Results 31 to 40 of about 96,002 (257)

Seroprevalencia de la infección por Helicobacter pylori en pacientes con Gastritis Crónica, Úlcera Duodenal y Gástrica: Primer estudio de corte retrospectivo Seroprevalence of Helicobacter pylori infection in chronic gastritis patients, duodenal and gastric ulcer patients

Revista Cubana de Investigaciones Biomédicas, 2008
Objectivo. El objetivo de este estudio fue analizar la seroprevalencia de la población en tres centros hospitalarios, correspondientes a tres países; Venezuela, Cuba y República Dominicana. Métodos.
Beatriz Gutiérrez, María Eugenia Cavazza, Diana Ortiz, María Correnti, Teresita Vidal, Francis Mégraud, Manuel Guerram, Patricia Álvarez   +7 more
doaj  

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Multi‐Targeting Carnosic Acid Kills Drug‐Resistant Helicobacter pylori With Narrow‐Spectrum Activity

Advanced Science, EarlyView.
Carnosic acid selectively eradicates drug‐resistant Helicobacter pylori through a multi‐targeted mechanism involving urease inhibition, membrane disruption, and biofilm eradication. It exhibits no detectable resistance, potent in vivo efficacy, and minimal impact on gut microbiota, positioning it as a promising narrow‐spectrum lead compound against ...
Yuefan Bai, Hongming Huang, Xudong Hang, Shanwei Hu, Qian Tong, Jingchen Xu, Jia Jia, Hongkai Bi   +7 more
wiley   +1 more source

Gastric Stem Cells: Physiological and Pathological Perspectives

Frontiers in Cell and Developmental Biology, 2020
Gastric epithelium operates in a hazardous environment that curtails the lifespan of the constituent cells, imposing a requirement for continuous epithelial renewal.
Shiyu Xiao, Shiyu Xiao, Liya Zhou, Liya Zhou   +3 more
doaj   +1 more source

Lactobacillus acidophilus NCFM and Lactiplantibacillus plantarum Lp-115 inhibit Helicobacter pylori colonization and gastric inflammation in a murine model

Frontiers in Cellular and Infection Microbiology, 2023
PurposeTo determine the role of Lactobacillus strains and their combinations in inhibiting the colonization of H. pylori and gastric mucosa inflammation.MethodsHuman gastric adenocarcinoma AGS cells were incubated with H. pylori and six probiotic strains
Siqi Shen, Siqi Shen, FeiFei Ren, FeiFei Ren, Haiming Qin, Haiming Qin, Ihtisham Bukhari, Ihtisham Bukhari, Jing Yang, Dafang Gao, Arthur C. Ouwehand, Markus J. Lehtinen, Pengyuan Zheng, Pengyuan Zheng, Yang Mi, Yang Mi   +15 more
doaj   +1 more source

Targeting a Myeloid–Regulatory B Cell Network Reverses Immune Paralysis in Periprosthetic Joint Infections

Advanced Science, EarlyView.
Periprosthetic joint infection establishes a sophisticated immunosuppressive network between CXCR4+ PMN‐MDSCs and Bregs, inducing profound CD8+ T cell paralysis. Alendronate effectively disrupts this CXCR4+ PMN‐MDSC–Breg axis by targeting STAT3, thereby restoring local immune surveillance.
Jintao Wu, Shutao Zhang, Yumin Lin, Juyang Jiao, Zhiwei Fu, Qimin Hong, Ziyi Zhao, Xinhua Qu, Fei Su, Bing Yue   +9 more
wiley   +1 more source

Exploring the mechanism of curcumin in the treatment of colon cancer based on network pharmacology and molecular docking

Frontiers in Pharmacology, 2023
Objective: Curcumin is a plant polyphenol extracted from the Chinese herb turmeric. It was found that curcumin has good anti-cancer properties in a variety of cancers, but the exact mechanism is not clear.
Qingmin He, Qingmin He, Chuan Liu, Xiaohan Wang, Xiaohan Wang, Kang Rong, Kang Rong, Mingyang Zhu, Mingyang Zhu, Liying Duan, Liying Duan, Pengyuan Zheng, Pengyuan Zheng, Pengyuan Zheng, Yang Mi, Yang Mi, Yang Mi   +16 more
doaj   +1 more source

Disrupting Helicobacter pylori Iron Homeostasis With Bismuth Nanodrug‐Mediated Nutritional Trap for Targeted Gastric Infection Therapy

Advanced Science, EarlyView.
A “nutritional trap” strategy centered on disrupting bacterial iron homeostasis is proposed. The synthesized Bi‐TP@FU (TBF) can target Helicobacter pylori, interfere with the bacterial iron uptake and utilization processes to disrupt its iron homeostasis, induce bacterial death, and meanwhile preserve the balance of the intestinal flora.
Tianye Fang, Jinzhe Tong, Feng Feng, Cong Liu, Chang Shu, Jiaying Zhu, Shibo Zhang, Shuyue Deng, Wanchao Zuo, Yuhan Song, Jun Yang, Yanmin Ju, Yingying Xing, Jianjun Dai   +13 more
wiley   +1 more source

The mechanism of vitamin D3 in preventing colorectal cancer through network pharmacology

Frontiers in Pharmacology, 2023
Objective: Colorectal cancer (CRC) is a common cancer that cannot be detected at an early stage and is a major challenge in oncology research. Studies have shown that vitamin D3 has some anti-cancer and preventive effects on colorectal cancer, but the ...
Kang Rong, Kang Rong, Qingmin He, Qingmin He, Shu Chen, Yong Yu, Yong Yu, Lu Mei, Lu Mei, Yang Mi, Yang Mi, Liufan Mu, Liufan Mu, Mingyang Zhu, Mingyang Zhu, Mengjiao Nan, Mengjiao Nan, Xiaoyang Zhang, Xiaoyang Zhang, Zhaoyang Wan, Zhaoyang Wan, Huang Huang, Huang Huang, Pengyuan Zheng, Pengyuan Zheng   +24 more
doaj   +1 more source

Deciphering Anti‐Cancer Drug Efficacy Through Nanomechanical Vibrations in Living Gastric Cancer Organoids

Advanced Science, EarlyView.
This study developed an efficacy assessment platform that integrates patient‐derived gastric cancer organoids, atomic force microscopy (AFM)‐based nanomechanical vibration detection, deep learning analysis, and organoid mechanical modeling. It detects picomolar drug effects within 0.1 s signal, achieves 97% classification accuracy, and offers non ...
Ting Zhang, Qiubo Chen, Shihai Lan, Liang Zhu, Shuaiyu Liu, Yan Xia, Yalu Zhang, Hanhui Yao, Yongman Liu, Shangquan Wu, Qingchuan Zhang   +10 more
wiley   +1 more source