Results 141 to 150 of about 829,454 (288)
Recent Advances in Exosome‐Based Nanodelivery Systems for Traumatic Brain Injury Treatment
Med Research, EarlyView.An overview of functional modification, therapeutic effects, molecular composition, and delivery strategies for exosomes. ABSTRACT Traumatic brain injury (TBI) is a highly heterogeneous neurological condition with extremely high rates of mortality and disability.
Jue Zhu +9 more
wiley +1 more source
Counterintuitive prey strategies against predators with finite budgets: protection heterogeneity among sites matters more than their number. [PDF]
J R Soc Interface, 2023 Clémençon P, Alpern S, Gal S, Casas J.
europepmc +1 more source
Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future
Medicinal Research Reviews, EarlyView.ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley +1 more source
Hsp90 Inhibition on the Western Blot: N‐Terminal Versus C‐Terminal Inhibitors in Breast Cancer
Medicinal Research Reviews, EarlyView.ABSTRACT Heat shock protein 90 (Hsp90) is an established and clinically validated anticancer target. By regulating the folding and maturation of diverse client proteins, it is indirectly involved in carcinogenesis. Key breast cancer oncogenic drivers, including estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2, are ...
Jaka Dernovšek +3 more
wiley +1 more source
GUARANTEED STRATEGIES FOR NONLINEAR MULTI-PLAYER PURSUIT-EVASION GAMES
In this paper, we provide a methodology to design strategies for either guaranteed capture or guaranteed evasion in the case of pursuit-evasion games with multiple players which are represented by nonlinear dynamic models.
NAIRA HOVAKIMYAN +2 more
core
International Journal of Mechanical System Dynamics, EarlyView.ABSTRACT The design of control systems for high‐agility mechanical systems operating in extreme environments is a significant challenge in nonlinear dynamics. This paper addresses the complex dynamic control problem of a hypersonic interceptor, modeled as a multi‐input multi‐output (MIMO) mechanical system characterized by strong aerodynamic cross ...
Mohammad Mahdi Soori +1 more
wiley +1 more source
Optimal-Damage-Effectiveness Cooperative-Control Strategy for the Pursuit-Evasion Problem with Multiple Guided Missiles. [PDF]
Sensors (Basel), 2022 Ma X +7 more
europepmc +1 more source
Catechins and Their Effect on the Gut Microbiome in Health and Cancer
Phytotherapy Research, EarlyView.ABSTRACT Catechins are a group of flavonoids found primarily in green tea, fruits, and berries; they play a significant role in the modulation of the gut microbiota, thereby having an impact on gut health and cancer prevention. Owing to their low bioavailability, catechins are transformed by the gut microbiota into various bioactive metabolites such as
Prakash Monika +5 more
wiley +1 more source
, 2015 This tutorial contains tools and techniques for designing pursuit and evasion strategies. The material targets a diverse audience including STEM educators as well as robotics researchers interested in applications of pursuit-evasion games. We start
Isler, Volkan +2 more
core
The Transformational STEM Consciousness Scale: A QuantCrit Measure of a Liberatory STEM Outcome
Science Education, EarlyView.ABSTRACT Guided by QuantCrit, we introduce and validate the Transformational STEM Consciousness (TSC) scale, which fuses students' motivation to pursue racial and social justice through STEM with a critique of STEM's historic complicity in inequity. Surveying 255 undergraduate and graduate students in 18 justice‐integrated STEM courses across 11 US ...
Juan C. Garibay, Lindsay Wheeler
wiley +1 more source