Results 41 to 50 of about 70,518 (282)

Combination of PD-L1 and PVR determines sensitivity to PD-1 blockade.

open access: yesJCI Insight, 2020
Expression of immune checkpoint ligands (ICLs) is necessary to trigger the inhibitory signal via immune checkpoint receptors (ICRs) in exhausted T cells under tumor immune microenvironment.
Bo Ryeong Lee   +10 more
semanticscholar   +1 more source

Evaluation of Rational Use of Medications in the United States

open access: yesJournal of Primary Care & Community Health, 2010
Rational medication use means taking medication appropriately for curing and relieving the symptoms of disease on the basis of evidence and sound judgment. We compare US policy experience on rational use of medications with the World Health Organization (
Lincy Subha Lal PharmD, PhD   +1 more
doaj   +1 more source

Postvoid Residual Volume Correlates With Bladder Outlet Obstruction and Not With Detrusor Contraction Strength Parameters in Women: A Matched Case-Control Study [PDF]

open access: yesInternational Neurourology Journal
Purpose To compare voiding parameters in women with and without increased postvoid residual (PVR) volume, to correlate these parameters with PVR volume and PVR percentage, and to describe their ability to predict an increased PVR volume.
Juan Pablo Valdevenito   +4 more
doaj   +1 more source

Repositioning liothyronine for cancer immunotherapy by blocking the interaction of immune checkpoint TIGIT/PVR

open access: yesCell Communication and Signaling, 2020
Inhibitors targeting immune checkpoint were proved effective in cancer immunotherapy, such as PD-1/PD-L1 blockade. The novel immune checkpoint TIGIT/PVR plays critical roles in suppressing the anti-tumor effects of CD8+ T and NK cells, and dual blockade ...
Xiuman Zhou   +12 more
semanticscholar   +1 more source

Echocardiography combined with cardiopulmonary exercise testing for the prediction of outcome in idiopathic pulmonary arterial hypertension [PDF]

open access: yes, 2016
BACKGROUND: Right ventricular (RV) function is a major determinant of exercise intolerance and outcome in idiopathic pulmonary arterial hypertension (IPAH). The aim of the study was to evaluate the incremental prognostic value of echocardiography of the
Badagliacca, Roberto   +11 more
core   +1 more source

Bone Marrow Stromal Cell-Derived IL-8 Upregulates PVR Expression on Multiple Myeloma Cells via NF-kB Transcription Factor

open access: yesCancers, 2020
Bone marrow stromal cells (BMSCs) strongly contribute to multiple myeloma (MM) progression, promoting the survival and growth of malignant plasma cells (PCs).
Abdelilah Mekhloufi   +15 more
semanticscholar   +1 more source

Three dimensional extension of Bresenham’s algorithm with Voronoi diagram [PDF]

open access: yes, 2010
Bresenham’s algorithm for plotting a two-dimensional line segment is elegant and efficient in its deployment of mid-point comparison and integer arithmetic. It is natural to investigate its three-dimensional extensions.
Au, Chi Kit, Woo, Tony
core   +2 more sources

Right ventricular outflow tract velocity time integral-to-pulmonary artery systolic pressure ratio: a non-invasive metric of pulmonary arterial compliance differs across the spectrum of pulmonary hypertension. [PDF]

open access: yes, 2019
Pulmonary arterial compliance (PAC), invasively assessed by the ratio of stroke volume to pulmonary arterial (PA) pulse pressure, is a sensitive marker of right ventricular (RV)-PA coupling that differs across the spectrum of pulmonary hypertension (PH ...
Bhattacharya, Priyanka T.   +15 more
core   +2 more sources

The IgV domain of the poliovirus receptor alone is immunosuppressive and binds to its receptors with comparable affinity

open access: yesScientific Reports, 2023
PVR (poliovirus receptor) functions as a ligand that signals through TIGIT and CD96 to induce suppression of T-cell and NK-cell responses. Alternatively, PVR binds to CD226, resulting in a co-stimulatory signal.
Shrayasee Saha   +4 more
doaj   +1 more source

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