Results 81 to 90 of about 98,235 (335)

Synthesis of Purine-1,4,7,10-Tetraazacyclododecane Conjugate and Its Complexation Modes with Copper(II)

Molecules
Purine-1,4,7,10-tetraazacyclododecane (cyclen) conjugate was designed to study its Cu2+ ions complexation capability. Several synthetic approaches were tested to achieve the target compound.
Aleksejs Burcevs, Gediminas Jonusauskas, Irina Novosjolova, Māris Turks   +3 more
doaj   +1 more source

RNA Catabolites Contribute to the Nitrogen Pool and Support Growth Recovery of Wheat

Frontiers in Plant Science, 2018
Turn-over of RNA and catabolism of nucleotides releases one to four ammonia molecules; the released nutrients being reassimilated into primary metabolism.
Vanessa Jane Melino, Vanessa Jane Melino, Alberto Casartelli, Jessey George, Thusitha Rupasinghe, Ute Roessner, Mamoru Okamoto, Sigrid Heuer, Sigrid Heuer   +8 more
doaj   +1 more source

Nucleoprotein content of "L" strain of Staphylococcus aureus [PDF]

, 1950
Thesis (M.A.)--Boston ...
Fish, Charles Austin
core   +1 more source

Overcoming EGFR‐Mediated Dendritic Cell Dysfunction to Enhance Anti‐tumor Immunity in EGFR‐Mutant NSCLC by Precisely Targeting CD73 With pH‐responsive Nanocarriers

Advanced Science, EarlyView.
EGFR mutations drive ERK/c‐Jun–mediated transcriptional activation of CD73, elevating adenosine levels and fostering an immunosuppressive TME by impairing DC maturation and CD8⁺ T cell priming. The pH‐responsive nanodrug F127ZIF‐8AB680 selectively inhibits CD73, normalizes adenosine metabolism, and re‐establishes effective anti‐tumor immunity ...
Xiaoling Shang, Xudong Geng, Zixu Wang, Shumin Yuan, Shanshan Ding, Ni Liu, Xinchun Ma, Xuan Sun, Huimin Wang, Ying Sun, Xun Qu, Guangwen Ren, Yong Qiang Li, Xiuwen Wang, Yanguo Liu   +14 more
wiley   +1 more source

Effectiveness of Multivitamins vs Folic Acid on Prevention of Neural Tube Defects in Mouse Genetic Models and Human Organoids

Advanced Science, EarlyView.
Folic acid (FA) and multivitamins/minerals (MVM) are recommended for the prevention of neural tube defects (NTDs). Using a novel human neural tube‐like organoid system and mouse models, the study compares the effectiveness of two supplements on NTDs and cellular behaviors.
Huili Li, Jing Zhang, Lori Bulwith, Lee Niswander   +3 more
wiley   +1 more source

Assessment of purine catabolism and morbidity in miners depending on their work experience

Russian Open Medical Journal
Objective — The role of end products of purine metabolism as predictors of the development of pathological changes and diseases caused by the impact of dust on the human body in a professional environment vs.
Diana M. Shaukhat, Lyazat K. Ibrayeva, Dina Kh. Rybalkina, Irina V. Bacheva, Igor V. Bukhtiyarov, Aigul U. Amanbekova, Tleуuzhan O. Abugalieva   +6 more
doaj   +1 more source

Atomic mutagenesis of stop codon nucleotides reveals the chemical prerequisites for release factor-mediated peptide release. [PDF]

, 2018
Termination of protein synthesis is triggered by the recognition of a stop codon at the ribosomal A site and is mediated by class I release factors (RFs).
Clementi, Nina, Erlacher, Matthias David, Faserl, Klaus, Gasser, Catherina, Hoernes, Thomas Philipp, Hüttenhofer, Alexander, Joseph, Simpson, Juen, Michael Andreas, Kreutz, Christoph, Lindner, Herbert, Shi, Xinying, Willi, Jessica   +11 more
core   +3 more sources

Microdroplet Stabilization Enabled Direct Mass Spectrometric Identification of Electrogenerated Transient Carbocation Intermediates

Advanced Science, EarlyView.
The in situ mass spectrometric identification of the electrogenerated benzylic and phenylic carbocations, whose half‐lives in bulk solutions are on the nanosecond scale, is achieved by taking advantage of the unique stabilization effect of the electrosprayed microdroplets.
Guo‐Shan Zhu, Ren‐Jie Hui, Jun Hu
wiley   +1 more source

Synthesis of Adenine Nucleosides with a Reactive (β-Iodovinyl)sulfone or (β-Keto)sulfone Group at the C2 Position and Their Polymerase-Catalyzed Incorporation into DNA

Molecules
Iodosulfonylation of an ethynyl group at the C2 position of 2′-deoxyadenosine or adenosine with TsI provides (E)-2-(β-iodovinyl)sulfones. The latter undergo nucleophilic substitution with amines via an addition–elimination to give β-sulfonylvinylamines ...
A. Hasan Howlader, Richard Fernandez, Pawlos S. Tsegay, Yuan Liu, Stanislaw F. Wnuk   +4 more
doaj   +1 more source

Chemical markers for rumen methanogens and methanogenesis [PDF]

, 2013
Peer reviewedPublisher ...
Bessa, Bhagwat, Brulc, C.A. McCartney, Casto Montoya, Chen, Chilliard, Dehareng, Dehority, Dewhurst, Dewhurst, Diedrich, Dijkstra, Ding, Fievez, Firkins, Frey, Fritze, Gill, Gill, Gu, Guo, Hegarty, Hildenbrand, Hook, Hopmans, Huguet, I.D. Bull, Janssen, Jenkins, Kim, Koga, Koga, Lee, Leng, Liu, Mao, Mathai, McCartney, McGeough, Mohammed, Morgavi, Mosoni, Odongo, Pancost, Pei, Pinares-Patiño, Polidori, R.J. Dewhurst, Schouten, Schouten, Sharp, Shimada, Shin, Shingfield, Stouthamer, Thauer, Tymensen, Valentine, Vlaeminck, Vlaeminck, Weijers, Zhou, Zhou   +63 more
core   +1 more source