Results 101 to 110 of about 44,347 (208)

Targeting Connexin 43 in Retinal Astrocytes Promotes Neuronal Survival in Glaucomatous Injury

open access: yesGlia, Volume 73, Issue 7, Page 1398-1419, July 2025.
Main Points Astrocytes play an important role in glaucoma. These cells express Cx43 which can form gap junctions and hemichannels. This study shows Cx43 deletion in astrocytes provides neuroprotection in glaucoma, possibly through hemichannel activation.
Khulan Batsuuri   +4 more
wiley   +1 more source

Potassium‐Dependent Coupling of Retinal Astrocyte Light Response to Müller Glia

open access: yesGlia, Volume 73, Issue 7, Page 1520-1534, July 2025.
Main Points Astrocytes depolarize to light ON and OFF like Müller glia. The astrocyte light response is due to potassium influx. Retinal macroglial current‐voltage responses exhibit rectification which changes with repeated stimulation. ABSTRACT Astrocytes throughout the central nervous system mediate a variety of functions to support proper tissue ...
Joseph Matthew Holden   +3 more
wiley   +1 more source

ROLE OF PURINERGIC RECEPTORS IN IMMUNE RESPONSE

open access: yesJournal of microbiology, epidemiology and immunobiology, 2016
Purine receptors are located on immune and somatic cells of animal and human organisms. Summation of signals from purine and TOLL-like receptors takes place on the level of inflammasome formation and results in summation of the first and second signals of innate immunity.
openaire   +5 more sources

The Role of Microglial Purinergic Receptors in Pain Signaling. [PDF]

open access: yesMolecules, 2022
Tozaki-Saitoh H, Takeda H, Inoue K.
europepmc   +1 more source

Investigating the Mechanism of Conditioning Versus Postoperative Electrical Stimulation to Enhance Nerve Regeneration: One Therapy, Two Distinct Effects

open access: yesMuscle &Nerve, Volume 72, Issue 1, Page 15-33, July 2025.
ABSTRACT Regeneration after peripheral nerve injury is often insufficient for functional recovery. Postoperative electrical stimulation (PES) following injury and repair significantly improves clinical outcomes; recently, conditioning electrical stimulation (CES), delivered before nerve injury, has been introduced as a candidate for clinical ...
Paige B. Hardy   +4 more
wiley   +1 more source

P2Y14 receptor activation of platelets induces Ca2+ mobilization and Rho‐GTPase‐dependent motility that requires an interaction with P2Y1 receptors

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 13, Page 2950-2967, July 2025.
Background and Purpose Platelet function during inflammation is dependent on activation by endogenous nucleotides acting on purinergic receptors. The P2Y14 receptor has been reported to be expressed on platelets and is involved in leukocyte recruitment during inflammation.
Md Monir Hossain   +6 more
wiley   +1 more source

Terpene Hydroperoxides as Lipid Peroxidation Inducers: Biomimetic and HaCaT Cell Studies in Allergic Contact Dermatitis

open access: yesContact Dermatitis, Volume 93, Issue 1, Page 16-30, July 2025.
Fragrance terpene hydroperoxides from limonene, linalool, and geraniol induced the formation of lipid peroxidation products when incubated with PLPC liposomes or in vitro with HaCaT keratinocytes. Lipid peroxidation products included aldehydes, ketones, and hydroperoxides.
Aaron I. Moore   +6 more
wiley   +1 more source

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