purine-replete and purine-starved cells. Bars indicate the fold change between purine-starved versus purine-replete parasites at 24 h (open bar) and 48 h (black bar) post purine removal ...
Joshua F. Alfaro (528143), Kristin E. Burnum-Johnson (503747), Feng Yang (132135), David G. Camp II (218098), Jessica L. Martin (528140), Nicola S. Carter (528144), Phillip A. Yates (528141), Karl K. Weitz (243011), Radika Soysa (528142), Phillip A. Wilmarth (231403), Vladislav A. Petyuk (218084), Peter J. Myler (244412), Richard D. Smith (39311), Larry L. David (231405), Gowthaman Ramasamy (19191)   +14 more
core   +1 more source

Effect of Cyclic Heat Exposure on the Growth Performance and Metabolism of Broilers Fed Palm Kernel Meal

Animal Research and One Health, EarlyView.
The aim of our study is to evaluate the interaction between HS and the incorporation of PKM in broiler chicken diets, as well as its effect on growth performance and metabolism. Based on the results obtained, PKM supplementation failed to mitigate the adverse effects of heat stress in broiler chickens. ABSTRACT The aim of this study was to evaluate the
Ahmed Mijiyawa, Elham Ghashghaei, Okasha Hamada, Huimin Wang, Lijing Sun, Yendouhamtchié Nadiedjoa, Dan Wang, Zhengkai Yue, Clarice Maa Maa Temhoul, Maxwell Ansong Okai, Muhammad Faisal Riaz, Felix Kwame Amevor, Wéré Pitala, Hai Lin   +13 more
wiley   +1 more source