Protonated pyrimidine-purine-purine triplex [PDF]
Nucleic Acids Research, 1993 We have studied a protonated pyrimidine-purine-purine (Py-Pu-Pu) triplex, which is formed between the d(C)nd(G)n duplex and the d(AG)m oligonucleotide as the third strand and carries the CG*A+ protonated base-triads. We have observed such an intermolecular complex between a plasmid carrying the d(C)18 d(G)18 insert and the d(AG)5 oligonucleotide ...
V A, Malkov +6 more
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The interaction of aflatoxins with purines and purine nucleosides [PDF]
Biochemical Journal, 1967 From measurements of thermal hyperchromicity and the behaviour of an aflatoxin-DNA mixture on a Sephadex column it was concluded that aflatoxin B(1) is capable of weak binding to single-stranded DNA. The interactions of the aflatoxins (B(1), G(1) and G(2)) with nucleosides result in difference spectra and suggest that the purine bases and the amino ...
J I, Clifford, K R, Rees
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Ischemic preconditioning attenuates portal venous plasma concentrations of purines following warm liver ischemia in man [PDF]
, 2005 Background/Aims: Degradation of adenine nucleotides to adenosine has been suggested to play a critical role in ischemic preconditioning (IPC). Thus, we questioned in patients undergoing partial hepatectomy whether (i) IPC will increase plasma purine ...
Chouker, A. +9 more
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A New Class of Nucleosides. Synthesis, Reactivity and Biological Activity of Keto-Hexose Nucleosides
CHIMIA, 1975 Direct oxydation of sterically hindered hexosyl purines led to keto-hexosylpurines, important synthetic intermediates. The first unsaturated keto-nucleosides have also been obtained by acetylation of the corresponding keto-hexosyl purines.
K. Antonakis
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Hoogsteen base pairs proximal and distal to echinomycin binding sites on DNA [PDF]
, 1987 Forms of the DNA double helix containing non-Watson-Crick base-pairing have been discovered recently based on x-ray diffraction analysis of quinoxaline antibiotic-oligonucleotide complexes.
Dervan, Peter B., Mendel, David
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The exercise sex gap and the impact of the estrous cycle on exercise performance in mice
Scientific Reports, 2018 Exercise physiology is different in males and females. Females are poorly studied due to the complexity of the estrous cycle and this bias has created an exercise sex gap.
Aderbal S. Aguiar +4 more
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Purinergic Signalling in Inflammatory Renal Disease
Frontiers in Physiology, 2013 Extracellular purines have a role in renal physiology and adaption to inflammation. However, inflammatory renal disease may be mediated by extracellular purines, resulting in renal injury.
Nishkantha eArulkumaran +6 more
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Scientific investigations of the Nobel prize winner Emil Fischer as a launching pad for the development of biochemistry: a brief overview [PDF]
The Ukrainian Biochemical Journal, 2018 Modern biochemistry and molecular biology would be impossible without discoveries in related fields of science. This paper aims to outline briefly the main stages of scientific activity of a Nobel Prize winner 1902 – German chemist Hermann Emil Fischer ...
T. V. Danylova, S. V. Komisarenko
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Transiently Transfected Purine Biosynthetic Enzymes Form Stress Bodies [PDF]
, 2013 It has been hypothesized that components of enzymatic pathways might organize into intracellular assemblies to improve their catalytic efficiency or lead to coordinate regulation.
Cook, Lindsey +5 more
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, 2008 INTRODUCTION: Gout affects about 5% of men and 1% of women, with up to 80% of people experiencing a recurrent attack within 3 years. METHODS AND OUTCOMES:We conducted a systematic review and aimed to answer the following clinical questions: What are the
Underwood, Martin
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