The HWE‐family histidine kinase PhyK regulates the cell envelope structure of the intracellular pathogen Brucella ovis and affects how the host immune system responds to this bacterium. Deletion of phyK alters bacterial survival in the face of detergent stress and reduces immune activation in infected macrophages.
Xingru Chen+6 more
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CO<sub>2</sub> and electrical stunning differentially affect energy metabolism in pigs. [PDF]
Peukert M+3 more
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Dietary supplementation with glutamate improves the flesh quality of gibel carp (<i>Carassius gibelio</i>) by altering muscle texture characteristics and increasing the deposition of flavour substances. [PDF]
Cai W+9 more
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Purine Metabolism and Dystonia: Perspectives of a Long-Promised Relationship. [PDF]
Sorrentino U+4 more
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Nucleotides enriched under heat stress recruit beneficial rhizomicrobes to protect plants from heat and root-rot stresses. [PDF]
Liu H+16 more
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Purinosomes as a therapeutic target in hepatocellular carcinoma: insights and opportunities. [PDF]
Lin Z+5 more
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Comparison of plasma metabolic profiling between children with hypertrophic obstructive cardiomyopathy and healthy controls. [PDF]
Dong S+9 more
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The biosynthesis of the purines [PDF]
Of the many problems which confront the biologist in his understanding of the operations of the cell, the synthesis of biologically important substances is now the most amenable to solution. It has been the domain of the biochemist to probe into the integrated cellular system by dissembling its enzymatic machinery as a means of studying the complex ...
John M. Buchanan, Standish C. Hartman
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New insights into purine metabolism in metabolic diseases: role of xanthine oxidoreductase activity.
American Journal of Physiology. Endocrinology and Metabolism, 2020Xanthine oxidoreductase (XOR) consists of two different forms, xanthine dehydrogenase (XDH) and xanthine oxidase (XO), and is a rate-limiting enzyme of uric acid production from hypoxanthine and xanthine. Uric acid is the end-product of purine metabolism
M. Furuhashi
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