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An HWE‐Family Histidine Kinase Modulates Brucella Cell Envelope Properties and Host Innate Immune Response

open access: yesMolecular Microbiology, EarlyView.
The HWE‐family histidine kinase PhyK regulates the cell envelope structure of the intracellular pathogen Brucella ovis and affects how the host immune system responds to this bacterium. Deletion of phyK alters bacterial survival in the face of detergent stress and reduces immune activation in infected macrophages.
Xingru Chen   +6 more
wiley   +1 more source

Nucleotides enriched under heat stress recruit beneficial rhizomicrobes to protect plants from heat and root-rot stresses. [PDF]

open access: yesMicrobiome
Liu H   +16 more
europepmc   +1 more source

Comparison of plasma metabolic profiling between children with hypertrophic obstructive cardiomyopathy and healthy controls. [PDF]

open access: yesCardiovasc Endocrinol Metab
Dong S   +9 more
europepmc   +1 more source

The biosynthesis of the purines [PDF]

open access: possibleErgebnisse der Physiologie Biologischen Chemie und Experimentellen Pharmakologie, 1959
Of the many problems which confront the biologist in his understanding of the operations of the cell, the synthesis of biologically important substances is now the most amenable to solution. It has been the domain of the biochemist to probe into the integrated cellular system by dissembling its enzymatic machinery as a means of studying the complex ...
John M. Buchanan, Standish C. Hartman
openaire   +2 more sources
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New insights into purine metabolism in metabolic diseases: role of xanthine oxidoreductase activity.

American Journal of Physiology. Endocrinology and Metabolism, 2020
Xanthine oxidoreductase (XOR) consists of two different forms, xanthine dehydrogenase (XDH) and xanthine oxidase (XO), and is a rate-limiting enzyme of uric acid production from hypoxanthine and xanthine. Uric acid is the end-product of purine metabolism
M. Furuhashi
semanticscholar   +1 more source

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