Results 31 to 40 of about 1,319,221 (377)

DISORDERS OF PURIN METABOLISM [PDF]

open access: yesJournal of the American Medical Association, 1912
The old time term "uric acid diathesis" was an elastic expression, embracing such different conditions as gout, chronic rheumatism, uratic calculus, obesity and certain nephritides. In the light of more recent knowledge, the meaning of the term has been gradually narrowed until at the present time it includes only those diseases or clinical syndromes ...
Alfred C. Reed, George B. Wallace
openaire   +3 more sources

Pyrimidine biosynthesis is not an essential function for trypanosoma brucei bloodstream forms [PDF]

open access: yes, 2013
<p>Background: African trypanosomes are capable of both pyrimidine biosynthesis and salvage of preformed pyrimidines from the host, but it is unknown whether either process is essential to the parasite.</p> <p>Methodology/Principal ...
A Hofer   +51 more
core   +14 more sources

Rewiring of purine metabolism in response to acidosis stress in glioma stem cells

open access: yesCell Death and Disease, 2021
Glioma stem cells (GSCs) contribute to therapy resistance and poor outcomes for glioma patients. A significant feature of GSCs is their ability to grow in an acidic microenvironment.
Xiaoyu Xu   +11 more
semanticscholar   +1 more source

The need for purine examination on fisherman

open access: yesJurnal Teknologi Laboratorium, 2021
The need for purine check on Fisherman is important because when the fisherman excess consuming highly purine contained in the food in a long rime periode will cause purine metabolism disorder and can lead to purine deposition  in  joint tissue and ...
Ketrina Konoralma   +5 more
doaj   +1 more source

Anticipatory banking of samples enables diagnosis of adenylosuccinase deficiency following molecular autopsy in an infant with vacuolating leukoencephalopathy

open access: yesAmerican Journal of Medical Genetics Part A, Volume 191, Issue 1, Page 234-237, January 2023., 2023
Abstract Adenylosuccinase deficiency is a rare inborn error of metabolism. We present a newborn who died at 52 days of age with clinical features suggestive of severe epileptic encephalopathy and leukodystrophy of unknown cause. Post‐mortem examination showed an unusual vacuolar appearance of the brain.
Spatikha Sitaram   +11 more
wiley   +1 more source

PECULIARITIES OF PURINE METABOLISM AND LIPID PEROXIDATION IN PATIENTS WITH ACUTE MYOCARDIAL INFARCTION

open access: yesРациональная фармакотерапия в кардиологии, 2016
Aim. To study purine metabolism and lipid peroxidation in patients with acute myocardial infarction with ST segment elevation (STEMI) in dependence on severity of acute heart failure (AHF). To evaluate effects of thrombolytic therapy on purine metabolism
E. V. Horolets   +3 more
doaj   +1 more source

Metabolic engineering of the purine biosynthetic pathway in Corynebacterium glutamicum results in increased intracellular pool sizes of IMP and hypoxanthine [PDF]

open access: yes, 2012
Background: Purine nucleotides exhibit various functions in cellular metabolism. Besides serving as building blocks for nucleic acid synthesis, they participate in signaling pathways and energy metabolism.
Barduhn, Tobias   +5 more
core   +1 more source

Rhein modulates host purine metabolism in intestine through gut microbiota and ameliorates experimental colitis

open access: yesTheranostics, 2020
Background: Gut microbiota, which plays a crucial role in inflammatory bowel diseases (IBD), might have therapeutic benefits for ulcerative colitis or Crohn's disease. Targeting gut microbiota represents a new treatment strategy for IBD patients.
Jiawei Wu   +9 more
semanticscholar   +1 more source

Features and relationships of metabolic syndrome components in men with androgen deficiency. Part 2. Disorders of carbohydrate and purine metabolism. Retrospective study data

open access: yesАкушерство, гинекология и репродукция, 2022
Introduction. Currently, few epidemiological data on a relation between impaired purine and carbohydrate metabolism and testosterone deficiency in overweight men due to adipose tissue and metabolic syndrome (MS) are available.Aim: to study relationships ...
Z. Sh. Pavlova, V. Yu. Grevina
doaj   +1 more source

Purine synthesis promotes maintenance of brain tumor initiating cells in glioma [PDF]

open access: yes, 2018
Brain tumor initiating cells (BTICs), also known as cancer stem cells, hijack high-affinity glucose uptake active normally in neurons to maintain energy demands.
Bao, Shideng   +21 more
core   +1 more source

Home - About - Disclaimer - Privacy