The sodium-potassium pump controls the intrinsic firing of the cerebellar Purkinje neuron [PDF]
PLoS ONE, 2012 In vitro, cerebellar Purkinje cells can intrinsically fire action potentials in a repeating trimodal or bimodal pattern. The trimodal pattern consists of tonic spiking, bursting, and quiescence.
Feng, Jianfeng +3 more
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Serotonin drives a novel GABAergic synaptic current recorded in rat cerebellar purkinje cells: a lugaro cell to Purkinje cell synapse [PDF]
, 2003 We recorded a novel fast GABAergic synaptic current in cerebellar Purkinje cells in rat brain slices using patch-clamp techniques. Because of a relatively low sensitivity to bicuculline, these currents can be recorded under conditions in which basket ...
Dean, I., Edwards, F.A., Robertson, S.J.
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The Cerebellum and SIDS: Disordered Breathing in a Mouse Model of Developmental Cerebellar Purkinje Cell Loss during Recovery from Hypercarbia. [PDF]
, 2016 The cerebellum assists coordination of somatomotor, respiratory, and autonomic actions. Purkinje cell alterations or loss appear in sudden infant death and sudden death in epilepsy victims, possibly contributing to the fatal event. We evaluated breathing
Calton, Michele A +4 more
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Spiral-wave dynamics in a mathematical model of human ventricular tissue with myocytes and Purkinje fibers [PDF]
, 2017 We present systematic numerical studies of the possible effects of the coupling of human endocardial and Purkinje cells at cellular and two-dimensional tissue levels.
Nayak, Alok Ranjan +2 more
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Cerebellar Cortex, Purkinje Cell Layer [PDF]
, 2008 This report contains a summary of expression patterns for genes that are enriched in the Purkinje cell layer (CBXpu) of the cerebellum. All data is derived from the Allen Brain Atlas (ABA) in situ hybridization mouse project.
Allen Institute for Brain Science +3 more
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Purkinje cell injury, structural plasticity and fusion in patients with Friedreich's ataxia [PDF]
, 2016 Purkinje cell pathology is a common finding in a range of inherited and acquired cerebellar disorders, with the degree of Purkinje cell injury dependent on the underlying aetiology.
Cook, Amelia +5 more
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Lack of NMDA receptor subunit exchange alters Purkinje cell dendritic morphology in cerebellar slice cultures [PDF]
, 2005 Early postnatal developmental changes in N-methyl-D-aspartate (NMDA) receptor (NR) subunits regulate cerebellar granule cell maturation and potentially Purkinje cell development.
Eisel, ULM +3 more
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Olig2/Plp-positive progenitor cells give rise to Bergmann glia in the cerebellum. [PDF]
, 2013 NG2 (nerve/glial antigen2)-expressing cells represent the largest population of postnatal progenitors in the central nervous system and have been classified as oligodendroglial progenitor cells, but the fate and function of these cells remain ...
Chung, S-H +4 more
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Purkinje cell-specific Grip1/2 knockout mice show increased repetitive self-grooming and enhanced mGluR5 signaling in cerebellum [PDF]
, 2019 Cerebellar Purkinje cell (PC) loss is a consistent pathological finding in autism. However, neural mechanisms of PC-dysfunction in autism remain poorly characterized.
Chiu, Shu-Ling +6 more
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Reduced Purkinje cell number in essential tremor : a postmortem study [PDF]
, 2008 Background: Clinical and functional imaging evidence suggests that cerebellar dysfunction occurs in essential tremor (ET). In recent postmortem studies, we documented increased numbers of torpedoes (Purkinje cell axonal swellings) in ET patients without ...
Axelrad, Jordan E. +8 more
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