Results 91 to 100 of about 5,279,387 (270)

Non‐Alzheimer Aβ deposits in the human CNS: Implications with hypoxia and related conditions

Brain Pathology, EarlyView.
An Aβ deposit in a non‐Alzheimer's brain from an individual who experienced hypoxia/energy failure. Abstract We recently reported the deposition of Aβ in the frontal cortex of individuals who died of acute coronavirus disease 2019 (COVID‐19), or who did not have COVID‐19 but had respiratory distress, or infants with severe cardiac malformations.
Esma Karlovich, David S. Priemer, Charles Harker Rhodes, Daniel P. Perl, Kurenai Tanji, James E. Goldman   +5 more
wiley   +1 more source

Neurosteroid Biosynthesis and Action in the Purkinje Cell

Journal of Experimental Neuroscience, 2009
It is now clearly established that steroids can be synthesized de novo by the vertebrate brain. Such steroids are called neurosteroids. To understand neurosteroid action in the brain, data on the regio- and temporal-specific synthesis of neurosteroids ...
Kazuyoshi Tsutsui
doaj   +1 more source

Cerebellar LTD and pattern recognition by Purkinje cells

, 2007
Many theories of cerebellar function assume that long-term depression (LTD) of parallel fiber (PF) synapses enables Purkinje cells to learn to recognize PF activity patterns.
De Zeeuw, C., De Zeeuw, Chris I., Mittmann, W., Hoebeek, Freek, Silver, RA, Steuber, V, H\ue4usser, Michael, de Zeeuw, Chris, Steuber, V., Hoebeek, F., Mittmann, Wolfgang, Silver, R. Angus, Silver, R., De Schutter, Erik, Hausser, Michael, Häusser, M., Mittmann, W, De Schutter, E, Steuber, Volker, Hoebeek, Freek E., De Schutter, E., Hausser, M   +21 more
core   +1 more source

Profound morphological and functional changes of rodent Purkinje cellsbetween the first and the second postnatal weeks: a metamorphosis?

Frontiers in Neuroanatomy, 2012
Between the first and the second postnatal week, the development of rodent Purkinje cells is characterized by several profound transitions. Purkinje cells acquire their typical dendritic espalier tree morphology and form distal spines.
Isabelle eDusart, Frédéric eFLAMANT
doaj   +1 more source

Response of the Purkinje cell population under MLI control durign lateral granular layer stimulation

, 2022
Response of the Purkinje cell population under MLI control durign lateral granular layer ...
Robin De Schepper
core   +1 more source

Chronic traumatic encephalopathy in a neuropathologically confirmed Creutzfeldt–Jakob disease cohort

Brain Pathology, EarlyView.
Systematic neuropathological screening of 212 patients with Creutzfeldt–Jakob disease (55% women) identified chronic traumatic encephalopathy in three cases (1.4%), all men with a history of contact sports. These findings represent the first neuropathologically confirmed chronic traumatic encephalopathy cases reported in Spain.
Lluc Bertran, Iban Aldecoa, Arlène Sindikubwabo, Núria Vidal, Rafael Blesa, Mercè Martínez‐Corral, Carlos Nos, Verónica Santiago, Andrea González, Álex Iranzo, Christopher J. Nowinski, Ann C. McKee, Raquel Sánchez Valle, Laura Molina‐Porcel   +13 more
wiley   +1 more source

Labeled Purkinje cell axonal boutons after FL lentivirus injections.

, 2016
Labeled Purkinje cell axonal boutons after FL lentivirus injections.
Ryuichi Shigemoto (90312), Akiya Watakabe (304124), Hitomi Matsuno (701661), Soichi Nagao (189660), Moeko Kudoh (265843), Tetsuo Yamamori (105711)   +5 more
core   +1 more source

The endocytic adaptor AP-2 maintains Purkinje cell function by balancing cerebellar parallel and climbing fiber synapses

Cell Reports
Summary: The loss of cerebellar Purkinje cells is a hallmark of neurodegenerative movement disorders, but the mechanisms remain enigmatic. We show that endocytic adaptor protein complex 2 (AP-2) is crucial for Purkinje cell survival. Using mouse genetics,
Marianna Tolve, Janine Tutas, Ebru Özer-Yildiz, Ines Klein, Anne Petzold, Veronika J. Fritz, Melina Overhoff, Quinn Silverman, Ellie Koletsou, Filip Liebsch, Guenter Schwarz, Tatiana Korotkova, Silvana Valtcheva, Graziana Gatto, Natalia L. Kononenko   +14 more
doaj   +1 more source

A note on the definition and the development of cerebellar purkinje cell zones [PDF]

, 2012
The definition of Purkinje cell zones by their white matter comprtments, their physiological properties, and their molecular identity and the birthdate of their Purkinje cells will be ...
Voogd, J. (Jan), J. Voogd
core   +1 more source

Chd4 and ThPOK cooperate to preserve structural and electrophysiological integrity of the adult heart through Sprr1a repression

The FEBS Journal, EarlyView.
Chd4/NuRD and ThPOK cooperate to maintain transcriptional repression and nuclear organization in adult cardiomyocytes. Chd4 loss reduces miR‐150‐5p, relieving repression of Sprr1a, while ThPOK loss further enhances Sprr1a activation, possibly through altered chromatin–lamina interactions.
Fadoua El Abdellaoui‐Soussi, Apolonia Novillo, Rocío Brea, Marta Ysbert, Lorena Cussó, Gonzalo Pizarro‐Sánchez, Manuel Desco, Iván Hernández, Ángel Luis Armesilla, Ignacio Pérez de Castro, Alicia R. Folgueras, Juan Miguel Redondo, Pablo Gómez‐del Arco   +12 more
wiley   +1 more source