Results 31 to 40 of about 1,394,357 (370)
International Journal of Molecular Sciences, 2023 This present study was conducted to provide evidence and an explanation for the apoptosis that occurs in the marine rotifer Brachionus plicatilis when facing 2,2′,4,4′-tetrabromodiphenyl ether (BDE-47) stress.
Sai Cao +5 more
semanticscholar +1 more source
Evolutionary impacts of purine metabolism genes on mammalian oxidative stress adaptation
Zoological Research, 2022 Many mammals risk damage from oxidative stress stemming from frequent dives (i.e., cycles of ischemia/reperfusion and hypoxia/reoxygenation), high altitude and subterranean environments, or powered flight.
Ran Tian +5 more
semanticscholar +1 more source
Frontiers in Pharmacology, 2022 Glioma is the most common malignant tumor in the central nervous system. The impact of metabolism on cancer development and the immune microenvironment landscape has recently gained broad attention. Purines are involved in multiple metabolic pathways. It
Siliang Chen +10 more
semanticscholar +1 more source
Associations between purine metabolites and clinical symptoms in schizophrenia [PDF]
, 2012 Background: The antioxidant defense system, which is known to be dysregulated in schizophrenia, is closely linked to the dynamics of purine pathway. Thus, alterations in the homeostatic balance in the purine pathway may be involved in the pathophysiology
Debra M. Montrose +9 more
core +6 more sources
Frontiers in Bioscience-Landmark, 2023 Background: Metabolic reprogramming provides a new perspective for understanding cancer. The targeting of dysregulated metabolic pathways may help to reprogram the immune status of the tumor microenvironment (TME), thereby increasing the effectiveness of
Hui Liu +4 more
doaj +1 more source
New Phytologist, 2021 Ascospores generated during sexual reproduction are the primary inoculum for the wheat scab fungus Fusarium graminearum. Purine metabolism is known to play important roles in fungal pathogens but its lifecycle stage-specific regulation is unclear.
Manli Sun +9 more
semanticscholar +1 more source
Frontiers in Pharmacology, 2022 Graphical Abstract Bupleurum chinense DC (Chaihu)-Paeonia lactiflora Pall (Baishao) is among the most accepted herb pairs in many classic antidepressant prescriptions.
Jiajun Chen +4 more
semanticscholar +1 more source
Рациональная фармакотерапия в кардиологии, 2016 Aim. To study purine metabolism and lipid peroxidation in patients with acute myocardial infarction with ST segment elevation (STEMI) in dependence on severity of acute heart failure (AHF). To evaluate effects of thrombolytic therapy on purine metabolism
E. V. Horolets +3 more
doaj +1 more source
Altered purine metabolism at reperfusion affects clinical outcome in lung transplantation
Thorax, 2022 Introduction Lung transplantation is an established treatment for patients with end-stage lung disease. However, ischaemia reperfusion injury remains a barrier to achieving better survival outcomes.
C. Baciu +5 more
semanticscholar +1 more source
Biosensor measurement of purine release from cerebellar cultures and slices [PDF]
, 2010 We have previously described an action-potential and Ca2+-dependent form of adenosine release in the molecular layer of cerebellar slices. The most likely source of the adenosine is the parallel fibres, the axons of granule cells. Using microelectrode
Dale, Nicholas +2 more
core +3 more sources