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Feedback Control of Purine Biosynthesis by Purine Ribonucleotides [PDF]
Nature, 1959 IN recent years a number of biosynthetic sequences have been shown to be regulated by feedback mechanisms, which have been of two general types, the first involving regulation of the activity of an enzyme by an inhibitory effect of an end-product1,2, the second involving regulation of the rate of synthesis of an enzyme by negative-induction, or ...
James B. Wyngaarden, Doris M. Ashton
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3 Purine, Purine Nucleoside, and Purine Nucleotide Aminohydrolases
1971Publisher Summary This chapter discusses the chemical significance of adenosine aminohydrolase, 5′-adenylic acid aminohydrolase, adenine nucleoside, nucleotide aminohydrolase, guanine aminohydrolase, and guanosine aminohydrolase. The partially purified adenine aminohydrolase from Azotobacter vinelandii catalyzes the anaerobic conversion of adenine ...
C.H. Suelter, C.L. Zielke
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Protonation-deprotonation of purines and purine nucleosides
Journal of Molecular Structure: THEOCHEM, 1989Abstract The protonation of purines and purine nucleosides at N7 and the HC8 acidity of the cations have been explored by semi-empirical and ab initio MO ...
Donald W. Boerth, Pradip K. Bhowmik
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Biochemical Society Transactions, 1981
Abstract The inherited disorders of purine metabolism associated with renal disease are listed in Table 24.1. They are the sole cause of only a small proportion of all renal disease and are therefore best considered as part of the overall problem of purine, especially uric acid metabolism-related renal disease.
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Abstract The inherited disorders of purine metabolism associated with renal disease are listed in Table 24.1. They are the sole cause of only a small proportion of all renal disease and are therefore best considered as part of the overall problem of purine, especially uric acid metabolism-related renal disease.
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Photochemistry and Photobiology, 1988
Abstract— DNA purine modifications by ultraviolet irradiation have not been as extensively studied as those of pyrimidines. However, a number of such reactions have been identified. These include photochemical addition of amino acids, photoalkylation by alcohols, amines and other compounds, photochemical activation of procarcinogens to mutagenic ...
N J, Duker, P E, Gallagher
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Abstract— DNA purine modifications by ultraviolet irradiation have not been as extensively studied as those of pyrimidines. However, a number of such reactions have been identified. These include photochemical addition of amino acids, photoalkylation by alcohols, amines and other compounds, photochemical activation of procarcinogens to mutagenic ...
N J, Duker, P E, Gallagher
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New England Journal of Medicine, 1976
To delineate the normal function of purine nucleoside phosphorylase and to understand the pathogenesis of the immune dysfunction associated with deficiency of this enzyme, we studied purine metabolism in a patient deficient in purine nucleoside phosphorylase, her erythrocytes and cultured fibroblasts.
David W. Martin +3 more
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To delineate the normal function of purine nucleoside phosphorylase and to understand the pathogenesis of the immune dysfunction associated with deficiency of this enzyme, we studied purine metabolism in a patient deficient in purine nucleoside phosphorylase, her erythrocytes and cultured fibroblasts.
David W. Martin +3 more
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New England Journal of Medicine, 1970
"The biochemistry of uric acid and its relation to gout" was recently (1963) reviewed in a series of articles that appeared in the Medical Progress section of the Journal.1 In this series the bioch...
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"The biochemistry of uric acid and its relation to gout" was recently (1963) reviewed in a series of articles that appeared in the Medical Progress section of the Journal.1 In this series the bioch...
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2003
The activation of adenosine A1, A2 andA3 receptors can protect neurones against damage generated by mechanical or hypoxic/ischaemic insults as well as excitotoxins. A1 receptors are probably effective by suppressing transmitter release and producing neuronal hyperpolarisation.
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The activation of adenosine A1, A2 andA3 receptors can protect neurones against damage generated by mechanical or hypoxic/ischaemic insults as well as excitotoxins. A1 receptors are probably effective by suppressing transmitter release and producing neuronal hyperpolarisation.
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ChemInform Abstract: Synthesis of Certain Alkenyl Purines and Purine Analogues.
ChemInform, 1995AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
T. S. Rao, G. R. Revankar
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Journal of Cellular and Comparative Physiology, 1951
GAR transformylase, which is responsible for the incorporation of formate carbon into what becomes position 8 of the purine ring, has been completely separated from 5-amino-4-imidazolecarboxamide ribotide transformylase (3). The latter enzyme is responsible for the incorporation of formate carbon into position 2 of the purine ring.
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GAR transformylase, which is responsible for the incorporation of formate carbon into what becomes position 8 of the purine ring, has been completely separated from 5-amino-4-imidazolecarboxamide ribotide transformylase (3). The latter enzyme is responsible for the incorporation of formate carbon into position 2 of the purine ring.
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