A Generalization of the Auslander-Reiten Conjecture for the Bounded Derived Category [PDF]
Archiv der Mathematik: Volume 98, Issue 6 (2012), Page 507-511, 2011 We study the bounded derived category $\D^b(\Rmod)$ of a left Noetherian ring $R$. We give a version of the Generalized Auslander-Reiten Conjecture for $\D^b(\Rmod)$ that is equivalent to the classical statement for the module category and is preserved under derived equivalence.
arxiv +1 more source
Basis for the control of purine biosynthesis by purine ribonucleotides. [PDF]
Journal of Clinical Investigation, 1981 An animal model was used to determine the basis for the increase in purine biosynthesis that results from hepatic depletion of purine nucleotides, such as seen in patients with type I glycogen storage disease or following fructose administration. Mice were injected intravenously with glucose or fructose, 2.5 mg/g of body weight, and the animals were ...
Edward W. Holmes +3 more
openaire +3 more sources
Metabolic engineering of the purine biosynthetic pathway in Corynebacterium glutamicum results in increased intracellular pool sizes of IMP and hypoxanthine [PDF]
, 2012 Background: Purine nucleotides exhibit various functions in cellular metabolism. Besides serving as building blocks for nucleic acid synthesis, they participate in signaling pathways and energy metabolism.
Barduhn, Tobias +5 more
core +1 more source
Evolutionary Trends in RNA Base Selectivity Within the RNase A Superfamily
Frontiers in Pharmacology, 2019 There is a growing interest in the pharmaceutical industry to design novel tailored drugs for RNA targeting. The vertebrate-specific RNase A superfamily is nowadays one of the best characterized family of enzymes and comprises proteins involved in host ...
Guillem Prats-Ejarque +4 more
doaj +1 more source
The dynamics of single spike-evoked adenosine release in the cerebellum [PDF]
, 2010 The purine adenosine is a potent neuromodulator in the brain, with roles in a number of diverse physiological and pathological processes. Modulators such as adenosine are difficult to study as once released they have a diffuse action (which can affect ...
Beierlein +41 more
core +2 more sources
Synthesis a Number of Triazene Compounds Derived From Purine and Studying their Biological Activity on Pathogenic Bacteria [PDF]
مجلة جامعة الانبار للعلوم الصرفة, 2012 In this research a number of compounds were prepared by coupling dizonium salts with purine bases. The structures of the prepared compounds were identified by ultra violet ,infra red spectra and Elemental (C.H.N) analysis .The biological activity of ...
Ahmed .M. Mohamed +2 more
doaj +1 more source
Hoogsteen base pairs proximal and distal to echinomycin binding sites on DNA [PDF]
, 1987 Forms of the DNA double helix containing non-Watson-Crick base-pairing have been discovered recently based on x-ray diffraction analysis of quinoxaline antibiotic-oligonucleotide complexes.
Dervan, Peter B., Mendel, David
core +2 more sources
Synthesis of purines and adenines containing the hexafluoroisopropyl group
Beilstein Journal of Organic Chemistry, 2020 Several new derivatives of adenine, purine, and theophylline containing the (CF3)2CH group connected to a nitrogen atom of the imidazole ring were prepared by the reaction of 2,2,4,4-tetrakis(trifluoromethyl)-1,3-dithietane (1) with the corresponding ...
Viacheslav Petrov +5 more
doaj +1 more source
Metabolites, 2020 Folate deficiency in the critical developmental period has been repeatedly associated with an increased risk of Autism spectrum disorders (ASD), but the key pathophysiological mechanism has not yet been identified. In this work, we focused on identifying
Jan Geryk +5 more
doaj +1 more source
Nucleotides: Structure and Properties [PDF]
, 2005 Nucleotides consist of a nitrogen-containing base, a five-carbon sugar, and one or more phosphate groups. Cells contain many types of nucleotides, which play a central role in a wide variety of cellular processes, including metabolic regulation and the ...
Bowater, RP
core +1 more source