Results 81 to 90 of about 28,518 (238)

Urinary dynamics and analytical composition of neonatal Brown Swiss calves' urine during the first week postpartum, fed either dam's milk or milk replacer

open access: yesJournal of Dairy Science
: Monitoring urine composition is a valuable method for identifying metabolic disorders and diseases noninvasively. This study analyzed urination events, urine amounts, and urine composition in dairy calves during their first week of life, comparing ...
Anton M. Vorndran   +3 more
doaj   +1 more source

Synthesis of some novel hydrazono acyclic nucleoside analogues

open access: yesBeilstein Journal of Organic Chemistry, 2010
The syntheses of novel hydrazono acyclic nucleosides similar to miconazole scaffolds are described. In this series of acyclic nucleosides, pyrimidine as well as purine and other azole derivatives replaced the imidazole function in miconazole and the ...
Mohammad N. Soltani Rad   +2 more
doaj   +1 more source

Tissue‐specific and spatially dependent metabolic signatures perturbed by injury in male and female mice

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Osteoarthritis—the leading cause of disability worldwide—disproportionately affects females, yet sex remains an overlooked determinant. This disparity stems from sex‐specific differences in injury susceptibility—a major risk factor for disease.
Hope D. Welhaven   +6 more
wiley   +1 more source

CAQ Corner: Basic concepts of transplant immunology

open access: yes, 2022
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley   +1 more source

Beta-hydroxyphosphonate ribonucleoside analogues derived from 4-substituted-1,2,3-triazoles as IMP/GMP mimics: synthesis and biological evaluation

open access: yesBeilstein Journal of Organic Chemistry, 2016
A series of seventeen β-hydroxyphosphonate ribonucleoside analogues containing 4-substituted-1,2,3-triazoles was synthesized and fully characterized. Such compounds were designed as potential inhibitors of the cytosolic 5’-nucleotidase II (cN-II), an ...
Tai Nguyen Van   +7 more
doaj   +1 more source

5‐Methylcytosine Analysis of miRNAs in Minimal Change Disease

open access: yesBiotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Minimal change disease (MCD) is a glomerular disorder, which is the most common cause of nephrotic syndrome in children. Additionally, the prevalence of MCD in adults has been increasing in recent years. During protein synthesis, noncoding RNAs can be regulated through a variety of modifications, which helps preserve biological diversity and ...
Huiyi Zeng   +14 more
wiley   +1 more source

Novel Bis- and Mono-Pyrrolo[2,3-d]pyrimidine and Purine Derivatives: Synthesis, Computational Analysis and Antiproliferative Evaluation. [PDF]

open access: yesMolecules, 2021
Bistrović Popov A   +6 more
europepmc   +1 more source

Synthesis of Purine Derivatives from Glyoxalines.

open access: yes, 1934
Synthesis of Purine Derivatives from Glyoxalines.
P. C. MITTER, NRIPENDRA NATH CHATTERJEE
openaire   +1 more source

Effect of developmental changes on pharmacokinetics of drugs used in the treatment of infant acute lymphoblastic leukaemia—A comprehensive review

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis   +5 more
wiley   +1 more source

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