Results 211 to 220 of about 187,335 (337)

Ciba Foundation Symposium on The Chemistry and Biology of Purines. [PDF]

, 1958

openalex   +1 more source

Metformin and Dietary Restriction Counteract Aging via Reducing m6A–Dependent Stabilization of Methionine Synthase mRNA in Brachionus asplanchnoidis (Rotifera)

Aging Cell, EarlyView.
Metformin and dietary restriction modulate m6A to extend lifespan of rotifer, highlighting MTR as a central regulator of aging through methionine metabolism. ABSTRACT Metformin, a medication primarily used to treat diabetes, has gained attentions for its potential antiaging properties.
Yu Zhang, Xiaojie Liu, Hairong Lian, Yanchao Chai, Yang Zhou, Dongqi Kan, Jilong Ren, Cui Han, Jiaxin Yang   +8 more
wiley   +1 more source

Impact of lifestyle factors and dietary patterns on serum uric acid levels and disease activity in gout: a systematic review. [PDF]

J Health Popul Nutr
Mustafa M, Alshamrani S, Alghamdi L, Danish H, Alamoudi D, Alshamrani G, Alagha A, Alshaikh A, Alqarni S, Bawazir Y.   +9 more
europepmc   +1 more source

THE ENZYMATIC SYNTHESIS OF PURINE RIBOSIDES

, 1947
Herman Μ. Kalckar
openalex   +1 more source

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

British Journal of Pharmacology, EarlyView.
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen, Tamás Kovács, Péter Ferdinandy, Zoltán V. Varga   +3 more
wiley   +1 more source

Inhibition of Purine Metabolism Promotes the Differentiation of Neuroblastoma Driven by MYCN. [PDF]

Cancer Med
Jiang Y, Xiao H, Yang Y, Chen G, Zhang Y, Wu X, Zhang Q, Huang Q, Gao H, Han Y, Zhang A, Jiang D, Zheng L, Li Y, Gao Y.   +14 more
europepmc   +1 more source

THE DETERMINATION OF THE PURINES

, 1941
George H. Hitchings, Cyrus H. Fiske
openalex   +1 more source

Contributions of synaptic energetic dysfunction by microtubule dynamics and microtubule‐based mitochondrial transport disorder to morphine tolerance

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Morphine is among the most powerful analgesic, but its long‐term use can cause tolerance. Synaptic ATP supply is critical for maintaining synaptic transmission. Microtubule‐based mitochondrial transport ensures synaptic energy supply.
Zheng Li, Jie Liu, Jie Ju, Xiaoling Peng, Wei Zhao, Jihao Ren, Xiaoqian Jia, Jihong Wang, Ye Tu, Feng Gao   +9 more
wiley   +1 more source

Single-Cell and Spatial Transcriptomics Explore Purine Metabolism-Related Prognostic Risk Model and Tumor Immune Microenvironment Modulation in Ovarian Cancer. [PDF]

Hum Mutat
Liu Y, Geng R, Zhao S, Yang J, Liu J, Zheng Y, Tang W.   +6 more
europepmc   +1 more source

Stimulation of the Respiration of Chlorella Vulgaris by Purines and Purine Analogues [PDF]

Plant Physiology, 1960
Michael K. Bach, J. Fellig
openaire   +2 more sources