Results 181 to 190 of about 571,618 (248)

Purinergic receptors play a key role in shock wave-induced proliferation. [PDF]

Sci Rep
Szwarc-Hofbauer D, Simböck E, Hromada C, Stoiber M, Tomasch J, Weitzer G, Teuschl-Woller A.   +6 more
europepmc   +1 more source

Expression of purinergic receptors on microglia in the animal model of choroidal neovascularisation. [PDF]

Sci Rep, 2021
Li L, Liu J, Xu A, Heiduschka P, Eter N, Chen C.   +5 more
europepmc   +1 more source

Aberrant alternative splicing of purinergic receptor P2RX4 prevents sensitivity towards combinatorial treatment in colorectal and pancreatic cancer

The Journal of Pathology, Volume 270, Issue 1, Page 55-68, September 2026.
Abstract Recently, we suggested the combination of chemotherapy and P2RX4 inhibition as a promising novel therapeutic approach for P2RX4‐expressing epithelial tumors to prevent paracrine resistance. Here, we aimed to assess whether determining P2RX4 expression status in colorectal and pancreatic cancer patients would allow stratification of potentially
Christoph Steup, Julian Dosch, Christopher Dietz‐Fricke, Sara Khosraviseftejani, Esther Engel, Adalbert F de Valk, Dominic Menger, Patrick Welker, Peter J Wild, Kilian B Kennel, Maja Kantlehner, Paul K Ziegler, Florian R Greten   +12 more
wiley   +1 more source

Global trends of purinergic receptors and depression: A bibliometric analysis from 2003 to 2023. [PDF]

World J Psychiatry
Huang B, Chen WN, Peng CM, Shen XL, Xue J, Yan CC, Zhong FM.   +6 more
europepmc   +1 more source

Piezo1 Activation Rescues Anabolic Response to Mechanical Loading in Aged Bone via Connexin 43 Hemichannels

Aging Cell, Volume 25, Issue 9, September 2026.
Yoda1‐induced Piezo1 activation enhances Piezo1‐Cx43 interaction upon mechanical stimulation, triggering PI3K‐Akt signaling to drive Cx43 phosphorylation and hemichannel opening. These events elevate PGE2 release, suppress SOST expression in senescent osteocytes, and ultimately enhance bone anabolism on the endosteal surface.
Dezhi Zhao, Jiayue Fu, Han Liu, Shuting Liang, Mingming Song, Aining Zhang, Dong‐en Wang, Qianjin Guo, You Zhang, Jiawei Wu, Huiyun Xu   +10 more
wiley   +1 more source

Pannexin-1 channels, extracellular ATP, and purinergic receptors are essential for CCR5/CXCR4 clustering and HIV entry. [PDF]

NeuroImmune Pharm Ther
Ajasin D, Velasquez S, Gibson J, Scemes E, Cibelli A, Spray D, Eugenin EA.   +6 more
europepmc   +1 more source

The role of TRPC6 calcium channels and P2 purinergic receptors in podocyte mechanical and metabolic sensing. [PDF]

Physiol Int, 2022
Gyarmati G, Toma I, Izuhara A, Burford JL, Shroff UN, Papadouri S, Deepak S, Peti-Peterdi J.   +7 more
europepmc   +1 more source

Cannabinoid and adenosine A2A receptor crosstalk regulates postnatal and adult hippocampal neurogenesis

British Journal of Pharmacology, Volume 183, Issue 18, Page 5440-5457, September 2026.
Background and purpose Adult neurogenesis is a tightly regulated process affected by both cannabinoid receptors (CB1 and CB2) and adenosine 2A (A2A) receptors, both of which modulate neural progenitor cell activity. While emerging evidence suggests an interaction between these neuromodulatory systems, the extent and mechanism of their interplay in ...
Rui S. Rodrigues, Adam Armada‐Moreira, Laura Gómez‐Acero, Filipa F. Ribeiro, Francisco M. Mouro, Ana M. Sebastião, Francisco Ciruela, Ester Aso, Sara Xapelli   +8 more
wiley   +1 more source

Platelets, inflammation, and purinergic receptors in chronic kidney disease. [PDF]

Kidney Int
Corken AL, Ong V, Kore R, Ghanta SN, Karaduta O, Pathak R, Rose S, Porter C, Jain N.   +8 more
europepmc   +1 more source

Purinergic receptors of mice podocytes in culture

, 2003
Extrazelluläre Nukleotide wie ATP und UTP sind wichtige Regulatoren glomerulärer Funktionen. In der vorliegenden Arbeit wurde die Reaktion von kultivierten Mauspodozyten auf purinenerge Agonisten mit der Saug-Elektroden Technik und intrazellulärer Ca2 ...
Saueressig, Ulrich
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