Results 41 to 50 of about 1,365 (157)

Integrative Analysis of Plasma Proteome and Genome Reveals Novel Drug Targets for Chronic Rhinosinusitis and Nasal Polyps

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) and nasal polyps (NP) are chronic inflammatory conditions with unsatisfactory treatment outcomes due to frequent recurrence of refractory disease. Identifying new therapeutic targets is essential. Methods We conducted a proteome‐wide Mendelian randomization (MR) analysis by integrating genome‐wide ...
En Zhou   +4 more
wiley   +1 more source

Quality of Life Outcomes Following Stroke for People with Aphasia: Perceptions of Patients, Caregivers, and Speech-Language Pathologists

open access: yesApplied Sciences
Introduction: Due to the inherent difficulty in obtaining information using language-based questionnaires, research on the quality of life (QOL) for persons with aphasia (PWAs) is lacking.
Paul M. Evitts   +3 more
doaj   +1 more source

Vascular Dynamics During Respiratory Arousal From Sleep Assessed by Oximeter‐Based Vascular Stiffness Measures

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Cortical arousals significantly impact obstructive sleep apnoea (OSA) pathophysiology and cardiovascular consequences, often mediated by sympathetic activation. While pulse oximetry (PPG) provides an accessible reflection of autonomic responses such as changes in pulse rate (PR) and pulse wave amplitude (PWA), the dynamic influence on other ...
Christian Strassberger   +3 more
wiley   +1 more source

Customized Metal 3D Printed Total Wrist Prosthesis in the Treatment of Severely Destroyed Wrist: Design Rationale and Clinical Applications

open access: yesOrthopaedic Surgery, Volume 17, Issue 5, Page 1536-1546, May 2025.
Four patients with severe wrist destruction from various causes were treated with customized 3D‐printed prostheses. In addition to the specific articular surface matching their original radiocarpal joint, two innovative proximal component designs were created to address different bone defects.
Qipei Wei   +3 more
wiley   +1 more source

Improving the Retention of Low-Volume Autologous Fat Grafting: A Comparative Analysis of Lipoaspirate Processing Techniques for Facial Feminization

open access: yesAesthetic Surgery Journal Open Forum
BackgroundOutcomes following autologous fat grafting have historically been unpredictable because of variability in fat retention rates. The novel poloxamer wash, absorption, mesh filtration system (PWAS) uses proprietary technology to stabilize and ...
Katherine H Carruthers   +6 more
doaj   +1 more source

The effects of uninterrupted and interrupted sitting on blood pressure and arterial stiffness in patients with established coronary heart disease

open access: yesExperimental Physiology, EarlyView.
Abstract Sedentary behaviour is an independent risk factor for cardiovascular disease. In healthy adults, prolonged uninterrupted sitting acutely increases blood pressure (BP) and aortic stiffness; however, these effects can be mitigated with light physical activity interruptions.
Simon Fryer   +7 more
wiley   +1 more source

Cellular transcriptomic signatures underpinning the heterogeneity of depression in Alzheimer's disease

open access: yesAlzheimer's &Dementia, Volume 22, Issue 9, September 2026.
Abstract INTRODUCTION Late‐onset Alzheimer's disease (LOAD) and major depressive disorder (MDD) share genetic etiologies. Here, we investigated brain transcriptomic landscapes to gain insights into shared and divergent molecular and biological etiologies across LOAD and MDD.
Michael W. Lutz   +2 more
wiley   +1 more source

An investigation of the use of co-verbal gestures in oral discourse among Chinese speakers with fluent versus non-fluent aphasia and healthy adults

open access: yesFrontiers in Psychology, 2015
Introduction Co-verbal gestures can facilitate word production among persons with aphasia (PWA) (Rose, Douglas, & Matyas, 2002) and play a communicative role for PWA to convey ideas (Sekine & Rose, 2013).
Anthony Pak Hin Kong, Sampo Law
doaj   +1 more source

Design and Implementation of an AI‐Driven Intelligent Decision Support System for Sustainable Ecotourism Development

open access: yesEngineering Reports, Volume 8, Issue 9, September 2026.
This study presents a hybrid AI framework for sustainable ecotourism management, combining TabNet and XGBoost to predict ecotourism risk levels. The system analyzes datasets including visitor numbers, resource consumption, visitor satisfaction, temperature, Air Quality Index (AQI), noise levels, timestamps, and location data.
Zhide Luo, Zihao Jiang
wiley   +1 more source

Beyond Traditional Screening: The Future of Heart Failure Detection With Biomarkers and AI

open access: yesiNew Medicine, Volume 2, Issue 3, September 2026.
Advancing HF Screening: Integrating Technology and Risk Factors Across Eras. This diagram provides a comprehensive review of the historical developments and projected trends of heart failure (HF) screening methodologies, with the prevalent risk factors for HF depicted at the base.
Xiaofeng Fang   +9 more
wiley   +1 more source

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