Results 101 to 110 of about 4,781,201 (273)

Dendritic planarity of Purkinje cells is independent of Reelin signaling [PDF]

open access: yes, 2014
The dendritic planarity of Purkinje cells is critical for cerebellar circuit formation. In the absence of Crk and CrkL, the Reelin pathway does not function resulting in partial Purkinje cell migration and defective dendritogenesis.
Kohmura, Y   +19 more
core   +1 more source

Selective autophagy pathways in ageing and neurodegeneration: Emerging roles for mitophagy and nucleophagy

open access: yesThe FEBS Journal, EarlyView.
As we age, cells gradually accumulate damage, which can contribute to disease and neurodegeneration. This review explores how two cellular recycling processes, mitophagy and nucleophagy, remove damaged mitochondria and nuclear material, respectively, to maintain cell health and long‐term neuronal homeostasis.
Maria Markaki, Nektarios Tavernarakis
wiley   +1 more source

Purkinje cells point cloud

open access: yes, 2015
A list of all localized Purkinje cells in the cerebellum of a P10 L7-GFP mouse. Data are stored in a .csv file format; each line represents a cell, and the 4 columns represent the x,y,z spatial coordinates + a unique cell ...
Silvestri, Ludovico
core   +1 more source

Safety of Pulsed Field Ablation: Established Evidence, Emerging Risks, and Knowledge Gaps

open access: yesPacing and Clinical Electrophysiology, EarlyView.
Overview of the safety profile of pulsed field ablation (PFA), highlighting established safety advantages, procedure‐related complications, electroporation‐specific effects, and key areas of ongoing uncertainty, particularly for ventricular applications.
Dakota de Cecco   +3 more
wiley   +1 more source

Establishment of topographic circuit zones in the cerebellum of scrambler mutant mice

open access: yesFrontiers in Neural Circuits, 2013
The cerebellum is organized into zonal circuits that are thought to regulate ongoing motor behavior. Recent studies suggest that neuronal birthdates, gene expression patterning, and apoptosis control zone formation.
Stacey L Reeber   +3 more
doaj   +1 more source

Differentiation of human induced pluripotent stem cells to Purkinje neurons

open access: yes, 2015
<p>This protocol describes how to differentiate human induced pluripotent stem cells (iPSCs) to Purkinje cells. Human iPSCs are first differentiated to Neph3+ Purkinje progenitors.
sprotocols
core   +1 more source

Cerebrovascular regulation during heat stress

open access: yesExperimental Physiology, EarlyView.
Abstract Given that the brain is a highly metabolic organ and is enclosed by the skull, effective regulation of cerebral blood flow (CBF), not only for oxygen and nutrients supply but also as a means of convective heat exchange, is critical for preventing excessive elevations in brain temperature.
Kanoko Ito, Manabu Shibasaki
wiley   +1 more source

Quantitative organization of GABAergic synapses in the molecular layer of the mouse cerebellar cortex.

open access: yesPLoS ONE, 2010
In the cerebellar cortex, interneurons of the molecular layer (stellate and basket cells) provide GABAergic input to Purkinje cells, as well as to each other and possibly to other interneurons.
Federica Briatore   +4 more
doaj   +1 more source

lnteractions between cerebellar Purkinje cells and their associated astrocytes [PDF]

open access: yes, 2001
Some neurons, including cerebellar Purkinje cells, are completely ensheathed by astrocytes. When granule cell neurons and functional glia were eliminated from newborn mouse cerebellar cultures by initial exposure to a DNA synthesis inhibitor ...
Seil, F.J.
core  

Spontaneous postsynaptic currents in Purkinje cells.

open access: yes, 2014
(A) Representative traces of spontaneous EPSCs and IPSCs in control and Cstb−/− Purkinje cells. EPSCs are seen as inward currents (downward deflections) and IPSCs are seen as outward currents (upward deflections). Insets show single IPSCs and EPSCs taken
Saara Tegelberg (528575)   +11 more
core   +1 more source

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