Results 241 to 250 of about 148,463 (294)

Roles of nucleotide metabolism in pancreatic cancer. [PDF]

Front Immunol
Liu Q, Liu J, Wang S, Bao N, Zhao X, Wang L.   +5 more
europepmc   +1 more source

Design and Synthesis of Novel Purine Analogues as Potential IL‐1β Inhibitors Targeting Vascular Inflammation

Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.
Initial screening of the synthesized compounds revealed that compounds MK175 and MK169 inhibited LPS‐induced IL‐1β release in human aortic smooth muscle cells. ABSTRACT Proinflammatory cytokine interleukin (IL)‐1β is a key mediator of the inflammatory response in atherosclerosis.
Dimitra T. Pournara, Theano Fotopoulou, Geena Paramel, Madelene Lindkvist, Magnus Grenegård, Karin Fransén, Maria Koufaki   +6 more
wiley   +1 more source

RESEARCHES ON PURINES

Journal of Biological Chemistry, 1911
openaire   +1 more source

Venetoclax‐Based Therapy for Early Relapse in Acute Myeloid Leukemia After Allogeneic Hematopoietic Stem Cell Transplantation: A Case Report and Minireview

Cancer Reports, Volume 9, Issue 1, January 2026.
ABSTRACT Background Refractory/relapsed acute myeloid leukemia (R/R‐AML) typically exhibits resistance to conventional chemotherapy, resulting in a poor overall therapeutic outcome. Salvage allogeneic hematopoietic stem cell transplantation (allo‐HSCT) is the primary treatment option in such patients.
Yufeng Du, Mohammad Arian Hassani, Chunhong Li, Zhijia Zhao, Yikun Liu, Chengtao Zhang, Jinsong Yan   +6 more
wiley   +1 more source

The Role of the Intestinal Microbiome in the Pathogenesis and Treatment of Hyperuricemia: A Review. [PDF]

Food Sci Nutr
Yang J, Chen J, Liu Z, Qu Y, Yue X, Yuan B, Li M.   +6 more
europepmc   +1 more source

Classic Hairy Cell Leukemia With MAP2K1 Mutation: Diagnosis and Targeted Therapy

American Journal of Hematology, Volume 101, Issue 2, Page 339-340, February 2026.
Andrea Duminuco, Alessandra Venanzi, Alessia Santi, Alessandro Mancini, Alessandra Romano, Enrico Tiacci   +5 more
wiley   +1 more source

Purine-based chemical probe with HOMO switching for intracellular detection of mercury ions. [PDF]

Sci Rep
Boguševičienė K, Jovaišaitė J, Jonusauskas G, Kreiza G, Burcevs A, Kapilinskis Z, Novosjolova I, Turks M, Hean LE, Chu HW, Chang HT, Juršėnas S.   +11 more
europepmc   +1 more source

MTAP-Null Tumors: A Comprehensive Review on Synthetic Vulnerabilities and Therapeutic Strategies. [PDF]

Cells
Subramaniam B, Chong WC, Babaei A, Bornhorst M, Zhang C, Packer R, Nazarian J.   +6 more
europepmc   +1 more source

The impact of bacterial purine metabolism on antibiotic efficacy. [PDF]

NPJ Antimicrob Resist
Stevens CE, Deventer AT, Hobbs JK.
europepmc   +1 more source

The research progress of LACC1. [PDF]

Front Immunol
Li F, Cui X, Yang Q, Nie Y, Wang J, Sun S.   +5 more
europepmc   +1 more source