Results 111 to 120 of about 78,151 (289)

Sequence-specific Solution Structures of the Four Isosequential Pairs of Single-stranded DNAs and RNAs [PDF]

, 2008
The role of the sequence-context in the self-organization of four single-stranded (ss) isosequential pairs of DNAs (1 – 4) and RNAs (5 – 8), [d/r-(5'C^1^A^2^X^3^G^4^Y^5^A^6^C^7^): X^3^ = A or C, Y^5^ = A or C; sequence variations: 2^2^
Jyoti Chattopadhyaya, Subhrangsu Chatterjee, Wimal Pathmasiri   +2 more
core   +1 more source

DNA viewed as an out-of-equilibrium structure

, 2013
The complexity of the primary structure of human DNA is explored using methods from nonequilibrium statistical mechanics, dynamical systems theory and information theory.
Nicolis, C., Nicolis, G., Provata, A.
core   +1 more source

Rewiring nutrition: Chemical insights into the physiological and microbiological roles of food's microconstituents

Food Biomacromolecules, EarlyView.
Bidirectional interactions between food‐derived sensory compounds, gut sensing and microbiota, host physiological feedback, and metabolite production within the food matrix collectively shape sensory perception, microbial dynamics, and metabolic health.
Mohammad Nazrul Islam Bhuiyan
wiley   +1 more source

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source

Disruption of nucleotide biosynthesis reprograms mitochondrial metabolism to inhibit adipogenesis

Journal of Lipid Research
A key organismal response to overnutrition involves the development of new adipocytes through the process of adipogenesis. Preadipocytes sense changes in the systemic nutrient status and metabolites can directly modulate adipogenesis.
Julia A. Pinette, Jacob W. Myers, Woo Yong Park, Heather G. Bryant, Alex M. Eddie, Genesis A. Wilson, Claudia Montufar, Zayedali Shaikh, Zer Vue, Elizabeth R. Nunn, Ryoichi Bessho, Matthew A. Cottam, Volker H. Haase, Antentor O. Hinton, Jessica B. Spinelli, Jean-Philippe Cartailler, Elma Zaganjor   +16 more
doaj   +1 more source

An Interpretation of the Ancestral Codon from Miller's Amino Acids and Nucleotide Correlations in Modern Coding Sequences

Bioinformatics and Biology Insights, 2015
Purine bias, which is usually referred to as an “ancestral codon”, is known to result in short-range correlations between nucleotides in coding sequences, and it is common in all species.
Nicolas Carels, Miguel Ponce de Leon
doaj   +1 more source

Diagnosis and epidemiology of red blood cell enzyme disorders

Thalassemia Reports, 2013
The red blood cell possess an active metabolic machinery that provides the cell with energy to pump ions against electrochemical gradients, to maintain its shape, to keep hemoglobin iron in the reduced (ferrous) form, and to maintain enzyme and ...
Richard Van Wijk
doaj   +1 more source

Metabolomic and lipidomic signatures of Helicobacter pylori infection: Unveiling biochemical pathways associated with neurodegeneration

iMetaOmics, EarlyView.
Our study employed an integrated lipidomics and metabolomics approach to elucidate Helicobacter pylori‐driven metabolic perturbations along the gut–brain axis. H. pylori infection was established in gastric epithelial (AGS) cells, and the resulting conditioned media (secretome) was collected and exposed to neuronal (IMR‐32) cells.
Meenakshi Kandpal, Tarun Prakash Verma, Siddharth Singh, Hamendra Parmar, Hem Chandra Jha   +4 more
wiley   +1 more source

Purinosomes involved in the regulation of tumor metabolism: current progress and potential application targets

Frontiers in Oncology
The core of tumor cell metabolism is the management of energy metabolism due to the extremely high energy requirements of tumor cells. The purine nucleotide synthesis pathway in cells uses the purinosomes as an essential spatial structural complex.
Jiaqi Xie, Jiaqi Xie, Jiaqi Liu, Jiaqi Liu, Xiehui Chen, Changchun Zeng   +5 more
doaj   +1 more source

Comparative genomic analysis reveals a critical role of de novo nucleotide biosynthesis for Saccharomyces cerevisiae virulence.

PLoS ONE, 2015
In recent years, the number of human infection cases produced by the food related species Saccharomyces cerevisiae has increased. Whereas many strains of this species are considered safe, other 'opportunistic' strains show a high degree of potential ...
Roberto Pérez-Torrado, Silvia Llopis, Benedetta Perrone, Rocío Gómez-Pastor, Bernhard Hube, Amparo Querol   +5 more
doaj   +1 more source