Results 191 to 200 of about 25,696 (291)

Interaction of Tri-Cyclic Nucleobase Analogs with Enzymes of Purine Metabolism: Xanthine Oxidase and Purine Nucleoside Phosphorylase. [PDF]

Int J Mol Sci
Stachelska-Wierzchowska A, Narczyk M, Wierzchowski J, Bzowska A, Wielgus-Kutrowska B.   +4 more
europepmc   +1 more source

Crystal structure of calf spleen purine nucleoside phosphorylase complexed to a novel purine analogue [PDF]

, 2007
H.M. Pereira, Valério Berdini, Anne Cleasby, Richard Charles Garratt   +3 more
openalex   +1 more source

Purine nucleoside phosphorylase inhibition is an effective approach for the treatment of chemical hemorrhagic cystitis. [PDF]

JCI Insight
Wolf-Johnston A, Ikeda Y, Zabbarova I, Kanai AJ, Bastacky S, Moldwin R, Stern JN, Jackson EK, Birder LA.   +8 more
europepmc   +1 more source

The use of Trichomonas vaginalis purine nucleoside phosphorylase to activate fludarabine in the treatment of solid tumors. [PDF]

Cancer Chemother Pharmacol, 2020
Parker WB, Allan PW, Waud WR, Hong J, Gilbert-Ross M, Achyut BR, Joshi D, Behbahani T, Rab R, Ealick SE, Sorscher EJ.   +10 more
europepmc   +1 more source

Immucillin H, a powerful transition-state analog inhibitor of purine nucleoside phosphorylase, selectively inhibits human T lymphocytes

, 2001
Greg A. Kicska, Long Li, Heidi Hörig, Craig R. Fairchild, Peter C. Tyler, Richard H. Furneaux, Vern L. Schramm, Howard L. Kaufman   +7 more
openalex   +1 more source

Remote Mutations and Active Site Dynamics Correlate with Catalytic Properties of Purine Nucleoside Phosphorylase [PDF]

, 2008
Suwipa Saen‐oon, Mahmoud Ghanem, Vern L. Schramm, Steven D. Schwartz   +3 more
openalex   +1 more source

On the analysis of fluorimetric titration curves of purine nucleoside phosphorylase [PDF]

, 2008
Jan Antosiewicz, Katarzyna Breer, Agnieszka Bzowska, Beata Wielgus‐Kutrowska   +3 more
openalex   +1 more source

Phase I dose-escalating trial of Escherichia coli purine nucleoside phosphorylase and fludarabine gene therapy for advanced solid tumors.

Annals of Oncology, 2015
E. Rosenthal, T. Chung, W. Parker, P. Allan, L. Clemons, Deborah Lowman, Jeong S. Hong, F. R. Hunt, J. Richman, R. Conry, K. Mannion, W. Carroll, L. Nabell, E. Sorscher   +13 more
semanticscholar   +1 more source

Third-Generation Immucillins: Syntheses and Bioactivities of Acyclic Immucillin Inhibitors of Human Purine Nucleoside Phosphorylase [PDF]

, 2009
Keith Clinch, Gary B. Evans, Richard Fröhlich, Richard H. Furneaux, Peter M. Kelly, Laurent Legentil, Andrew S. Murkin, Lei Li, Vern L. Schramm, Peter C. Tyler, Anthony D. Woolhouse   +10 more
openalex   +1 more source

Isotope-specific and amino acid-specific heavy atom substitutions alter barrier crossing in human purine nucleoside phosphorylase

Proceedings of the National Academy of Sciences of the United States of America, 2015
Javier Suárez, V. Schramm
semanticscholar   +1 more source