Results 41 to 50 of about 789 (216)

Switching target communication strategy for optimizing multiple pursuer drones performance in immobilizing Kamikaze multiple evader drones

ICT Express, 2020
We propose a method for optimizing multiple-drone pursuers’ performance in handling attacks from Kamikaze multiple-drone evaders on a battlefield. The central aspect of this problem is to minimize damage produced by evaders towards a defended area ...
Ario Yudo Husodo, Grafika Jati, Amarulla Octavian, Wisnu Jatmiko   +3 more
doaj   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

An Overview of Recent Advances in Pursuit–Evasion Games with Unmanned Surface Vehicles

Journal of Marine Science and Engineering
With the rapid development of perception, decision-making, and control technologies, pursuit–evasion (PE) games with unmanned surface vehicles (USVs) have become an interesting research topic in military implementations and civilian areas. In this paper,
Xingru Qu, Linghui Zeng, Shihang Qu, Feifei Long, Rubo Zhang   +4 more
doaj   +1 more source

A Geometrical, Reachable Set Approach for Constrained Pursuit–Evasion Games with Multiple Pursuers and Evaders

Aerospace, 2023
This paper presents a solution strategy for deterministic time-optimal pursuit–evasion games with linear state constraints, convex control constraints, and linear dynamics that is consistent with linearized relative orbital motion models such as the ...
Olli Jansson, Matthew W. Harris
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

An Approach for Solving Discrete Game Problems with Total Constraints on Controls

Abstract and Applied Analysis, 2014
We consider a linear pursuit game of one pursuer and one evader whose motions are described by different-type linear discrete systems. Controls of the players satisfy total constraints.
Asqar Raxmonov, Gafurjan I. Ibragimov
doaj   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Linear Discrete Pursuit Game with Phase Constraints

The Scientific World Journal, 2014
We consider a linear pursuit game of one pursuer and one evader whose motions are described by different-type linear discrete systems. Position of the evader satisfies phase constraints: y∈G, where G is a subset of Rn.
Asqar Raxmanov, Gafurjan Ibragimov
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source