Results 101 to 110 of about 6,269 (168)

Purine nucleoside phosphorylase inhibition is an effective approach for the treatment of chemical hemorrhagic cystitis. [PDF]

JCI Insight
Wolf-Johnston A, Ikeda Y, Zabbarova I, Kanai AJ, Bastacky S, Moldwin R, Stern JN, Jackson EK, Birder LA.   +8 more
europepmc   +1 more source

The use of Trichomonas vaginalis purine nucleoside phosphorylase to activate fludarabine in the treatment of solid tumors. [PDF]

Cancer Chemother Pharmacol, 2020
Parker WB, Allan PW, Waud WR, Hong J, Gilbert-Ross M, Achyut BR, Joshi D, Behbahani T, Rab R, Ealick SE, Sorscher EJ.   +10 more
europepmc   +1 more source

Identification and structural validation of purine nucleoside phosphorylase from Plasmodium falciparum as a target of MMV000848. [PDF]

J Biol Chem
Chung Z, Lin J, Wirjanata G, Dziekan JM, El Sahili A, Preiser PR, Bozdech Z, Lescar J.   +7 more
europepmc   +1 more source

Hematopoietic stem cell transplantation for purine nucleoside phosphorylase deficiency: an EBMT-IEWP retrospective study.

Blood
Herrmann US, Felber M, Worth A, Haskologlu S, Dogu F, Lewis VA, Strahm B, Groll A, Gennery AR, Hauck F, Wynn R, Coussons M, Meyts I, Lindemans C, Bordon V, Bredius RGM, Kühl JS, Völler M, Zirngibl F, Zaidman I, Laberko A, Zeilhofer U, Hauri-Hohl M, Lankester A, Ikinciogullari A, Guilcher GMT, Hackenberg A, Yeşilipek A, Davies G, Rao K, Hershfield MS, Parikh SH, Gilbert P, Bettoni da Cunha Riehm C, Albert MH, Schulz AS, Hönig M, Neven B, Güngör T.   +38 more
europepmc   +1 more source

Characterization of the N⁶-etheno-bridge method to assess extracellular metabolism of adenine nucleotides: detection of a possible role for purine nucleoside phosphorylase in adenosine metabolism. [PDF]

Purinergic Signal, 2020
Jackson EK, Gillespie DG, Cheng D, Mi Z, Menshikova EV.   +4 more
europepmc   +1 more source

Recurrent infections, neurologic signs, low serum uric acid levels, and lymphopenia in childhood: Purine nucleoside phosphorylase deficiency, an emergency for infants. [PDF]

Turk Pediatri Ars, 2020
Kütükçüler N, Bölük E, Tökmeci N, Karaca NE, Azarsız E, Aksu G, Aykut A.   +6 more
europepmc   +1 more source

Genetic resistance to purine nucleoside phosphorylase inhibition in Plasmodium falciparum. [PDF]

Proc Natl Acad Sci U S A, 2018
Ducati RG, Namanja-Magliano HA, Harijan RK, Fajardo JE, Fiser A, Daily JP, Schramm VL.   +6 more
europepmc   +1 more source

Crystal structure of Escherichia coli purine nucleoside phosphorylase complexed with acyclovir. [PDF]

Acta Crystallogr F Struct Biol Commun, 2018
Timofeev VI, Zhukhlistova NE, Abramchik YA, Muravieva TI, Esipov RS, Kuranova IP.   +5 more
europepmc   +1 more source

Crystal structure of Escherichia coli purine nucleoside phosphorylase in complex with 7-deazahypoxanthine. [PDF]

Acta Crystallogr F Struct Biol Commun, 2018
Timofeev VI, Zhukhlistova NE, Abramchik YA, Fateev II, Kostromina MA, Muravieva TI, Esipov RS, Kuranova IP.   +7 more
europepmc   +1 more source

An unusual presentation of purine nucleoside phosphorylase deficiency mimicking systemic juvenile idiopathic arthritis complicated by macrophage activation syndrome. [PDF]

Pediatr Rheumatol Online J, 2019
Arduini A, Marasco E, Marucci G, Pardeo M, Insalaco A, Caiello I, Moneta GM, Prencipe G, De Benedetti F, Bracaglia C.   +9 more
europepmc   +1 more source