Results 71 to 80 of about 5,277 (210)

Sequential assessment of clinical and laboratory parameters in patients with hemorrhagic fever with renal syndrome. [PDF]

open access: yesPLoS ONE, 2018
BACKGROUND:Information on the sequential appearance, duration, and magnitude of clinical and laboratory parameters in hemorrhagic fever with renal syndrome (HFRS) is limited.
Emil Pal   +7 more
doaj   +1 more source

Antibody feedback regulation

open access: yesImmunological Reviews, Volume 328, Issue 1, Page 126-142, November 2024.
Summary Antibodies are able to up‐ or downregulate antibody responses to the antigen they bind. Two major mechanisms can be distinguished. Suppression is most likely caused by epitope masking and can be induced by all isotypes tested (IgG1, IgG2a, IgG2b, IgG3, IgM, and IgE).
Birgitta Heyman
wiley   +1 more source

Puumala and Tula Virus Differ in Replication Kinetics and Innate Immune Stimulation in Human Endothelial Cells and Macrophages

open access: yesViruses, 2019
Old world hantaviruses cause hemorrhagic fever with renal syndrome (HFRS) upon zoonotic transmission to humans. In Europe, the Puumala virus (PUUV) is the main causative agent of HFRS.
Daniel Bourquain   +3 more
doaj   +1 more source

Hantavirus infection-induced B cell activation elevates free light chains levels in circulation.

open access: yesPLoS Pathogens, 2021
In humans, orthohantaviruses can cause hemorrhagic fever with renal syndrome (HFRS) or hantavirus pulmonary syndrome (HPS). An earlier study reported that acute Andes virus HPS caused a massive and transient elevation in the number of circulating ...
Jussi Hepojoki   +11 more
doaj   +1 more source

Case report: Hemorrhagic fever with renal syndrome presenting as hemophagocytic lymphohistiocytosis

open access: yesFrontiers in Medicine, 2022
Hemophagocytic lymphohistiocytosis may occur in patients with genetic predisposition and in sporadic cases due to malignancy or infection. We describe a 49-year old man with hemorrhagic fever, type 1 respiratory insufficiency and acute kidney injury ...
Maarten A. J. De Smet   +5 more
doaj   +1 more source

Interferon-stimulated gene (ISG)-expression screening reveals the specific antibunyaviral activity of ISG20 [PDF]

open access: yes, 2018
Bunyaviruses pose a significant threat to human health, prosperity and food security. In response to viral infections, interferons (IFNs) upregulate the expression of hundreds of interferon stimulated genes (ISGs) whose cumulative action can potently ...
Bieniasz, Paul D.   +15 more
core   +1 more source

In silico design and evaluation of a multiepitope vaccine targeting the nucleoprotein of Puumala orthohantavirus

open access: yesProteins: Structure, Function, and Bioinformatics, Volume 92, Issue 10, Page 1161-1176, October 2024.
Abstract The Puumala orthohantavirus is present in the body of the bank vole (Myodes glareolus). Humans infected with this virus may develop hemorrhagic fever accompanying renal syndrome. In addition, the infection may further lead to the failure of an immune system completely.
Kunal Bhattacharya   +4 more
wiley   +1 more source

Analytical Performance of the RIDASCREEN® Hantavirus Puumala IgG/IgM ELISA Assay

open access: yesViruses, 2020
The National Reference Center for Hantavirus in Belgium is currently using the Hantavirus IgM/IgG ELISA Progen kit (Heidelberg, Germany) for the detection of the most prevalent Hantavirus in Western Europe, Puumala virus (PUUV).
Melissa Depypere   +4 more
doaj   +1 more source

The pathogenesis of zoonotic viral infections: Lessons learned by studying reservoir hosts

open access: yesFrontiers in Microbiology, 2023
Zoonotic viral infections that cause severe disease or even death in some people may be asymptomatic or mild in reservoir hosts. Comparison of the pathogenesis of these two host categories may potentially explain the difference in disease.
Lineke Begeman   +4 more
doaj   +1 more source

Dendritic Cells (DCs) as "Fire Accelerants" of Hantaviral Pathogenesis [PDF]

open access: yes, 2019
Hantaviruses are widespread zoonotic pathogens found around the globe. Depending on their geographical location, hantaviruses can cause two human syndromes, haemorrhagic fever with renal syndrome (HFRS) or hantavirus pulmonary syndrome (HPS).
Raftery, Martin J., Schönrich, Günther
core   +1 more source

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