β-III spectrin underpins ankyrin R function in Purkinje cell dendritic trees:Protein complex critical for sodium channel activity is impaired by SCA5-associated mutations [PDF]
, 2014 Beta III spectrin is present throughout the elaborate dendritic tree of cerebellar Purkinje cells and is required for normal neuronal morphology and cell survival.
Perkins, Emma M. +6 more
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Purkinje Cell Conditioned Pause Parameters
, 2021 Trial-by-trial analysis of the conditional pause in the spontaneous firing of the Purkinje cell; data from Hesslow ...
Charles Randy Gallistel
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Developmental Regulation of Small-Conductance Ca²⁺-Activated K⁺ Channel Expression and Function in Rat Purkinje Neurons [PDF]
, 2002 Calcium transients play an important role in the early and later phases of differentiation and maturation of single neurons and neuronal networks. Small-conductance calcium-activated potassium channels of the SK type modulate membrane excitability and ...
Stocker, M +19 more
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Establishment of topographic circuit zones in the cerebellum of scrambler mutant mice
Frontiers in Neural Circuits, 2013 The cerebellum is organized into zonal circuits that are thought to regulate ongoing motor behavior. Recent studies suggest that neuronal birthdates, gene expression patterning, and apoptosis control zone formation.
Stacey L Reeber +3 more
doaj +1 more source
Mechanisms and consequences of reduced dendritic growth of cerebellar Purkinje cells [PDF]
, 2012 The cerebellum is a brain region crucial for coordination and motor learning. Being the principal output cell of the cerebellar cortex, Purkinje cell loss and degeneration play an important role in many cerebellar diseases.
Gugger, Olivia S.
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mTORC2 controls neuron size and Purkinje cell morphology independent of mTORC1 [PDF]
, 2012 Prenatal brain development is mainly accomplished by extensive proliferation of neuronal precursor cells whereas postnatal brain growth in mammals is mainly mediated by the growth of those post-mitotic nerve cells.
Thomanetz, Venus
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Frontiers in Aging Neuroscience, 2023 Dietary restriction (DR) is a universal anti-aging intervention, which reduces age-related nervous system pathologies and neurological decline. The degree to which the neuroprotective effect of DR operates by attenuating cell intrinsic degradative ...
María Björk Birkisdóttir +12 more
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Distinct and common functions of mTORC1 and mTORC2 in Purkinje cells [PDF]
, 2015 In mammalian cells, the serine/threonine protein kinase mTOR (mammalian target of rapamycin) is present in two complexes, called mTORC1 and mTORC2. While several of the components are common to both complexes, raptor and rictor are only associated with ...
Angliker, Nico
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Purkinje cell responses during diverse Granule cell plasticity scenarios
, 2022 Purkinje cell responses during diverse Granule cell plasticity ...
Robin De Schepper
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Fear conditioning-related changes in cerebellar Purkinje cell activities in goldfish
Behavioral and Brain Functions, 2012 Background Fear conditioning-induced changes in cerebellar Purkinje cell responses to a conditioned stimulus have been reported in rabbits. It has been suggested that synaptic long-term potentiation and the resulting increases in firing rates of Purkinje
Yoshida Masayuki, Kondo Hiroki
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