Results 61 to 70 of about 151,646 (288)

Regulating uric acid

eLife
Certain strains of a bacterium found in the gut of some animals, Lactobacillus plantarum, are able to counter hyperuricemia, a condition caused by high levels of uric acid in the blood.
Caihong Hu
doaj   +1 more source

Elevated Serum Purine Levels in Schizophrenia: A Reverse Translational Study to Identify Novel Inflammatory Biomarkers [PDF]

, 2022
Zsüliet Kristóf, Mária Baranyi, Pál Tod, Paula Mut-Arbona, Kornél Demeter, István Bitter, Beáta Sperlágh   +6 more
openalex   +1 more source

Biological Characteristics of a Probiotic Wickerhamomyces anomalus Isolated from Pickled Vegetables and Its Function in Preventing Hyperuricemia in Mice

Foods
Hyperuricemia (HUA) is a metabolic disorder that can easily lead to gout or kidney disease, and it is believed that it can be treated effectively using probiotics.
Xiqian Tan, Shuaibo Gao, Xiaoxiao Cheng, Lijun You, Xuepeng Li, Jianrong Li   +5 more
doaj   +1 more source

Purine Phosphoribosyltransferases [PDF]

Journal of Biological Chemistry, 2000
S P, Craig, A E, Eakin
openaire   +2 more sources

Synthesis of purines and adenines containing the hexafluoroisopropyl group

Beilstein Journal of Organic Chemistry, 2020
Several new derivatives of adenine, purine, and theophylline containing the (CF3)2CH group connected to a nitrogen atom of the imidazole ring were prepared by the reaction of 2,2,4,4-tetrakis(trifluoromethyl)-1,3-dithietane (1) with the corresponding ...
Viacheslav Petrov, Rebecca J. Dooley, Alexander A. Marchione, Elizabeth L. Diaz, Brittany S. Clem, William Marshall   +5 more
doaj   +1 more source

Probiotics in Alleviating Hyperuricemia: Research Status, Mechanism of Action and Challenges

Shipin gongye ke-ji
Hyperuricemia (HUA) is a chronic metabolic disease, characterized by excessive uric acid in the blood, caused by purine metabolism disorders. Studies show that conventional clinical treatment methods have certain limitations, while probiotics have the ...
Xinru YANG, Jiayue TANG, Xiaoqun ZENG, Zhen WU, Qiwei DU, Maolin TU   +5 more
doaj   +1 more source

Synthesis, Antiproliferative Activity, and ADME Profiling of Novel Racemic and Optically Pure Aryl-Substituted Purines and Purine Bioisosteres

Biomolecules
The aim of this study was to synthesize new racemic and optically pure aryl-substituted purine bioisosteres using ultrasound-assisted Cu(I)-catalyzed Huisgen 1,3-dipolar cycloaddition.
Martina Piškor, Astrid Milić, Sanja Koštrun, Maja Majerić Elenkov, Petra Grbčić, Sandra Kraljević Pavelić, Krešimir Pavelić, Silvana Raić-Malić   +7 more
doaj   +1 more source

DNA Flap‐Mediated Control of Transcription for Programmable RNA Synthesis

Angewandte Chemie International Edition, EarlyView.
Pyrimidine‐rich ssDNA flaps on the T7 promoter inhibit T7 RNA polymerase (T7RP) transcription. Leveraging this pyrimidine bias, we developed DNAzyme‐ and MNAzyme‐mediated flap promoter induced transcription control (D‐FIT and M‐FIT) systems. These platforms enable regulated transcription and sequence‐specific detection, highlighting the programmable ...
Eun Sung Lee, Jisu Woo, Seokjoon Kim, Seok Hyeon Kim, Gun Haeng Lee, Ki Soo Park   +5 more
wiley   +1 more source

Probiotics administration alleviates cognitive impairment and circadian rhythm disturbance induced by sleep deprivation

Food Science and Human Wellness
Gut microbiome is indispensable for maintaining normal brain function. Specifically, gut microbiota plays a causal role in sleep deprivation (SD)-induced cognitive impairment.
Peijun Tian, Yunfei Hou, Zheng Wang, Jiaona Jiang, Xin Qian, Zhihao Qu, Jianxin Zhao, Gang Wang, Wei Chen   +8 more
doaj   +1 more source

The parallel accumulation and distribution of two purine-oxidizing enzymes during frog development [PDF]

, 2012
Dennis Barrett
openalex   +1 more source