Results 1 to 10 of about 1,280 (161)
Albinism and human rights: From marginalisation to global advocacy [PDF]
African Journal of DisabilityBackground: Persons with albinism (PWAs) face significant biological, social and structural challenges, particularly in Africa, where entrenched cultural myths and systemic discrimination expose them to violence, stigma and exclusion.
Tameshnie Deane
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Extending Biopython to combine multiple sequence alignments with the same reference into a Multiple Sequence Alignment. [PDF]
microPublication BiologyPairwise alignments (PWAs) are commonly used to compare sequences to a reference. Existing alignment tools provide algorithms to align multiple sequences to a single reference and to merge two sets of aligned sequences; but not to combine individually ...
Cassia Bastress +3 more
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Cell-type-aware transcriptome-wide association studies identify 91 independent risk genes for Alzheimer’s disease dementia [PDF]
Communications BiologyMost existing transcriptome wide association studies (TWASs) of Alzheimer’s Disease (AD) dementia only use bulk RNA-seq data and a single statistical method.
Qiang Liu +9 more
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Transcriptome and plasma proteome analyses identify susceptibility genes and proteins for alcohol-related hepatocellular carcinoma [PDF]
Human GenomicsBackground Genome-wide association studies (GWAS) have identified loci associated with alcohol-related hepatocellular carcinoma (ALD-HCC); however, most risk variants lie in noncoding regions and the downstream regulatory architecture remains ...
Zhishuang Li +9 more
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Identification and validation of novel risk genes for intervertebral disc disorder by integrating large-scale multi-omics analyses and experimental studies [PDF]
Frontiers in MedicineIntroductionAlthough genome-wide association studies (GWAS) have identified multiple genetic loci linked to intervertebral disc disorder (IDD), their functional characterization remains largely unelucidated.
Zhe Zhang +9 more
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European Psychiatry, 2023 Objective Genetic approaches are increasingly advantageous in characterizing treatment-resistant schizophrenia (TRS). We aimed to identify TRS-associated functional brain proteins, providing a potential pathway for improving psychiatric classification ...
Wenming Wei +13 more
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Evaluating Progressive Web App Accessibility for People with Disabilities
Network, 2022 App development is a steadily growing industry. Progressive web apps (PWAs) constitute a technology inspired by native and hybrid apps; they use web technologies to create web and mobile apps.
Konstantinos I. Roumeliotis +1 more
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Brain Sciences, 2021 Recently, a multilevel analytic approach called Main Concept, Sequencing, and Story Grammar (MSSG) was presented along with preliminary normative information.
Jessica D. Richardson +5 more
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Genome Biology, 2020 We introduce Proteome-Wide Association Study (PWAS), a new method for detecting gene-phenotype associations mediated by protein function alterations. PWAS aggregates the signal of all variants jointly affecting a protein-coding gene and assesses their ...
Nadav Brandes +2 more
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Computers, 2023 This paper is poised to inform educators, policy makers and software developers about the untapped potential of PWAs in creating engaging, effective, and personalized learning experiences in the field of programming education.
Rytis Maskeliūnas +5 more
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