Results 111 to 120 of about 35,200 (254)

Proteolysis at the extracellular matrix interface: Molecular architects and regulators in health and disease

open access: yesThe FEBS Journal, EarlyView.
The extracellular matrix (ECM) is a dynamic scaffold that orchestrates tissue architecture and cellular communication. A critical but underexplored interplay between proteases and cluster of differentiation molecules (CD) governs ECM turnover and directs cell fate.
David Jurnečka   +3 more
wiley   +1 more source

Lifestyle triggers of migraine: Sleep restriction and caffeine lower the threshold for migraine‐like responses in rats in a sex‐specific manner

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Sleep restriction (SR) and caffeine intake act as environmental modulators of migraine susceptibility. Their effects are sex‐dependent: Females show heightened sensitivity under both SR and caffeine conditions. Males require the combination of SR and caffeine to exhibit susceptibility.
Gabriel Camargo de Oliveira   +7 more
wiley   +1 more source

Purinergic receptor expression in neuronal, bladder smooth muscle and urothelial cells: characterization and inhibition by low molecular weight antagonists

open access: yes, 2009
P2 purinoceptors comprise ionotropic (P2X) and metabotropic (P2Y) receptor families, responsive to nucleotide ligands and diversely distributed on virtually every mammalian cell. Most cells and tissues co-express multiple subtypes of purinoceptor; thus,
Gever, J.L.
core  

Possible neuroprotective role of P2X2 in the retina of diabetic rats

open access: yesDiabetology & Metabolic Syndrome, 2018
Background Purinergic receptors are expressed in different tissues including the retina. These receptors are involved in processes like cell growth, proliferation, activation and survival. ATP is the major activator of P2 receptors. In diabetes, there is
Jorge E. Mancini   +6 more
doaj   +1 more source

The Role of Neuropeptide Y in Dental Pulp: Balancing Neurogenic Inflammation and Pain Modulation

open access: yesInternational Endodontic Journal, EarlyView.
ABSTRACT Background Dental pulp is a densely innervated, low‐compliance tissue in which neurogenic inflammation can rapidly escalate into oedema, raised intrapulpal pressure, microvascular compromise, and pain. While Substance P (SP) and Calcitonin gene‐related peptide (CGRP) are well‐established drivers of pulp vasodilation, the Neuroopeptide Y (NPY ...
Javier Caviedes‐Bucheli   +3 more
wiley   +1 more source

Purinergic receptors expressed in human skeletal muscle fibres

open access: yes, 2011
Purinergic receptors are present in most tissues and thought to be involved in various signalling pathways, including neural signalling, cell metabolism and local regulation of the microcirculation in skeletal muscles. The present study aims to determine
A. Bornø   +9 more
core   +1 more source

Postnatal developmental changes in the laryngeal chemosensory cell clusters of rats

open access: yesJournal of Anatomy, EarlyView.
Chemosensory cell clusters appeared in the rat larynx 2 days after birth and were already connected to afferent nerve fibers. Their number increased until 3 weeks of age, then stabilized while continuing to grow through the addition of new cells. Because their number reached a plateau around the time of weaning, their development may be linked to ...
Sayed Sharif Abdali   +5 more
wiley   +1 more source

Purinergic receptors [PDF]

open access: yesTrends in Pharmacological Sciences, 1982
Scrutton, M.C., Burnstock, G.
openaire   +2 more sources

Peri‐Implantitis and Periodontitis: Biological Convergence, Contextual Divergence

open access: yesJournal of Periodontal Research, EarlyView.
Periodontal and peri‐implant tissues differ and coincide in many aspects, from the clinical and radiological perspective, including histology, microbiology, and molecular markers. Thus, health and disease may also follow different and similar routes.
Pablo Galindo‐Moreno   +6 more
wiley   +1 more source

Purinergic receptors and the inflammatory response mediated by lipids.

open access: yes, 2019
The inflammatory response is regulated by the production of different extracellular mediators, including lipids and extracellular nucleotides. In the extracellular environment, intermediate lipids activate specific G-protein-coupled receptors (GPCRs) in ...
Pelegrín, Pablo   +2 more
core   +1 more source

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