Results 241 to 250 of about 98,235 (335)

Plant organelle C‐to‐U RNA editing factors can operate successfully in yeast (Saccharomyces cerevisiae) as an easily amenable eukaryotic system for their functional analysis

The FEBS Journal, EarlyView.
Plant‐type pentatricopeptide repeat proteins capable of C‐to‐U RNA editing perform faithfully when expressed in a new heterologous system, the yeast Saccharomyces cerevisiae. They were tested with constitutive and inducible expression and with a set of different solubility tags. PPR56, PPR65, and PPR78 from P.
Shyam Ramanathan, Annika Hanraths, Jingchan Xie, Mareike Schallenberg‐Rüdinger, Volker Knoop   +4 more
wiley   +1 more source

From molecule to medicine: introducing emerging strategies to synthesize potent anticancer purine scaffolds. [PDF]

RSC Adv
Hashmi MA, Kanwal A, Siddiqua UH, Rasool N, Malik A.   +4 more
europepmc   +1 more source

Hypoxia modulates the purine salvage pathway and decreases red blood cell and supernatant levels of hypoxanthine during refrigerated storage [PDF]

, 2018
Doctor, Allan, et al.,, Rogers, Stephen C   +2 more
core   +1 more source

Ultrastructural expansion microscopy reveals unexpected levels of glycosome heterogeneity in African trypanosomes

Journal of Microscopy, EarlyView.
Abstract Kinetoplastid parasites include several species. Trypanosoma brucei causes African sleeping sickness in humans and a wasting disease nagana in livestock. Trypanosoma cruzi is the causative agent of Chagas disease and Leishmania species cause leishmaniasis, which can present with visceral, cutaneous, or mucocutaneous symptoms.
Heidi Anderson, Rhonda Reigers Powell, Meredith Teilhet Morris   +2 more
wiley   +1 more source

Uridine-sensitized screening identifies demethoxy-coenzyme Q and NUDT5 as regulators of nucleotide synthesis. [PDF]

Nat Metab
Strefeler A, Baker ZN, Chollet S, Foged MM, Guerra RM, Ivanisevic J, Gallart-Ayala H, Pagliarini DJ, Jourdain AA.   +8 more
europepmc   +1 more source

Increasing Rumen Microbial Diversity in Goats Favours the Adaptation to High‐Concentrate Diets With Minor Effects on Feed Utilization

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Evolution has enabled ruminants to develop a complex rumen microbiota that aids in the digestion of fibrous feeds. This study examines whether promoting a highly diverse rumen microbiota during early life continues to offer long‐term benefits in modern dairy production systems, where young ruminants are reared without exposure to adult ...
Alejandro Belanche, Juan Manuel Palma‐Hidalgo, David R. Yáñez‐Ruiz   +2 more
wiley   +1 more source

Purine Chemistry in the Early RNA World at the Origins of Life: From RNA and Nucleobases Lesions to Current Key Metabolic Routes. [PDF]

Chembiochem
Décout JL, Maurel MC.
europepmc   +1 more source

A new folate antimetabolite, 5,10-dideaza-5,6,7,8-tetrahydrofolate is a potent inhibitor of de novo purine synthesis

, 1989
G. Peter Beardsley, Barbara A. Moroson, Edward C. Taylor, R G Moran   +3 more
openalex   +1 more source

When chemistry meets taxonomy: Studying glycolipidic chemomarkers in pelagic Sargassum spp. (Phaeophyceae) using molecular networking

Journal of Phycology, EarlyView.
Abstract To chemically differentiate the three pelagic Sargassum morphotypes co‐occurring in floating rafts and drifting across the Atlantic Ocean before stranding on West African, Caribbean, and Atlantic Mexican coastlines, we conducted an investigation of their metabolomic profiles.
Charlotte Nirma, Valérie Stiger‐Pouvreau, Marceau Levasseur, David Touboul, Solène Connan, Sylvain Petek   +5 more
wiley   +1 more source

<i>Listeria monocytogenes</i> adenosine auxotrophs are impaired for intracellular and extracellular growth but retain potent immunogenicity. [PDF]

Infect Immun
Feng Y, Lobanovska M, Vickery J, Castillo JG, Güereca L, Chang SK, DuPage M, Portnoy DA.   +7 more
europepmc   +1 more source