Results 51 to 60 of about 749,971 (303)

Impact of hydrogen on the high cycle fatigue behaviour of Inconel 718 in asymmetric push–pull mode at room temperature

, 2015
The influence of hydrogen on the high cycle fatigue (HCF) behaviour of Inconel 718 has been studied at room temperature in asymmetric push–pull mode using an ultrasonic HCF test rig. Fatigue tests have been carried out in gaseous hydrogen (GH2) and in Ar
Fischer, B., Gonzalez Sanchez, Sergio, Ruiz, A., Bruchhausen, M., Hähner, P., Fischer, Burkhard, Soller, S., Bruchhausen, Matthias, Hähner, Peter, González, S., Soller, Sebastian   +10 more
core   +1 more source

Insight into single-fiber push-out test of tungsten fiber-reinforced tungsten [PDF]

, 2019
To overcome the intrinsic brittleness of tungsten (W), a tungsten fiber-reinforced tungsten-composite material (Wf/W) is a possible solution. The introduction of energy dissipation mechanisms like fiber bridging or fiber pull-out by means of an ...
Riesch, Johann, Coenen, Jan Willem, Du, J., Jasper, Bruno, Natour, G., Neu, R., Schönen, S., Neu, Rudolf, Coenen, J., Linsmeier, Christian, Schönen, Stephan, Linsmeier, C., Du, Juan, Höschen, T., Riesch, J., Natour, Ghaleb, Höschen, Till, Jasper, B.   +17 more
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati, Sami I. Nassar, Shaun A. Nguyen, Patricia L. Gerend, Michael C. Schubert, Michael T. Teixido, Frederick A. Godley, Joel A. Goebel, Cynthia A. Ryan, Habib G. Rizk, Amir Kheradmand   +10 more
wiley   +1 more source

Numerical analysis of frictional contact effects in push-out tests [PDF]

Engineering Structures, 2012
This paper proposes an accurate and efficient 2D nonlinear finite element model to investigate the mechanical behaviour of the shear connection between prefabricated concrete slab and steel girder in composite bridges. Beside material nonlinear constitutive laws and 4-noded plane elements, frictional contact finite elements are introduced in the model ...
Guezouli, Samy, Lachal, Alain
openaire   +2 more sources

Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu, Xiaoning Ren, Cuihua Fan, Chun Li, Lijie Zhang, Zaiqiang Zhang, Shaowu Li, Zhongmeng Lai, Bin Cai, Ying Fu, Yi Lin, Zhibao Zhu   +11 more
wiley   +1 more source

Nanomaterial-Enhanced Sizings: Design and Optimisation of a Pilot-Scale Fibre Sizing Line

Fibers
This study focuses on the development of a pilot-scale sizing line, including its initial design and installation, operational phases, and optimization of key process parameters.
Dionisis Semitekolos, Ioannis Papadopoulos, Stavros Anagnou, Behnam Dashtbozorg, Xiaoying Li, Hanshan Dong, Costas A. Charitidis   +6 more
doaj   +1 more source

Artificial Intelligence–Based Online Symptom Assessment Tools for Systemic Lupus Erythematosus Diagnosis: Patient Perspectives

Arthritis Care &Research, EarlyView.
Objective The objective of this article is to identify perceptions of patients with systemic lupus erythematosus (SLE) regarding artificial intelligence (AI)–based online symptom assessment tools, and the potential of these tools to address diagnostic barriers.
Olivia A. Stein, Jennifer L. F. Lee, Evelyne Vinet, Arielle Mendel, Christian A. Pineau, Fares Kalache, Louis‐Pierre Grenier, Sasha Bernatsky   +7 more
wiley   +1 more source

Behaviour and Strength of Headed Shear Stud Connectors

Communications, 2013
Headed stud shear connectors are commonly used to transfer longitudinal shear forces across the steel-concrete interface in composite structures. This paper is focused on the experimental and numerical study on the behaviour of this type of connectors ...
Patricia Duratna, Jan Bujnak, Abdelhamid Bouchair, Frantisek Bahleda   +3 more
doaj   +1 more source