Release of ATP and glutamate in the nucleus tractus solitarii mediate pulmonary stretch receptor (Breuer-Hering) reflex pathway [PDF]
, 2008 The Breuer-Hering inflation reflex is initiated by activation of the slowly adapting pulmonary stretch receptor afferents (SARs), which monosynaptically activate second-order relay neurones in the dorsal medullary nucleus of the solitary tract (NTS ...
Enrique Llaudet +13 more
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New insights into purinergic receptor signaling in neuronal differentiation, neuroprotection, and brain disorders [PDF]
, 2007 Ionotropic P2X and metabotropic P2Y purinergic receptors are expressed in the central nervous system and participate in the synaptic process particularly associated with acetylcholine, GABA, and glutamate neurotransmission. As a result of activation, the
Trujillo, Cleber Augusto +15 more
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Mouse Leydig cells express multiple P2X receptor subunits
, 2008 ATP acts on cellular membranes by interacting with P2X (ionotropic) and P2Y (metabotropic) receptors. Seven homomeric P2X receptors (P2X(1)-P2X(7)) and seven heteromeric receptors (P2X(1/2), P2X(1/4), P2X(1/5), P2X(2/3), P2X(2/6), P2X(4/6), P2X(4/7 ...
Ligia Subitoni Antonio +7 more
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Binding thermodynamic characterization of human P2X1 and P2X3 purinergic receptors
, 2008 The present study was designed to perform binding and thermodynamic characterization of human P2X(1) and P2X(3) purinergic receptors expressed in HEK 293 cells.
TOSI, ALICE +6 more
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Erratum to: Purinergic P2X7 receptors regulate secretion of interleukin-1 receptor antagonist and beta cell function and survival [PDF]
Diabetologia, 2015 Glas, R. +5 more
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P2X7 Receptor Modulation of Visual Responses in the Retina [PDF]
, 2015 Adenosine 5’ triphosphate (ATP)-gated P2X7 receptors (P2X7Rs) are known to act as conduits for photoreceptor and retinal ganglion cell (RGC) damage, consequences of various neurodegenerative conditions within the visual pathway. Growing evidence supports
Chavda, S
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Investigation on 2′,3′-O-Substituted ATP Derivatives and Analogs as Novel P2X3 Receptor Antagonists [PDF]
, 2018 Antagonists of the purinergic P2X3 receptors represent promising drugs for the treatment of inflammation and pain. The ATP derivative 2′,3′-O-(2,4,6-trinitrophenyl)-ATP (TNP-ATP) has been described as a potent competitive inhibitor of this receptor.
Lambertucci, Catia +19 more
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, 2009 Udgivelsesdato: 2009-MarEscherichia coli is the dominant facultative bacterium in the normal intestinal flora. E. coli is, however, also responsible for the majority of serious extraintestinal infections.
J. Leipziger +7 more
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Purinergic Signalling and Neurological Diseases: An Update [PDF]
, 2017 Purinergic signalling, i.e. ATP as an extracellular signalling molecule and cotransmitter in both peripheral and central neurons, is involved in the physiology of neurotransmission and neuromodulation.
Geoffrey Burnstock, Burnstock, G
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Detection of P2X purinergic receptors on human B lymphocytes
, 2001 B lymphocytes are known to synthesise the P2X(7) subtype of the P2X purinergic receptor family; however, the identification of the other six P2X subtypes on these cells has been limited by the absence of specific antibodies.
James Wiley (238948) +2 more
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