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Biosynthesis of the purines

Journal of Cellular and Comparative Physiology, 1951
GAR transformylase, which is responsible for the incorporation of formate carbon into what becomes position 8 of the purine ring, has been completely separated from 5-amino-4-imidazolecarboxamide ribotide transformylase (3). The latter enzyme is responsible for the incorporation of formate carbon into position 2 of the purine ring.
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Analysis of purines

Life Sciences, 1987
The fact that purine nucleotides and nucleosides are so important in normal cellular functions makes their analysis complicated. In order to measure tissue levels, samples have to be very rapidly fixed. Measurement in blood is complicated by the risk of releasing purine nucleotides during the sampling procedure and by the possibility of very rapid ...
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Inhibition of Lipid Peroxidation by Purines and Analogues of Purine

1995
The importance of oxygen radicals in tissue injury is widely recognized(1). Mutation, cancer, inflammation, and ageing are thought to be caused by oxygen radicals. It has also been confirmed that lipids are peroxidized by oxygen radicals leading to the damaging effects on cellular constituents. Mickel & Horbar(2) reported that peroxidized lipids affect
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Purines in Portugal

Trends in Neurosciences, 2001
T W, Stone   +3 more
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Purines '96

Trends in Pharmacological Sciences, 1996
S P, Alexander, A P, Ford
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Purine Sulfonamides

Journal of Medicinal Chemistry, 1966
A G, Beaman   +3 more
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The influence of dietary purines and pyrimidines on purine.

Infusionstherapie und klinische Ernahrung, 1977
Allopurinol-induced orotaciduria is reduced by dietary ribonucleic acid (RNA), RNA hydrolysate and different nucleotides. These findings are compatible with feedback regulation of pyrimidine biosynthesis by dietary nucleotides. Serum uric acid and urinary uric acid excretion on a purine-free isoenergetic diet reach a minimum after about 10 days and ...
W, Gröbner, N, Zöllner
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