Results 1 to 10 of about 110,633 (375)
Microorganisms, 2017 Excessive intake of purine-rich foods elevates serum levels of uric acid. Animal and fish meats contain high amounts of inosine and its related purines, and the reduction of taking those purines is crucial for the improvement of serum uric acid levels ...
Richard Hr Hahnloser, J Duarte
exaly +2 more sources
Evolutionary convergence in the biosyntheses of the imidazole moieties of histidine and purines
PLoS ONE, 2018 Background The imidazole group is an ubiquitous chemical motif present in several key types of biomolecules. It is a structural moiety of purines, and plays a central role in biological catalysis as part of the side-chain of histidine, the amino acid ...
Alberto Vázquez-salazar +2 more
exaly +2 more sources
From purines to purinergic signalling: molecular functions and human diseases
Signal Transduction and Targeted Therapy, 2021 Alexei Verkhratsky +2 more
exaly +2 more sources
Substrate identification of putative NCS1 and NCS2 nucleobase transporters in <i>Pseudomonas aeruginosa</i>. [PDF]
mBioPseudomonas aeruginosa is an opportunistic pathogen that can salvage nucleobases from the environment to conserve nutrients that would otherwise be spent on de novo nucleotide biosynthesis.
Kennelly C, Prindle A.
europepmc +2 more sources
Role of purines in regulation of metabolic reprogramming
Purinergic Signalling, 2019 Cong Peng, Hong Liu, Jia Guo
exaly +2 more sources
Infrared Spectral Signatures of Nucleobases in Interstellar Ices I: Purines
Life, 2023 The purine nucleobases adenine and guanine are complex organic molecules that are essential for life. Despite their ubiquitous presence on Earth, purines have yet to be detected in observations of astronomical environments.
Caroline Antunes Rosa +11 more
doaj +1 more source
Regioselective synthesis of triazolo[3,4-e]purine derivatives and their anti-cancer activity against NCI-60 cell-lines [PDF]
Folia Medica, 2021 Introduction: Due to the vast medicinal importance of purine nucleoside, a hybrid molecule of triazole with purine ring might explode a lead molecule in the pharma sector and based on the last decade’s studies suggested that the ...
Khushal Kapadiya +3 more
doaj +3 more sources
Protonated pyrimidine-purine-purine triplex [PDF]
Nucleic Acids Research, 1993 We have studied a protonated pyrimidine-purine-purine (Py-Pu-Pu) triplex, which is formed between the d(C)nd(G)n duplex and the d(AG)m oligonucleotide as the third strand and carries the CG*A+ protonated base-triads. We have observed such an intermolecular complex between a plasmid carrying the d(C)18 d(G)18 insert and the d(AG)5 oligonucleotide ...
Ingeborg Jansen +7 more
openaire +3 more sources
Novel Point-of-Care Diagnostic Method for Neonatal Encephalopathy Using Purine Nucleosides
Frontiers in Molecular Neuroscience, 2021 Background: Evidence suggests that earlier diagnosis and initiation of treatment immediately after birth is critical for improved neurodevelopmental outcomes following neonatal encephalopathy (NE). Current diagnostic tests are, however, mainly restricted
Edward Beamer +31 more
doaj +1 more source