Results 41 to 50 of about 2,277 (292)
Surveillance Strategies for a Pursuer with Finite Sensor Range [PDF]
The International Journal of Robotics Research, 2007 This paper addresses the pursuit-evasion problem of maintaining surveillance by a pursuer of an evader in a world populated by polygonal obstacles. This requires the pursuer to plan colision-free motions that honor distance constraints imposed by sensor capabilities, while avoiding occlusion of the evader by any obstacle.
Rafael Murrieta-Cid +4 more
openaire +2 more sources
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Switching pursuit strategies for multi-pursuer single-evader games [PDF]
This paper introduces a new family of pursuit strategies for multi-pursuer single-evader games in a planar environment. The main idea is to exploit conditions under which capture of the evader in minimum time can be achieved by only two pursuers.
Casini M., Garulli A.
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Noisy pursuit and pattern formation of self-steering active particles
New Journal of Physics, 2022 We consider a moving target and an active pursing agent, modeled as an intelligent active Brownian particle capable of sensing the instantaneous target location and adjusting its direction of motion accordingly.
Segun Goh +2 more
doaj +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Mathematics, 2023 The present paper is devoted to studying a pursuit differential game described by an infinite system of binary differential equations in Hilbert space l2. The control parameters of the players are subject to geometric constraints.
Gafurjan Ibragimov +3 more
doaj +1 more source
Pursuit-evasion games with multi-pursuer vs. one fast evader
, 2010 In a pursuit-evasion (PE) game, each pursuer attempts to minimize the distance between the pursuer (P) and the evader (E) and capture it in the shortest time, whereas the evader tries to maximize the distance to escape from being captured. In this paper,
null Zhihua Qu +3 more
core +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source