Results 141 to 150 of about 7,481 (163)

P2-purinergic receptor antagonists reduce the minimum alveolar concentration of inhaled volatile anesthetics

open access: closedBrain Research, 2000
In the central nervous system (CNS), adenosine triphosphate (ATP) is reported to serve as a fast excitatory neurotransmitter via P2X receptor. To examine possible involvement of inhibition of ATP signal-transmission in anesthetic mechanism, the effect of intracerebroventricular (ICV) administration of P2 receptor antagonists on the minimum alveolar ...
E, Masaki   +5 more
openaire   +3 more sources

The purinergic P2 receptor antagonist pyridoxalphosphate-6-azophenyl-2'4’-disulphonic acid prevents both the acute locomotor effects of amphetamine and the behavioural sensitization caused by repeated amphetamine injections in rats

open access: closedNeuroscience, 2001
Repeated administration of amphetamine-like psychostimulants produce a progressive and long-lasting hypersensitivity to their behavioural effects known as behavioural sensitization. Previous studies have shown that administration of the purinergic P2 receptor agonist 2-methylthio ATP into the nucleus accumbens of rats raises the extracellular level of ...
H, Kittner, U, Krügel, P, Illes
openaire   +3 more sources

Comparison of the effects of apamin, a Ca2+-dependent K+ channel blocker, and arylazido aminopropionyl ATP (ANAPP3), a P2-purinergic receptor antagonist, in the guinea-pig vas deferens

open access: closedEuropean Journal of Pharmacology, 1984
Apamin, which blocks Ca2+-dependent increases in K+ permeability, antagonizes ATP-induced relaxation of several smooth muscles. The ATP photoaffinity label arylazido aminopropionyl ATP (ANAPP3), following its photolysis in the presence of the guinea-pig vas deferens, antagonizes contractile responses to ATP.
J S, Fedan   +2 more
openaire   +3 more sources
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