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Correction to "Synthesis of a New Purine Analogue Class with Antifungal Activity and Improved Potency against Fungal IP<sub>3-4</sub>K". [PDF]

open access: yesACS Infect Dis
Desmarini D   +9 more
europepmc   +1 more source
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New insights into purine metabolism in metabolic diseases: role of xanthine oxidoreductase activity.

American Journal of Physiology. Endocrinology and Metabolism, 2020
Xanthine oxidoreductase (XOR) consists of two different forms, xanthine dehydrogenase (XDH) and xanthine oxidase (XO), and is a rate-limiting enzyme of uric acid production from hypoxanthine and xanthine. Uric acid is the end-product of purine metabolism
M. Furuhashi
semanticscholar   +1 more source

On the relevance of hydroxyl radical to purine DNA damage

Free radical research, 2021
Hydroxyl radical (HO•) is the most reactive toward DNA among the reactive oxygen species (ROS) generated in aerobic organisms by cellular metabolisms. HO• is generated also by exogenous sources such as ionizing radiations.
C. Chatgilialoglu   +4 more
semanticscholar   +1 more source

Purine Release, Metabolism, and Signaling in the Inflammatory Response.

Annual Review of Immunology, 2019
ATP, NAD+, and nucleic acids are abundant purines that, in addition to having critical intracellular functions, have evolved extracellular roles as danger signals released in response to cell lysis, apoptosis, degranulation, or membrane pore formation ...
J. Linden, F. Koch-Nolte, G. Dahl
semanticscholar   +1 more source

PURINE PHOTOPRODUCTS*

Photochemistry and Photobiology, 1988
Abstract— DNA purine modifications by ultraviolet irradiation have not been as extensively studied as those of pyrimidines. However, a number of such reactions have been identified. These include photochemical addition of amino acids, photoalkylation by alcohols, amines and other compounds, photochemical activation of procarcinogens to mutagenic ...
N J, Duker, P E, Gallagher
openaire   +2 more sources

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