Roles of nucleotide metabolism in pancreatic cancer. [PDF]
Liu Q +5 more
europepmc +1 more source
Novel nanoparticle‐mediated plasmid delivery in bacteria for difficult applications
Abstract BACKGROUND This study presents the development and application of magnetite/silver‐pDMAEMA‐PEG‐BUFII nanobioconjugates as an advanced plasmid delivery system in bacteria. These nanobioconjugates demonstrated superior efficiency compared to traditional methods in four challenging applications: (i) genomic editing in Gram‐positive bacteria; (ii)
Laura D. Páez‐Angarita +6 more
wiley +1 more source
Pediococcus acidilactici GR-5 alleviates hyperuricemia by degrading purine nucleosides and improving gut microbiota metabolism. [PDF]
Ji J +9 more
europepmc +1 more source
Association of maternal biliary disease with hepatopancreatobiliary morbidity in offspring
Abstract Objectives Maternal biliary disease is common, but the link with offspring hepatopancreatobiliary disease has not been studied. We assessed the association between maternal biliary disease and pediatric hepatopancreatobiliary morbidity. Methods We conducted a retrospective cohort study of 1,271,864 children born between 2006 and 2022 in Quebec,
Nathalie Auger +6 more
wiley +1 more source
The Role of the Intestinal Microbiome in the Pathogenesis and Treatment of Hyperuricemia: A Review. [PDF]
Yang J +6 more
europepmc +1 more source
Synthesis of C2 alkynylated purines, a new family of potent inhibitors of cyclin-dependent kinases
Michel Legraverend +4 more
openalex +1 more source
A member of the gut mycobiota modulates host purine metabolism exacerbating colitis in mice
Tyson R. Chiaro +16 more
semanticscholar +1 more source
Abstract BACKGROUND Over the past two decades, the global incidence of gout has markedly increased, affecting people worldwide. Considering the side effects of xanthine oxidase (XO) inhibitor drugs (e.g. allopurinol and febuxostat) used in the treatment of hyperuricemia and gout, the potential application of phytochemicals has been widely studied.
Tímea Bencsik +6 more
wiley +1 more source
Purine-based chemical probe with HOMO switching for intracellular detection of mercury ions. [PDF]
Boguševičienė K +11 more
europepmc +1 more source

