Results 161 to 170 of about 28,518 (238)

An efficient transition metal-free indolylation on 6-chloropurine ribonucleosides and photophysical studies of conjugated nucleosides. [PDF]

RSC Adv
Mondal SK, Singh S, Pal S.
europepmc   +1 more source

Microbiome of Apical Intracanal and Extraradicular Biofilms From the Same Roots of Teeth With Persistent Apical Periodontitis: An Observational Study

International Endodontic Journal, EarlyView.
ABSTRACT Aim Bacterial biofilms around the apex are crucial in disease progression and persistence of apical periodontitis. While intracanal biofilms initiate infection, extraradicular biofilms contribute to treatment resistance and persistence. Thus, a comprehensive understanding of these biofilms may help elucidate mechanisms underlying persistent ...
Yoko Asahi, Nanako Kuriki, Motoki Okamoto, Daisuke Motooka, Shota Nakamura, Hazuki Maezono, Kittipit Klanliang, Tsuyoshi Shimaoka, Tetsuya Iida, Shigeyuki Ebisu, Yuichiro Noiri, Mikako Hayashi   +11 more
wiley   +1 more source

Development, anti-proliferative activity, multi-target kinase inhibition against CHK1, PIM1, and CDK-2, and computational insights of new thiazole-based hybrids. [PDF]

RSC Adv
Altwaijry NA, Othman IMM, Anwar MM, Nosier SS, Saleh A, Tashkandi NY, Nossier ES.   +6 more
europepmc   +1 more source

Untargeted Metabolomic and Lipidomic Profiles of Gingival Crevicular Fluid in the Context of Periodontitis

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aim(s) This cross‐sectional clinical study aimed to explore the untargeted metabolomic and lipidomic profiles in gingival crevicular fluid (GCF) obtained from healthy individuals and patients with periodontitis. Materials and Methods GCF was collected from 17 periodontally healthy and 19 periodontitis patients.
Caroline H. Henderzahs, Chiaki Yamada, Alexandr Morozov, Thelmalane Yalartai, Vanchit John, Hawra AlQallaf, Alexandru Movila   +6 more
wiley   +1 more source

One-Carbon Metabolism and Midbrain Dopaminergic Cells in Lesch-Nyhan Disease. [PDF]

Mol Syndromol
Alsuwaidi S, Ernst C.
europepmc   +1 more source

AlkaPlorer: A database‐driven explorer for natural alkaloids and derivatives

Journal of Integrative Plant Biology, EarlyView.
The alkaloid database AlkaPlorer integrates over 130,000 compounds across 12,250 species. By linking chemical structures with biological and evolutionary data, it reveals how these molecules evolve and function. This platform serves as a vital resource for AI‐driven discovery in plant metabolism and modern drug development. ABSTRACT Alkaloids, renowned
Jiahao Li, Tao Zeng, Hongquan Xu, Xu Kang, Minghui Liang, Ruibo Wu   +5 more
wiley   +1 more source

Bioactive Components, Untargeted Metabolomics and Bioinformatics of <i>Chaenomeles speciosa</i> Fruit on Uric Acid-Lowering Activity Assessment. [PDF]

Foods
Zhang M, Liu C, Zhang Y, Yuan Z, Chen S, Zhang H, Huang X, Chen L, Mei Z, Ge Y.   +9 more
europepmc   +1 more source

Asthma in Young Adults at High Risk for Allergies Is Traced Back to Immune and Microbiota Signatures in Early Childhood

Clinical &Experimental Allergy, EarlyView.
Ymke A. de Jong, Isabella Badolati, Ulrika Hellberg, Katarína Bankóová, Caroline Nilsson, Eva Sverremark‐Ekström   +5 more
wiley   +1 more source

Key metabolites secreted by Chlorella vulgaris alleviate salt stress in soybean seedlings

Journal of Integrative Plant Biology, EarlyView.
Chlorella vulgaris secretes exosome‐derived linolenic acid and inosine, which alleviate salt stress and enhance salt tolerance in soybean seedlings by activating stress‐responsive signaling networks. ABSTRACT Soil salinization is a major abiotic stress factor that reduces soybean production.
Yunyi Shi, Ruitong Chen, Kai Jiang, Aijuan Jiang, Jianchao Yang, Hongli Cui, Min Chen   +6 more
wiley   +1 more source