Results 11 to 20 of about 53,976 (309)

Changes in the Concentration of Purine and Pyridine as a Response to Single Whole-Body Cryostimulation

open access: yesFrontiers in Physiology, 2021
To our knowledge, this is the first study in which we provide evidence that a single whole-body cryostimulation treatment leads to changes associated with erythrocyte energy metabolism.
Wioleta Dudzinska   +2 more
doaj   +1 more source

The exercise sex gap and the impact of the estrous cycle on exercise performance in mice

open access: yesScientific Reports, 2018
Exercise physiology is different in males and females. Females are poorly studied due to the complexity of the estrous cycle and this bias has created an exercise sex gap.
Aderbal S. Aguiar   +4 more
doaj   +1 more source

Cardiovascular Pharmacology of Purines [PDF]

open access: yesClinical Science, 1997
1. This review focuses on the extracellular actions of ATP and adenosine, and in particular their role in cardiovascular regulation. 2. ATP serves as a co-transmitter within the sympathetic nervous system, and is also released from endothelium and aggregating thrombocytes.
Rongen, G.A.P.J.M.   +4 more
openaire   +4 more sources

2,6-Bis[4-(4-butylphenyl)-1H-1,2,3-triazol-1-yl]-9-dodecyl-9H-purine

open access: yesMolbank, 2019
Target 2,6-bis[4-(4-butylphenyl)-1H-1,2,3-triazol-1-yl]-9-dodecyl-9H-purine has been prepared via a Cu(I)-catalyzed azide-alkyne 1,3-dipolar cycloaddition reaction between 2,6-diazido-9-dodecyl-9H-purine and 4-n-butyl(phenylacetylene) in a 29% yield. The
Andrejs Šišuļins   +3 more
doaj   +1 more source

Deoxyribonucleotide Triphosphate Metabolism in Cancer and Metabolic Disease

open access: yesFrontiers in Endocrinology, 2018
The maintenance of a healthy deoxyribonucleotide triphosphate (dNTP) pool is critical for the proper replication and repair of both nuclear and mitochondrial DNA.
Raquel Buj, Katherine M. Aird
doaj   +1 more source

RNA Catabolites Contribute to the Nitrogen Pool and Support Growth Recovery of Wheat

open access: yesFrontiers in Plant Science, 2018
Turn-over of RNA and catabolism of nucleotides releases one to four ammonia molecules; the released nutrients being reassimilated into primary metabolism.
Vanessa Jane Melino   +8 more
doaj   +1 more source

Genetic Screen Reveals the Role of Purine Metabolism in Staphylococcus aureus Persistence to Rifampicin

open access: yesAntibiotics, 2015
Chronic infections with Staphylococcus aureus such as septicemia, osteomyelitis, endocarditis, and biofilm infections are difficult to treat because of persisters.
Rebecca Yee   +4 more
doaj   +1 more source

Meat quality of rabbits reared with two different feeding strategies: with or without fresh alfalfa ad libitum

open access: yesWorld Rabbit Science, 2013
The aim of this study was to evaluate production performance, carcass characteristics and nutritive value of meat of rabbits reared under the 2 prevailing feeding strategies in Uruguay.
Gustavo Capra   +6 more
doaj   +1 more source

Purine Auxotrophic Starvation Evokes Phenotype Similar to Stationary Phase Cells in Budding Yeast

open access: yesJournal of Fungi, 2021
Purine auxotrophy is an abundant trait among eukaryotic parasites and a typical marker for many budding yeast strains. Supplementation with an additional purine source (such as adenine) is necessary to cultivate these strains. If not supplied in adequate
Agnese Kokina   +6 more
doaj   +1 more source

Synthesis and Biological Activity of 3-(Heteroaryl)quinolin-2(1H)-ones Bis-Heterocycles as Potential Inhibitors of the Protein Folding Machinery Hsp90

open access: yesMolecules, 2022
In the context of our SAR study concerning 6BrCaQ analogues as C-terminal Hsp90 inhibitors, we designed and synthesized a novel series of 3-(heteroaryl)quinolin-2(1H), of types 3, 4, and 5, as a novel class of analogues.
Enrique L. Larghi   +5 more
doaj   +1 more source

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