Results 181 to 190 of about 2,313,736 (322)

Transcriptomic profiling of dorsal root ganglia in atopic and healthy dogs: A comparative RNA sequencing study with implications in cutaneous itch research

Veterinary Dermatology, Volume 36, Issue 4, Page 401-411, August 2025.
Background – Itch is a common symptom in skin disorders. While the neural pathways of itch transmission from the skin to the brain are well‐understood in rodents, the same pathways in dogs remain unclear. The knowledge gap hinders the development of effective treatments for canine itch‐related disorders.
Chie Tamamoto‐Mochizuki, Santosh K. Mishra   +1 more
wiley   +1 more source

A novel pathway for the activation of phospholipase D by P2z purinergic receptors in BAC1.2F5 macrophages.

, 1992
Chakib El-Moatassim, George Dubyak
openalex   +1 more source

Expression and Regulation of P2U-Purinergic Receptor in Human Granulosa-Luteal Cells1 [PDF]

, 2000
Chen‐Jei Tai, Sung Keun Kang, Kwai Wa Cheng, Kyung‐Chul Choi, Parimal S. Nathwani, Peter C. K. Leung   +5 more
openalex   +1 more source

Non‐ionotropic NMDAR signalling activates Panx1 to induce P2X4R‐dependent long‐term depression in the hippocampus

The Journal of Physiology, Volume 603, Issue 15, Page 4367-4381, 1 August 2025.
Abstract figure legend Stimulation of the Shaffer collateral pathway at 3 Hz activates non‐ionotropic NMDA receptors. This subsequently leads to Src kinase mediated phosphorylation of pannexin‐1 (Panx1), which releases ATP from the postsynaptic cell. ATP acts as a ligand for P2X4 receptors to induce long‐term depression (LTD). Abstract In recent years,
Allison C. Nielsen, Connor L. Anderson, Carina Ens, Andrew K. J. Boyce, Roger J. Thompson   +4 more
wiley   +1 more source

Anti-Inflammatory Activity of 1,4-Naphthoquinones Blocking P2X7 Purinergic Receptors in RAW 264.7 Macrophage Cells. [PDF]

Toxins (Basel), 2023
Kozlovskiy SA, Pislyagin EA, Menchinskaya ES, Chingizova EA, Sabutski YE, Polonik SG, Likhatskaya GN, Aminin DL.   +7 more
europepmc   +1 more source

Characterization of the purinergic P2 receptors in PC12 cells. Evidence for a novel subtype.

, 1994
W.K. Kim, R.A. Rabin
openalex   +1 more source

Recent advances in the structure, function and regulation of the volume‐regulated anion channels and their role in immunity

The Journal of Physiology, Volume 603, Issue 15, Page 4255-4291, 1 August 2025.
Abstract figure legend The volume‐regulated anion channel (VRAC), composed of leucine‐rich repeat‐containing 8 (LRRC8) proteins, serves both canonical and non‐canonical functions in vertebrate cells. The canonical function of this channel relates to its original description, which is homeostatic regulation of cell volume in response to hypotonic ...
Sergei Yanushkevich, Aleksandra Zieminska, Joshua Gonzalez, Francisca Añazco, Richard Song, Alejandra Arias‐Cavieres, Sara T. Granados, Junyi Zou, Yan Rao, Axel R. Concepcion   +9 more
wiley   +1 more source

P2X₃ Knock-Out Mice Reveal a Major Sensory Role for Urothelially Released ATP [PDF]

, 2001
The present study explores the possible involvement of a purinergic mechanism in mechanosensory transduction in the bladder using P2X₃ receptor knock-out (P2X₃ ⁻⁄⁻) and wild-type control (P2X₃ ⁺⁄⁺) mice.
Bardini, M, Bodin, P, Burnstock, G, Cockayne, DA, Ford, APDW, Kasakov, L, Rong, W, Vlaskovska, M   +7 more
core  

Purinergic Receptors P2X7 and P2X4 as Markers of Disease Progression in the rd10 Mouse Model of Inherited Retinal Dystrophy. [PDF]

Int J Mol Sci, 2022
Martínez-Gil N, Kutsyr O, Noailles A, Fernández-Sánchez L, Vidal L, Sánchez-Sáez X, Sánchez-Castillo C, Lax P, Cuenca N, García AG, Maneu V.   +10 more
europepmc   +1 more source

Signal transduction mechanism of P2-purinergic receptors in thyroid cells.

, 1991
Fumikazu Okajima, Hideaki Tomura, Kōichi Sato, Martina Nazarea, Kimie Sho, Yoichi Kondo   +5 more
openalex   +1 more source