Results 171 to 180 of about 35,200 (254)

The Antipsychotic Aripiprazole Induces Cytotoxicity in Bladder Cancer Cells While Preserving Urothelial and Bladder Function

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
Current bladder cancer therapies can cause toxicity and bladder dysfunction. Brief intravesical‐like aripiprazole exposure reduced bladder cancer cell viability and was associated with redox stress and caspase‐3 activation, while ex vivo findings suggested preserved bladder structure and function, warranting further investigation as a potential ...
Liam A. O'Callaghan, Katie Powell, Russ Chess‐Williams, Catherine McDermott   +3 more
wiley   +1 more source

P2Y₂ Nucleotide Receptors Expressed Heterologously in Sympathetic Neurons Inhibit Both N-Type Ca²⁺ and M-Type K⁺ Currents

, 1998
The P2Y₂ receptor is a uridine/adenosine triphosphate (UTP/ATP)-sensitive G-protein-linked nucleotide receptor that previously has been reported to stimulate the phosphoinositide signaling pathway.
Webb, TE, Brown, DA, Barnard, EA, Filippov, AK   +3 more
core  

Ectonucleotidases and purinergic receptors in mouse prostate gland. [PDF]

Am J Clin Exp Urol
Yu J, Sharkey C, Olumi AF, Wang Z.
europepmc   +1 more source

P2X Purinergic Receptors Are Multisensory Detectors for Micro-Environmental Stimuli That Control Migration of Tumoral Endothelium. [PDF]

Cancers (Basel), 2022
Scarpellino G, Genova T, Quarta E, Distasi C, Dionisi M, Fiorio Pla A, Munaron L.   +6 more
europepmc   +1 more source

The Mechanism of NLRP3 Inflammasome Activation and Its Roles in Chronic Rhinosinusitis

World Journal of Otorhinolaryngology - Head and Neck Surgery, Volume 12, Issue 3, Page 362-373, June 2026.
ABSTRACT NLRP3 (NLR family pyrin domain containing 3) is one of the crucial receptors in pathogen recognition receptor (PRR) families which can recognize the pathogen‐associated molecular patterns (PAMPs) and the damage‐associated molecular patterns (DAMPs), thus triggering innate immune response. After NLRP3 activation, it recruits the adaptor protein
Dong‐Lin Li, Yue Li, Yan‐Jie Jiang, Ge‐Hua Zhang, Li‐Hong Chang   +4 more
wiley   +1 more source

Purinergic receptors play a key role in shock wave-induced proliferation. [PDF]

Sci Rep
Szwarc-Hofbauer D, Simböck E, Hromada C, Stoiber M, Tomasch J, Weitzer G, Teuschl-Woller A.   +6 more
europepmc   +1 more source

Expression of purinergic receptors on microglia in the animal model of choroidal neovascularisation. [PDF]

Sci Rep, 2021
Li L, Liu J, Xu A, Heiduschka P, Eter N, Chen C.   +5 more
europepmc   +1 more source

Calcium Buffering in Astrocytes and Its Relevance for Experimental Data Interpretation and Computational Modeling

Journal of Neurochemistry, Volume 170, Issue 6, June 2026.
Components and properties of Ca2+ buffers in astrocytes, which should be considered for data interpretation and in computational modeling of astrocyte Ca2+ activity. ABSTRACT Astrocytic Ca2+ signaling is essential for maintaining physiological brain function, including the modulation of synaptic transmission, neurovascular coupling, and ion homeostasis.
Kerstin Lenk, Andre Zeug, Franziska E. Müller   +2 more
wiley   +1 more source

Global trends of purinergic receptors and depression: A bibliometric analysis from 2003 to 2023. [PDF]

World J Psychiatry
Huang B, Chen WN, Peng CM, Shen XL, Xue J, Yan CC, Zhong FM.   +6 more
europepmc   +1 more source

The role of TRPC6 calcium channels and P2 purinergic receptors in podocyte mechanical and metabolic sensing. [PDF]

Physiol Int, 2022
Gyarmati G, Toma I, Izuhara A, Burford JL, Shroff UN, Papadouri S, Deepak S, Peti-Peterdi J.   +7 more
europepmc   +1 more source