Results 31 to 40 of about 1,276,502 (363)
Rewiring of purine metabolism in response to acidosis stress in glioma stem cells
Cell Death and Disease, 2021 Glioma stem cells (GSCs) contribute to therapy resistance and poor outcomes for glioma patients. A significant feature of GSCs is their ability to grow in an acidic microenvironment.
Xiaoyu Xu +11 more
semanticscholar +1 more source
American Journal of Medical Genetics Part A, Volume 191, Issue 1, Page 234-237, January 2023., 2023 Abstract Adenylosuccinase deficiency is a rare inborn error of metabolism. We present a newborn who died at 52 days of age with clinical features suggestive of severe epileptic encephalopathy and leukodystrophy of unknown cause. Post‐mortem examination showed an unusual vacuolar appearance of the brain.
Spatikha Sitaram +11 more
wiley +1 more source
The need for purine examination on fisherman
Jurnal Teknologi Laboratorium, 2021 The need for purine check on Fisherman is important because when the fisherman excess consuming highly purine contained in the food in a long rime periode will cause purine metabolism disorder and can lead to purine deposition in joint tissue and ...
Ketrina Konoralma +5 more
doaj +1 more source
Рациональная фармакотерапия в кардиологии, 2016 Aim. To study purine metabolism and lipid peroxidation in patients with acute myocardial infarction with ST segment elevation (STEMI) in dependence on severity of acute heart failure (AHF). To evaluate effects of thrombolytic therapy on purine metabolism
E. V. Horolets +3 more
doaj +1 more source
Theranostics, 2020 Background: Gut microbiota, which plays a crucial role in inflammatory bowel diseases (IBD), might have therapeutic benefits for ulcerative colitis or Crohn's disease. Targeting gut microbiota represents a new treatment strategy for IBD patients.
Jiawei Wu +9 more
semanticscholar +1 more source
Акушерство, гинекология и репродукция, 2022 Introduction. Currently, few epidemiological data on a relation between impaired purine and carbohydrate metabolism and testosterone deficiency in overweight men due to adipose tissue and metabolic syndrome (MS) are available.Aim: to study relationships ...
Z. Sh. Pavlova, V. Yu. Grevina
doaj +1 more source
Universal scaling relation and criticality in metabolism and growth of Escherichia coli [PDF]
Phys. Rev. Research 6, 013035 (2024), 2023 The metabolic network plays a crucial role in regulating bacterial metabolism and growth, but it is subject to inherent molecular stochasticity. Previous studies have utilized flux balance analysis and the maximum entropy method to predict metabolic fluxes and growth rates, while the underlying principles governing bacterial metabolism and growth ...
arxiv +1 more source
Inborn Errors of Purine Salvage and Catabolism
Metabolites, 2023 Cellular purine nucleotides derive mainly from de novo synthesis or nucleic acid turnover and, only marginally, from dietary intake. They are subjected to catabolism, eventually forming uric acid in humans, while bases and nucleosides may be converted ...
Marcella Camici +6 more
doaj +1 more source
Contributing Components of Metabolic Energy Models to Metabolic Cost Estimations in Gait [PDF]
, 2023 Objective: As metabolic cost is a primary factor influencing humans' gait, we want to deepen our understanding of metabolic energy expenditure models. Therefore, this paper identifies the parameters and input variables, such as muscle or joint states, that contribute to accurate metabolic cost estimations.
arxiv +1 more source
Linear Response Theory of Evolved Metabolic Systems [PDF]
, 2022 Predicting cellular metabolic states is a central problem in biophysics. Conventional approaches, however, sensitively depend on the microscopic details of individual metabolic systems. In this Letter, we derived a universal linear relationship between the metabolic responses against nutrient conditions and metabolic inhibition, with the aid of a ...
arxiv +1 more source