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Wnt/β-catenin signalling activates IMPDH2-mediated purine metabolism to facilitate oxaliplatin resistance by inhibiting caspase-dependent apoptosis in colorectal cancer. [PDF]
J Transl MedHuang Y +11 more
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FRUCTOSE AND PURINE METABOLISM
Acta Medica Scandinavica, 1972Abstract.The interactions between fructose and purine metabolism are reviewed. Hyperuricemia and increased production of uric acid after fructose administration have been documented in man as well as in the rat. These effects appear to be dependent on the rapid phosphorylation of fructose, mainly in the liver.
Pekka H. Mäenpää +2 more
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Purine Metabolism in Trypanosomatids*
The Journal of Protozoology, 1979SYNOPSIS. Purine nucleotide biosynthesis was studied in culture forms of Trypanosoma cruzi strain Y, Crithidia deanei (a reduviid trypanosomatid with an endosymbiote) and an aposymbiotic strain of C. deanei (obtained by curing C. deanei with chloramphenicol).
Isaac Roitman +4 more
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Biochemical Society Transactions, 1981
Abstract The inherited disorders of purine metabolism associated with renal disease are listed in Table 24.1. They are the sole cause of only a small proportion of all renal disease and are therefore best considered as part of the overall problem of purine, especially uric acid metabolism-related renal disease.
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Abstract The inherited disorders of purine metabolism associated with renal disease are listed in Table 24.1. They are the sole cause of only a small proportion of all renal disease and are therefore best considered as part of the overall problem of purine, especially uric acid metabolism-related renal disease.
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Metabolism of Purines and Pyrimidines
Annual Review of Biochemistry, 1956The emphasis of recent reviews on structural aspects of nucleic acid chem istry and the substantial achievement represented by the publications of the past year on the metabolism of purine and pyrimidine nucleotides has led to the selection of enzymic reactions operative in the synthesis of these com pounds as the principal subject of this review ...
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Purine Metabolism in Feline Lymphomas
Veterinary Pathology, 1990Deficiency of the purine metabolic enzyme adenosine deaminase causes severe immunodeficiency. Retroviruses have been reported to decrease the activity of adenosine deaminase, and many retroviruses, including feline leukemia virus, cause immunodeficiency.
S. C. Johnson +3 more
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Disorders of Purine Metabolism
1991Gout is a heterogeneous group of disorders of purine metabolism which leads to hyperuricemia and arthritis as well as gout nodules (tophi) from deposition of urate crystals in and around the joints and in the skin. The hyperuricemia in primary gout is related to overproduction or reduced renal excretion of uric acid, while in secondary gout it is due ...
Helmut H. Wolff +3 more
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