Results 181 to 190 of about 4,781,201 (273)
Geometric exchange between dendritic spines and shafts is often neglected, yet it exhibits the same signature as permeative exchange, biasing NEXI/SMEX measurements. We propose two models: an extended three‐compartment Kärger model that resolves spine–shaft exchange explicitly, and a coarse‐grained Kärger model that absorbs spines into an effective ...
Kadir Şimşek +3 more
wiley +1 more source
A neural language for the cerebellum: control of behavior via competing populations of Purkinje cells. [PDF]
Shadmehr R, Fakharian MA.
europepmc +1 more source
ABSTRACT Background and Purpose Falls affect approximately half of individuals with chronic obstructive pulmonary disease (COPD) and are associated with hospitalization, accelerated functional decline, and early institutionalization. Existing evidence suggests that single‐visit assessments have limited and inconsistent ability to predict the future ...
Danielle Ferreira de Santana Silva +5 more
wiley +1 more source
Increased reluctant vesicles underlie synaptic depression by GPR55 in axon terminals of rat cerebellar Purkinje cells. [PDF]
Inoshita T, Kawaguchi SY.
europepmc +1 more source
ABSTRACT Aim Repeated heat exposure may promote adaptive remodeling or cumulative tissue burden depending on thermal dose, but its graded molecular and functional consequences during recovery remain unclear. We examined whether repeated moderate (39°C) and severe (41°C) whole‐body hyperthermia produce distinct skeletal muscle trajectories involving ...
Cansu Yakin +4 more
wiley +1 more source
Developmental transformations of Purkinje cells tracked by DNA electrokinetic mobility. [PDF]
Brandenburg C +10 more
europepmc +1 more source
Synaptic Proteostasis in Health and Disease
The localised creation and degradation of proteins at the pre and postsynaptic terminal are processes that are crucial for neuronal homeostasis. Synaptic proteostasis pathways are frequently reported as dysregulated in neurodevelopmental and neurodegenerative disorders.
Paul G. Donlin‐Asp, Emma L. Clayton
wiley +1 more source
The spiny relationship between parallel fibers, climbing fibers, and Purkinje cells. [PDF]
Masoli S +3 more
europepmc +1 more source
An eikonal model with re‐excitability for fast simulations in cardiac electrophysiology
Abstract figure legend Restitution properties obtained from cable‐equation simulations and anisotropic remeshing informed by local fibre orientation are combined in an eikonal model with re‐excitability. The resulting reduced electrophysiology model enables efficient simulations of recurrent activation patterns, here illustrated by atrial re‐entry ...
Lia Gander +3 more
wiley +1 more source
Autonomous STING signaling in Purkinje cells drives neurodegeneration independent of type I interferon. [PDF]
Yang K +5 more
europepmc +1 more source

