Results 31 to 40 of about 1,297,457 (342)

Rewiring of purine metabolism in response to acidosis stress in glioma stem cells

open access: yesCell Death and Disease, 2021
Glioma stem cells (GSCs) contribute to therapy resistance and poor outcomes for glioma patients. A significant feature of GSCs is their ability to grow in an acidic microenvironment.
Xiaoyu Xu   +11 more
semanticscholar   +1 more source

PECULIARITIES OF PURINE METABOLISM AND LIPID PEROXIDATION IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION

open access: yesРациональная фармакотерапия в кардиологии, 2016
Aim. To study purine metabolism and lipid peroxidation in patients with acute myocardial infarction with ST segment elevation (STEMI) in dependence on severity of acute heart failure (AHF). To evaluate effects of thrombolytic therapy on purine metabolism
E. V. Horolets   +3 more
doaj   +1 more source

Rhein modulates host purine metabolism in intestine through gut microbiota and ameliorates experimental colitis

open access: yesTheranostics, 2020
Background: Gut microbiota, which plays a crucial role in inflammatory bowel diseases (IBD), might have therapeutic benefits for ulcerative colitis or Crohn's disease. Targeting gut microbiota represents a new treatment strategy for IBD patients.
Jiawei Wu   +9 more
semanticscholar   +1 more source

The need for purine examination on fisherman

open access: yesJurnal Teknologi Laboratorium, 2021
The need for purine check on Fisherman is important because when the fisherman excess consuming highly purine contained in the food in a long rime periode will cause purine metabolism disorder and can lead to purine deposition  in  joint tissue and ...
Ketrina Konoralma   +5 more
doaj   +1 more source

Metabolism drives macrophage heterogeneity in the tumor microenvironment

open access: yesCell Reports, 2022
Summary: Tumor-associated macrophages (TAMs) are a major cellular component in the tumor microenvironment (TME). However, the relationship between the phenotype and metabolic pattern of TAMs remains poorly understood.
Shasha Li   +15 more
doaj   +1 more source

Features and relationships of metabolic syndrome components in men with androgen deficiency. Part 2. Disorders of carbohydrate and purine metabolism. Retrospective study data

open access: yesАкушерство, гинекология и репродукция, 2022
Introduction. Currently, few epidemiological data on a relation between impaired purine and carbohydrate metabolism and testosterone deficiency in overweight men due to adipose tissue and metabolic syndrome (MS) are available.Aim: to study relationships ...
Z. Sh. Pavlova, V. Yu. Grevina
doaj   +1 more source

Inborn Errors of Purine Salvage and Catabolism

open access: yesMetabolites, 2023
Cellular purine nucleotides derive mainly from de novo synthesis or nucleic acid turnover and, only marginally, from dietary intake. They are subjected to catabolism, eventually forming uric acid in humans, while bases and nucleosides may be converted ...
Marcella Camici   +6 more
doaj   +1 more source

Purine metabolism regulates Vibrio splendidus persistence associated with protein aggresome formation and intracellular tetracycline efflux

open access: yesFrontiers in Microbiology, 2023
A small subpopulation of Vibrio splendidus AJ01 that was exposed to tetracycline at 10 times the minimal inhibitory concentration (MIC) still survived, named tetracycline-induced persister cells in our previous work.
Yanan Li   +5 more
doaj   +1 more source

Purine and pyrimidine metabolism [PDF]

open access: yesProceedings of the Nutrition Society, 1982
The pathways of purine biosynthesis and degradation have been elucidated during the last 30 years; the regulation of the mechanisms involved is not yet fully understood, particularly with respect to quantitative aspects. Research into inborn errors of purine metabolism has provided valuable insights into purine synthesis and salvage pathways. Nutrition
openaire   +3 more sources

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