Results 241 to 250 of about 209,598 (340)

Zebrafish as a model for Catel–Manzke syndrome—identification and characterization of the zebrafish TGDS ortholog

The FEBS Journal, EarlyView.
Zebrafish Tgds, when expressed as a recombinant protein, catalyzes the dehydration of UDP‐D‐glucose, the initial step in the formation of 6‐deoxyhexoses. Corresponding Tgds mutations found in Catel–Manzke syndrome patients lead to reduced enzymatic activity and stability.
Maria Rosaria Coppola, Deianira Bellitto, Erfan Asgari, Virginia Bazzurro, Giorgia Casucci, Francesco Piacente, Matteo Bozzo, Davide Ceresa, Costantino Parisi, Cecilia Winata, Simona Candiani, Michela Tonetti   +11 more
wiley   +1 more source

Resilience and Vulnerabilities of Tumor Cells under Purine Shortage Stress. [PDF]

Clin Cancer Res
Yu J, Jin C, Su C, Moon D, Sun MA, Zhang H, Jiang X, Zhang F, Tserentsoodol N, Bowie ML, Pirozzi CJ, George DJ, Wild R, Gao X, Ashley DM, He Y, Huang J.   +16 more
europepmc   +1 more source

Microbial protein production and purine derivatives in cows.

, 2016
José Alípio Faleiro Neto, Elizângela Mírian Moreira, Ricardo Andrade Reis, Ivan Barbosa Machado Sampaio, H.M. Saturnino, T. C. dos Reis, J. Reed   +6 more
openalex   +1 more source

Prodrugs of purine and pyrimidine analogues for the intestinal di/tri-peptide transporter PepT1: affinity for hPepT1 in Caco-2 cells, drug release in aqueous media and in vitro metabolism

, 2003
Anne Engelbrecht Thomsen, Gerda Marie Friedrichsen, Arne Hagsten Sørensen, Rikke Andersen, Carsten Uhd Nielsen, Birger Brodin, Mikael Begtrup, Sven Frøkjær, Bente Steffansen   +8 more
openalex   +1 more source

Plant organelle C‐to‐U RNA editing factors can operate successfully in yeast (Saccharomyces cerevisiae) as an easily amenable eukaryotic system for their functional analysis

The FEBS Journal, EarlyView.
Plant‐type pentatricopeptide repeat proteins capable of C‐to‐U RNA editing perform faithfully when expressed in a new heterologous system, the yeast Saccharomyces cerevisiae. They were tested with constitutive and inducible expression and with a set of different solubility tags. PPR56, PPR65, and PPR78 from P.
Shyam Ramanathan, Annika Hanraths, Jingchan Xie, Mareike Schallenberg‐Rüdinger, Volker Knoop   +4 more
wiley   +1 more source

Research progress on multidimensional intervention strategies for hyperuricemia: Western medicine, Traditional Chinese Medicine, and emerging therapies. [PDF]

Front Endocrinol (Lausanne)
Li X, Chen Z, Zhang Y, Fan C, Chen L, Xu X, Chang J, Qiang W, Jiang H, Liu C.   +9 more
europepmc   +1 more source

CpRu Complexes Containing Water Soluble Phosphane PTA and Natural Purines Adenine, Guanine and Theophylline: Synthesis, Characterization, and Antiproliferative Properties

, 2019
Lazhar Hajji, Cristobal Saraiba‐Bello, Gaspar Segovia‐Torrente, Franco Scalambra, Antonio Romerosa   +4 more
openalex   +2 more sources

Ultrastructural expansion microscopy reveals unexpected levels of glycosome heterogeneity in African trypanosomes

Journal of Microscopy, EarlyView.
Abstract Kinetoplastid parasites include several species. Trypanosoma brucei causes African sleeping sickness in humans and a wasting disease nagana in livestock. Trypanosoma cruzi is the causative agent of Chagas disease and Leishmania species cause leishmaniasis, which can present with visceral, cutaneous, or mucocutaneous symptoms.
Heidi Anderson, Rhonda Reigers Powell, Meredith Teilhet Morris   +2 more
wiley   +1 more source

Breast milk-saliva interactions in shaping early mucosal immunity. [PDF]

Front Immunol
Song SB, Kim JY.
europepmc   +1 more source

When chemistry meets taxonomy: Studying glycolipidic chemomarkers in pelagic Sargassum spp. (Phaeophyceae) using molecular networking

Journal of Phycology, EarlyView.
Abstract To chemically differentiate the three pelagic Sargassum morphotypes co‐occurring in floating rafts and drifting across the Atlantic Ocean before stranding on West African, Caribbean, and Atlantic Mexican coastlines, we conducted an investigation of their metabolomic profiles.
Charlotte Nirma, Valérie Stiger‐Pouvreau, Marceau Levasseur, David Touboul, Solène Connan, Sylvain Petek   +5 more
wiley   +1 more source