Results 31 to 40 of about 10,772,524 (242)

Microcircuit Rules Governing Impact of Single Interneurons on Purkinje Cell Output In Vivo

open access: yesCell Reports, 2020
Summary: The functional impact of single interneurons on neuronal output in vivo and how interneurons are recruited by physiological activity patterns remain poorly understood.
Charlotte Arlt, Michael Häusser
doaj   +1 more source

Cerebellar Cortex, Purkinje Cell Layer [PDF]

open access: yes, 2008
This report contains a summary of expression patterns for genes that are enriched in the Purkinje cell layer (CBXpu) of the cerebellum. All data is derived from the Allen Brain Atlas (ABA) in situ hybridization mouse project.
Allen Institute for Brain Science   +3 more
core   +2 more sources

Calcium Signaling, PKC Gamma, IP3R1 and CAR8 Link Spinocerebellar Ataxias and Purkinje Cell Dendritic Development

open access: yesCurrent Neuropharmacology, 2017
Background Spinocerebellar ataxias (SCAs) are a group of cerebellar diseases characterized by progressive ataxia and cerebellar atrophy. Several forms of SCAs are caused by missense mutations or deletions in genes related to calcium signaling in Purkinje
Etsuko Shimobayashi, J. Kapfhammer
semanticscholar   +1 more source

Establishment of topographic circuit zones in the cerebellum of scrambler mutant mice

open access: yesFrontiers in Neural Circuits, 2013
The cerebellum is organized into zonal circuits that are thought to regulate ongoing motor behavior. Recent studies suggest that neuronal birthdates, gene expression patterning, and apoptosis control zone formation.
Stacey L Reeber   +3 more
doaj   +1 more source

Spiral-wave dynamics in a mathematical model of human ventricular tissue with myocytes and Purkinje fibers [PDF]

open access: yes, 2017
We present systematic numerical studies of the possible effects of the coupling of human endocardial and Purkinje cells at cellular and two-dimensional tissue levels.
Nayak, Alok Ranjan   +2 more
core   +1 more source

Purkinje-cell-specific DNA repair-deficient mice reveal that dietary restriction protects neurons by cell-intrinsic preservation of genomic health

open access: yesFrontiers in Aging Neuroscience, 2023
Dietary restriction (DR) is a universal anti-aging intervention, which reduces age-related nervous system pathologies and neurological decline. The degree to which the neuroprotective effect of DR operates by attenuating cell intrinsic degradative ...
María Björk Birkisdóttir   +12 more
doaj   +1 more source

Lack of NMDA receptor subunit exchange alters Purkinje cell dendritic morphology in cerebellar slice cultures [PDF]

open access: yes, 2005
Early postnatal developmental changes in N-methyl-D-aspartate (NMDA) receptor (NR) subunits regulate cerebellar granule cell maturation and potentially Purkinje cell development.
Eisel, ULM   +3 more
core   +2 more sources

Fear conditioning-related changes in cerebellar Purkinje cell activities in goldfish

open access: yesBehavioral and Brain Functions, 2012
Background Fear conditioning-induced changes in cerebellar Purkinje cell responses to a conditioned stimulus have been reported in rabbits. It has been suggested that synaptic long-term potentiation and the resulting increases in firing rates of Purkinje
Yoshida Masayuki, Kondo Hiroki
doaj   +1 more source

Olig2/Plp-positive progenitor cells give rise to Bergmann glia in the cerebellum. [PDF]

open access: yes, 2013
NG2 (nerve/glial antigen2)-expressing cells represent the largest population of postnatal progenitors in the central nervous system and have been classified as oligodendroglial progenitor cells, but the fate and function of these cells remain ...
Chung, S-H   +4 more
core   +2 more sources

Autistic-like behavior and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice

open access: yesNature, 2012
Autism spectrum disorders (ASDs) are highly prevalent neurodevelopmental disorders, but the underlying pathogenesis remains poorly understood. Recent studies have implicated the cerebellum in these disorders, with post-mortem studies in ASD patients ...
Peter T. Tsai   +9 more
semanticscholar   +1 more source

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