Results 11 to 20 of about 48,590 (271)

Microcircuit Rules Governing Impact of Single Interneurons on Purkinje Cell Output In Vivo [PDF]

open access: yesCell Reports, 2020
Summary: The functional impact of single interneurons on neuronal output in vivo and how interneurons are recruited by physiological activity patterns remain poorly understood.
Charlotte Arlt, Michael Häusser
doaj   +2 more sources

The sodium-potassium pump controls the intrinsic firing of the cerebellar Purkinje neuron. [PDF]

open access: yesPLoS ONE, 2012
In vitro, cerebellar Purkinje cells can intrinsically fire action potentials in a repeating trimodal or bimodal pattern. The trimodal pattern consists of tonic spiking, bursting, and quiescence.
Michael D Forrest   +3 more
doaj   +4 more sources

Remodeling of monoplanar Purkinje cell dendrites during cerebellar circuit formation. [PDF]

open access: yesPLoS ONE, 2011
Dendrite arborization patterns are critical determinants of neuronal connectivity and integration. Planar and highly branched dendrites of the cerebellar Purkinje cell receive specific topographical projections from two major afferent pathways; a single ...
Megumi Kaneko   +9 more
doaj   +3 more sources

Purkinje cell stripes and long-term depression at the parallel fiber-Purkinje cell synapse [PDF]

open access: yesFrontiers in Systems Neuroscience, 2014
Article deposited according to Frontiers policy for Frontiers in Systems Neuroscience: http://www.frontiersin.org/about/faq June 18 ...
Richard eHawkes, Richard Hawkes
openaire   +6 more sources

Purkinje cell neurotransmission patterns cerebellar basket cells into zonal modules defined by distinct pinceau sizes

open access: yeseLife, 2020
Ramón y Cajal proclaimed the neuron doctrine based on circuit features he exemplified using cerebellar basket cell projections. Basket cells form dense inhibitory plexuses that wrap Purkinje cell somata and terminate as pinceaux at the initial segment of
Joy Zhou   +5 more
doaj   +1 more source

A computational passage-of-time model of the cerebellar Purkinje cell in eyeblink conditioning

open access: yesFrontiers in Computational Neuroscience, 2023
The cerebellar Purkinje cell controlling eyeblinks can learn, remember, and reproduce the interstimulus interval in a classical conditioning paradigm. Given temporally separated inputs, the cerebellar Purkinje cell learns to pause its tonic inhibition of
Matthew Ricci   +2 more
doaj   +1 more source

Differential synapse density between Purkinje cell dendritic spine and parallel fiber varicosity in the rat cerebellum among the phylogenic lobules

open access: yesApplied Microscopy, 2020
The cerebellum is a region of the brain that plays an important role in motor control. It is classified phylogenetically into archicerebellum, paleocerebellum and neocerebellum.
Hyun-Wook Kim   +4 more
doaj   +1 more source

Basket to Purkinje Cell Inhibitory Ephaptic Coupling Is Abolished in Episodic Ataxia Type 1 [PDF]

open access: yes, 2023
Dominantly inherited missense mutations of the KCNA1 gene, which encodes the KV1.1 potassium channel subunit, cause Episodic Ataxia type 1 (EA1).
Henry G. S. Martin, Dimitri M. Kullmann
core   +1 more source

Cerebellar Purkinje cells incorporate immunoglobulins and immunotoxins in vitro: implications for human neurological disease and immunotherapeutics

open access: yesJournal of Neuroinflammation, 2009
Background Immunoglobulin G (IgG) antibodies reactive with intracellular neuronal proteins have been described in paraneoplastic and other autoimmune disorders.
Rose John W   +4 more
doaj   +1 more source

Serotonin drives a novel GABAergic synaptic current recorded in rat cerebellar purkinje cells: a lugaro cell to purkinje cell synapse [PDF]

open access: yes, 2003
We recorded a novel fast GABAergic synaptic current in cerebellar Purkinje cells in rat brain slices using patch-clamp techniques. Because of a relatively low sensitivity to bicuculline, these currents can be recorded under conditions in which basket and
Isabel Dean   +5 more
core   +1 more source

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