Spatial and Temporal Evolutionary Patterns in Puumala Orthohantavirus (PUUV) S Segment. [PDF]
The S segment of bank vole (Clethrionomys glareolus)-associated Puumala orthohantavirus (PUUV) contains two overlapping open reading frames coding for the nucleocapsid (N) and a non-structural (NSs) protein.
Binder F +10 more
europepmc +6 more sources
Genetic Diversity of Puumala orthohantavirus in Rodents and Human Patients in Austria, 2012-2019. [PDF]
Puumala orthohantavirus (PUUV) has a wide distribution throughout Europe. Distinctive temporal patterns of spillover into the human population are related to population dynamics of the reservoir host, the bank vole (Clethrionomys glareolus).
Camp JV +5 more
europepmc +5 more sources
Comparison of Lymphocyte Populations in Patients With Dobrava or Puumala orthohantavirus Infection. [PDF]
Hemorrhagic fever with renal syndrome (HFRS), caused by Dobrava (DOBV) and Puumala (PUUV) orthohantaviruses, is an endemic disease in Slovenia. DOBV is mainly responsible for a more severe disease, whereas PUUV usually causes a milder form.
Resman Rus K +5 more
europepmc +5 more sources
Designing a Conserved Immunogenic Peptide Construct from the Nucleocapsid Protein of <i>Puumala orthohantavirus</i>. [PDF]
Puumala orthohantavirus (PUUV) is an emerging zoonotic virus endemic to Europe and Russia that causes nephropathia epidemica, a mild form of hemorrhagic fever with renal syndrome (HFRS).
Sehgal A +9 more
europepmc +4 more sources
Impact of Landscape on Host-Parasite Genetic Diversity and Distribution Using the Puumala orthohantavirus-Bank Vole System. [PDF]
In nature, host specificity has a strong impact on the parasite’s distribution, prevalence, and genetic diversity. The host’s population dynamics is expected to shape the distribution of host-specific parasites.
Razzauti M, Castel G, Cosson JF.
europepmc +6 more sources
Small mammal community composition impacts bank vole (Clethrionomys glareolus) population dynamics and associated seroprevalence of Puumala orthohantavirus [PDF]
Rodents are important reservoirs for zoonotic pathogens that cause diseases in humans. Biodiversity is hypothesized to be closely related to pathogen prevalence through multiple direct and indirect pathways.
Bujnoch, Felicitas Maria +6 more
core +4 more sources
Circulating mucosal-like IgA responses increase with severity of Puumala orthohantavirus-caused hemorrhagic fever with renal syndrome. [PDF]
Old World Orthohantaviruses cause hemorrhagic fever with renal syndrome (HFRS) characterized by increased vascular permeability and acute kidney injury (AKI).
Cabrera LE +10 more
europepmc +6 more sources
Use of a diagnostic Puumala virus real-time RT-PCR in an orthohantavirus endemic region in the Netherlands. [PDF]
Laboratory diagnosis of orthohantavirus infection is primarily based on serology. However, for a confirmed serological diagnosis, evaluation of a follow-up serum sample is essential, which is time consuming and causes delay.
Geeraedts F +9 more
europepmc +5 more sources
Long-Term Consequences of Puumala Hantavirus Infection [PDF]
Several viral infections are associated with acute and long-term complications. During the past two years, there have been many reports on post-infectious symptoms of the patients suffering from COVID-19 disease.
Jukka Mustonen +3 more
doaj +5 more sources
Heterogeneous Puumala orthohantavirus situation in endemic regions in Germany in summer 2019 [PDF]
Puumala orthohantavirus (PUUV) causes most human hantavirus disease cases in Europe. PUUV disease outbreaks are usually synchronized Germany-wide driven by beech mast-induced irruptions of its host (bank vole, Myodes glareolus). Recent data indicate high
Below, Diana Alexandra +13 more
core +4 more sources

