Results 111 to 120 of about 16,150 (212)

Tactile Perception of 3D‐Printed Typodont Materials in Dental Education: A Systematic Review

open access: yesEuropean Journal of Dental Education, EarlyView.
ABSTRACT Background Adoption of additive manufacture of printed typodonts within dentistry for education occurs despite inadequate reproduction of desirable tactile characteristics of human tooth tissues. Variable findings regarding material properties and educational outcomes of 3D‐printed typodonts are reported.
Alice M. G. Cheadle   +5 more
wiley   +1 more source

Mechanical stiffness orchestrates distinct regulation of MRTFs and YAP/TAZ transcriptional cofactors in hepatocytes

open access: yesThe FEBS Journal, EarlyView.
MRTFs and YAP/TAZ proteins, or mechanosensitive transcriptional cofactors (MRTcoF), regulate common genes associated with cellular contractility and immune cell infiltration. Their differential regulation in response to stiffness is linked to changes in hepatocyte's aspect ratio. MRTFB does not undergo nuclear translocation under these conditions. This
Brenda Selene Torres‐Ortiz   +13 more
wiley   +1 more source

GHT-SELEX demonstrates unexpectedly high intrinsic sequence specificity and complex DNA binding of many human transcription factors. [PDF]

open access: yesNat Methods
Jolma A   +12 more
europepmc   +1 more source

TOP1MT rs2293925 is an enhancer‐active regulatory SNP that shapes mitochondrial R‐loop dynamics

open access: yesThe FEBS Journal, EarlyView.
This study shows how a common genetic variant of mitochondrial topoisomerase 1 (TOP1MT rs2293925) can influence mitochondrial gene regulation, DNA topology, and formation of noncanonical nucleic acid structures such as R‐loops. By linking this enhancer‐active variant to mitochondrial nucleic acid stress in cellular contexts relevant to amyotrophic ...
Dóra Varga   +15 more
wiley   +1 more source

Natural variation in the GNH1 promoter enhances plant height and grain yield in rice

open access: yesJournal of Integrative Plant Biology, EarlyView.
Natural variation in the GRAIN NUMBER AND PLANT HEIGHT 1 (GNH1) promoter alleviates repression by the C2H2‐type transcription factor ZFP36, upregulating GNH1 expression and promoting auxin accumulation, thereby increasing rice plant height and grain yield. This elite allele serves as a valuable genetic resource for molecular breeding of high‐yield rice.
Hongwei Xing   +6 more
wiley   +1 more source

Expanding the Clinical Spectrum of DHX30‐Related Neurodevelopmental Disorder: A Case Report and a Scoping Review

open access: yesJournal of Intellectual Disability Research, EarlyView.
ABSTRACT Background Whole exome sequencing (WES) has improved diagnostic rates for neurodevelopmental disorders (NDDs) while introducing challenges in novel variant interpretation. DHX30‐related NDD (DHX30‐NDD) is a recently described condition with an evolving phenotypic spectrum.
Nattaporn Tassanakijpanich   +3 more
wiley   +1 more source

Health Literacy and Unmet Needs in Patients With Multiple Sclerosis: A Cross‐Sectional Study

open access: yesJournal of Clinical Nursing, EarlyView.
ABSTRACT Aims To identify a correlation between unmet needs and HL levels in people with Multiple Sclerosis (pwMS) and to evaluate how sociodemographic characteristics influence HL levels and unmet needs. Design A cross‐sectional study. Methods The study was conducted using a questionnaire including the HLS19‐Q12 to assess HL and the Long‐term Unmet ...
Francesco Pastore   +6 more
wiley   +1 more source

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