Results 81 to 90 of about 4,460,775 (261)

Purkinje cells and their trees

open access: yesThe Lancet Neurology, 2021
Zoghbi, Huda Y, Mehta, Arpan R
openaire   +4 more sources

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

open access: yesIbrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

Processing of Visual Signals Related to Self-motion in the Cerebellum of Pigeons

open access: yesFrontiers in Behavioral Neuroscience, 2013
In this paper I describe the key features of optic flow processing in pigeons. Optic flow is the visual motion that occurs across the entire retina as a result of self-motion and is processed by subcortical visual pathways that project to the cerebellum.
Douglas Richard Wylie
doaj   +1 more source

Role of Cytosolic Calcium Diffusion in Murine Cardiac Purkinje Cells

open access: yes, 2016
Cardiac Purkinje cells (PCs) are morphologically and electrophysiologically different from ventricular myocytes and, importantly, exhibit distinct calcium (Ca 2+ ) homeostasis. Recent studies suggest that PCs are more susceptible to action potential (AP)
Makar   +5 more
core   +1 more source

Dendritic planarity of Purkinje cells is independent of Reelin signaling [PDF]

open access: yes, 2018
The dendritic planarity of Purkinje cells is critical for cerebellar circuit formation. In the absence of Crk and CrkL, the Reelin pathway does not function resulting in partial Purkinje cell migration and defective dendritogenesis.
Kohmura, Y   +9 more
core   +1 more source

Recent Advances in Top‐Down Proteomics for Single‐Cell Research

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Individual cells have distinctive molecular characteristics, including biologically relevant proteoforms. Although single‐cell (SC) molecular omics offer unprecedented insights into cellular heterogeneity and function, the characterization of proteoforms in SCs remains an uncharted territory.
Jake A. Melby, Pei Su, Fabio P. Gomes
wiley   +1 more source

Type-1 metabotropic glutamate receptor signaling in cerebellar Purkinje cells in health and disease [version 1; referees: 3 approved]

open access: yesF1000Research, 2017
The cerebellum is a brain structure involved in coordination, control, and learning of movements, as well as certain aspects of cognitive function. Purkinje cells are the sole output neurons from the cerebellar cortex and therefore play crucial roles in ...
Masanobu Kano, Takaki Watanabe
doaj   +1 more source

Purkinje cell models: past, present and future

open access: yesFrontiers in Computational Neuroscience
The investigation of the dynamics of Purkinje cell (PC) activity is crucial to unravel the role of the cerebellum in motor control, learning and cognitive processes. Within the cerebellar cortex (CC), these neurons receive all the incoming sensory and motor information, transform it and generate the entire cerebellar output.
Elías Mateo Fernández Santoro   +7 more
openaire   +5 more sources

Dendritic spike induction of postsynaptic cerebellar LTP [PDF]

open access: yes, 2008
The architecture of parallel fiber (PF) axons contacting cerebellar Purkinje neurons (PNs) retains spatial information over long distances. PF synapses can trigger local dendritic calcium spikes, but whether and how this calcium signal leads to plastic ...
Marco Canepari, Kaspar E. Vogt
core  

Purkinje cell microzones mediate distinct kinematics of a single movement [PDF]

open access: yes, 2023
The classification of neuronal subpopulations has significantly advanced, yet its relevance for behavior remains unclear. The highly organized flocculus of the cerebellum, known to fine-tune multi-axial eye movements, is an ideal substrate for the study ...
Schonewille, Martijn   +8 more
core  

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