Results 291 to 300 of about 4,625,876 (321)
Purinergic signalling in neuron–glia interactions [PDF]
Nature Reviews Neuroscience, 2006 R Douglas Fields, Geoffrey Burnstock
exaly +4 more sources
Purinergic Regulation of Neutrophil Function
Frontiers in Immunology, 2018 Purinergic signaling, which utilizes nucleotides (particularly ATP) and adenosine as transmitter molecules, plays an essential role in immune system. In the extracellular compartment, ATP predominantly functions as a pro-inflammatory molecule through ...
Xu Wang
exaly +3 more sources
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Astrocyte‐mediated purinergic signaling is upregulated in a mouse model of Fragile X syndrome
Glia, 2021Fragile X syndrome (FXS) is the leading monogenic cause of intellectual disability and autism spectrum disorders. With increasing investigation into the molecular mechanisms underlying FXS, there is growing evidence that perturbations in glial signaling ...
Angela L Scott, Kathryn E Reynolds
exaly +2 more sources
Purinergic Signalling in the Cerebellum [PDF]
, 2013 Purinergic signalling is a complex and evolutionarily conserved mechanism of extracellular communication involved in many physiological and pathological functions. The complexity arises from a large number of purine receptor subtypes and multiple endogenous purine receptor ligands (including ATP, ADP, UTP, UDP UDP-glucose and adenosine) which can be ...
Boris P. Klyuch, Mark J. Wall
openaire +2 more sources
Purinergic Signaling in the Airways
Pharmacological Reviews, 2012Evidence for a significant role and impact of purinergic signaling in normal and diseased airways is now beyond dispute. The present review intends to provide the current state of knowledge of the involvement of purinergic pathways in the upper and lower airways and lungs, thereby differentiating the involvement of different tissues, such as the ...
Burnstock, Geoffrey +3 more
openaire +4 more sources
Purinergic signaling in atherosclerosis
Trends in Molecular Medicine, 2015Cell surface expression of specific receptors and ecto-nucleotidases makes extracellular nucleotides such as ATP, ADP, UTP, and adenosine suitable as signaling molecules for physiological and pathological events, including tissue stress and damage.
FERRARI, Davide +3 more
openaire +5 more sources
Purinergic signaling and microglia
Pflügers Archiv - European Journal of Physiology, 2006Microglial cells are considered as the pathologic sensors of the brain. In this paper, we review mechanisms of purinergic signaling in microglia. As ATP is not only considered as a physiological signaling substance but is also elevated in pathology, it is not surprising that microglia express a variety of P2X, P2Y and adenosin receptors.
Katrin Färber, Helmut Kettenmann
openaire +2 more sources
Brain Research Reviews, 2010
A growing body of evidence indicates that extracellular nucleotides play important roles in the regulation of neuronal and glial functions in the nervous system through P2 purinoceptors. P2 purinoceptors are divided into two families, ionotropic receptors (P2X) and metabotropic receptors (P2Y).
Makoto Tsuda +2 more
openaire +3 more sources
A growing body of evidence indicates that extracellular nucleotides play important roles in the regulation of neuronal and glial functions in the nervous system through P2 purinoceptors. P2 purinoceptors are divided into two families, ionotropic receptors (P2X) and metabotropic receptors (P2Y).
Makoto Tsuda +2 more
openaire +3 more sources
Glycogenolysis and Purinergic Signaling
2014Both ATP and glutamate are on one hand essential metabolites in brain and on the other serve a signaling function as transmitters. However, there is the major difference that the flux in the pathway producing transmitter glutamate is comparable to the rate of glucose metabolism in brain, whereas that producing transmitter ATP is orders of magnitude ...
Junnan Xu, Leif Hertz, Liang Peng
openaire +3 more sources
Purinergic Signalling and Endothelium
Current Vascular Pharmacology, 2016Purinergic signalling is involved in the control of vascular tone and remodelling. Endothelial cells release purines and pyrimidines in response to changes in blood flow (evoking shear stress) and hypoxia. They then act on P2Y, P2X and P1 receptors on endothelial cells leading to release of EDRF mediated by nitric oxide and prostaglandins and EDHF ...
openaire +3 more sources