Results 1 to 10 of about 59,115 (293)
Regioselective synthesis of triazolo[3,4-e]purine derivatives and their anti-cancer activity against NCI-60 cell-lines [PDF]
Folia Medica, 2021 Introduction: Due to the vast medicinal importance of purine nucleoside, a hybrid molecule of triazole with purine ring might explode a lead molecule in the pharma sector and based on the last decade’s studies suggested that the ...
Khushal Kapadiya +3 more
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Infrared Spectral Signatures of Nucleobases in Interstellar Ices I: Purines
Life, 2023 The purine nucleobases adenine and guanine are complex organic molecules that are essential for life. Despite their ubiquitous presence on Earth, purines have yet to be detected in observations of astronomical environments.
Caroline Antunes Rosa +11 more
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Protonated pyrimidine-purine-purine triplex [PDF]
Nucleic Acids Research, 1993 We have studied a protonated pyrimidine-purine-purine (Py-Pu-Pu) triplex, which is formed between the d(C)nd(G)n duplex and the d(AG)m oligonucleotide as the third strand and carries the CG*A+ protonated base-triads. We have observed such an intermolecular complex between a plasmid carrying the d(C)18 d(G)18 insert and the d(AG)5 oligonucleotide ...
Ingeborg Jansen +7 more
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The interaction of aflatoxins with purines and purine nucleosides [PDF]
Biochemical Journal, 1967 From measurements of thermal hyperchromicity and the behaviour of an aflatoxin-DNA mixture on a Sephadex column it was concluded that aflatoxin B(1) is capable of weak binding to single-stranded DNA. The interactions of the aflatoxins (B(1), G(1) and G(2)) with nucleosides result in difference spectra and suggest that the purine bases and the amino ...
K. R. Rees, Janet I. Clifford
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Frontiers in Physiology, 2021 To our knowledge, this is the first study in which we provide evidence that a single whole-body cryostimulation treatment leads to changes associated with erythrocyte energy metabolism.
Wioleta Dudzinska +2 more
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Structure–activity features of purines and their receptors: implications in cell physiopathology
Molecular Biomedicine, 2022 The purine molecular structure consists of fused pyrimidine and imidazole rings. Purines are main pieces that conform the structure of nucleic acids which rule the inheritance processes.
Mauricio Díaz-Muñoz +2 more
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Molecules, 2022 In the context of our SAR study concerning 6BrCaQ analogues as C-terminal Hsp90 inhibitors, we designed and synthesized a novel series of 3-(heteroaryl)quinolin-2(1H), of types 3, 4, and 5, as a novel class of analogues.
Enrique L. Larghi +5 more
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Purine Auxotrophic Starvation Evokes Phenotype Similar to Stationary Phase Cells in Budding Yeast
Journal of Fungi, 2021 Purine auxotrophy is an abundant trait among eukaryotic parasites and a typical marker for many budding yeast strains. Supplementation with an additional purine source (such as adenine) is necessary to cultivate these strains. If not supplied in adequate
Agnese Kokina +6 more
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Ciencia y Tecnología Agropecuaria, 2023 Existen pruebas estandarizadas para evaluar la calidad de las semillas y para ensayos de biomonitoreo ambiental, las cuales utilizan indicadores que permiten establecer la sensibilidad de diversas especies a condiciones ambientales, aunque los momentos ...
Lorna Ileana Carbó +4 more
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