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Purinergic signalling in brain ischemia
Neuropharmacology, 2016Ischemia is a multifactorial pathology characterized by different events evolving in the time. After ischemia a primary damage due to the early massive increase of extracellular glutamate is followed by activation of resident immune cells, i.e microglia, and production or activation of inflammation mediators.
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Introduction to Purinergic Signalling in the Brain
2012ATP is a cotransmitter with glutamate, noradrenaline, GABA, acetylcholine and dopamine in the brain. There is a widespread presence of both adenosine (P1) and P2 nucleotide receptors in the brain on both neurons and glial cells. Adenosine receptors play a major role in presynaptic neuromodulation, while P2X ionotropic receptors are involved in fast ...
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Purinergic signaling at immunological synapses
Journal of the Autonomic Nervous System, 2000The early studies and hypotheses of Geoffrey Burnstock catalyzed intensive characterization of roles for nucleotides and P2 nucleotide receptors in neurotransmission and neuromodulation. These latter analyses have focused on the mechanisms of nucleotide release and action in the microenvironments of nerve endings and synapses.
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Purinergic signaling in peripheral nervous system glial cells
Glia, 2021Jennifer Patritti-Cram +2 more
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Possible role of purinergic signaling in COVID-19
Molecular and Cellular Biochemistry, 2021Maria Luiza Mukai Franciosi +2 more
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Purinergic signaling: a potential therapeutic target for ischemic stroke
Purinergic Signalling, 2022Ying-Jie Li +2 more
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Purinergic Signaling in Liver Pathophysiology
Frontiers in Endocrinology, 2021Shanu Jain +2 more
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Astrocyte‐mediated purinergic signaling is upregulated in a mouse model of Fragile X syndrome
Glia, 2021Kathryn Reynolds +2 more
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Purinergic Signaling in Corneal Wound Healing: A Tale of 2 Receptors
Journal of Ocular Pharmacology and Therapeutics, 2016Vickery Trinkaus-Randall
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