Results 51 to 60 of about 124,162 (316)
Advanced Materials Interfaces, EarlyView.The formation of stable clusters of gold nanoparticles with oligonucleotides at different solution conditions is explored. DNA base homogeneity and strand directionality influence the binding with gold nanoparticles leading to interesting clustering behavior that can be relevant for SERS applications.
Shaila Thakur +3 more
wiley +1 more source
Extraterrestrial nucleobases in the Murchison meteorite [PDF]
Earth and Planetary Science Letters 270, 130-136. 15 June 2008, 2008 Carbon-rich meteorites, carbonaceous chondrites, contain many biologically relevant organic molecules and delivered prebiotic material to the young Earth. We present compound-specific carbon isotope data indicating that measured purine and pyrimidine compounds are indigenous components of the Murchison meteorite.
arxiv +1 more source
The Influence of Dietary Purines and Pyrimidines on Purine and Pyrimidine Biosynthesis in Man
Transfusion Medicine and Hemotherapy, 1977 Allopurinol-induced orotaciduria is reduced by dietary ribonucleic acid (RNA), RNA hydrolysate and different nucleotides. These findings are compatible with feedback regulation of pyrimidine biosynthesis by dietary nucleotides. Serum uric acid and urinary uric acid excretion on a purine-free isoenergetic diet reach a minimum after about 10 days and ...
W Gröbner, N Zöllner
openaire +2 more sources
Adjusting Cell‐Surface Interactions Through a Covalent Immobilization of Biomolecules
Advanced Materials Interfaces, EarlyView.This review presents an overview of current and emerging immobilization techniques coupled with an in‐depth investigation of the underlying mechanisms governing the activity and stability of covalently immobilized biomolecules. The aim of this study is to serve as a guide for the development of long‐lasting biomedical coatings with versatile biological
Sara Shakibania +2 more
wiley +1 more source
Journal of Biological Chemistry, 1912 "Reprinted from the Journal of biological chemistry, vol. XI, no. 3, 1912." ; "From the Rudolph Spreckels physiological laboratory of the University of California." ; Cover-title. ; Mode of access: Internet.
openaire +1 more source
Advanced Photonics Research, EarlyView.A family of purinylidene based Ir(III) emitters, namely, f‐ct2a–d, are synthesized and utilized as both dopants and sensitizers in the construction of efficient purple to deep‐blue organic light‐emitting diode devices. It is very challenging to achieve highly efficient and low roll‐off purple to deep‐blue organic light‐emitting diodes (OLEDs) due to ...
Jie Yan +8 more
wiley +1 more source
A cytotoxic survey on 2‐amino‐1H‐imidazol based synthetic marine sponge alkaloid analogues
Drug Development Research, Volume 83, Issue 8, Page 1906-1922, December 2022., 2022 Abstract Here, we describe the synthesis and biologic activity evaluation of 20 novel synthetic marine sponge alkaloid analogues with 2‐amino‐1H‐imidazol (2‐AI) core. Cytotoxicity was tested on murine 4T1 breast cancer, A549 human lung cancer, and HL‐60 human myeloid leukemia cells by the resazurin assay.
Nikolett Gémes +10 more
wiley +1 more source
Advanced Synthesis &Catalysis, EarlyView.Abstract The use of stable photosensitizers made on a multigram‐scale from cheap and available starting materials offers an extraordinary opportunity to translate small‐scale proof‐of‐concept photoreactions to widespread applications in non‐specialized laboratories, thereby promoting the implementation of light‐driven syntheses.
Steven Sittel +5 more
wiley +1 more source
Purine-pyrimidine symmetry, determinative degree and DNA [PDF]
arXiv, 2000 Various symmetries connected with purine-pyrimidine content of DNA sequences are studied in terms of the intruduced determinative degree, a new characteristics of nucleotide which is connected with codon usage. A numerological explanation of CG pressure is proposed. A classification of DNA sequences is given.
arxiv
RFWD3 Reprograms Nucleotide Metabolism Through PHGDH to Induce Chemoresistance In Osteosarcoma
Advanced Science, EarlyView.RFWD3 is identified as a key regulator of cisplatin (DDP) sensitivity in osteosarcoma using a genome‐wide CRISPR screen. RFWD3 promotes PHGDH ubiquitination, enhancing NAD+‐mediated nucleotide biosynthesis. Knocking out RFWD3 sensitized osteosarcoma cells to DDP.
Wenchao Zhang +6 more
wiley +1 more source